RFX3 is essential for the generation of functional human pancreatic islets from stem cells by Bushra Memon (4792767)

“…The loss of <i>RFX3</i> disrupted pancreatic endocrine gene regulation, reduced the number of hormone-secreting islet cells and impaired beta cell function and insulin secretion. Despite a significant reduction in the expression levels of pancreatic islet hormones, the pan-endocrine marker chromogranin A remained unchanged at both EP and islet stages, likely due to an increase in the abundance of enterochromaffin cells (ECs). …”

Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank by Mohammed Al-Hamdani (16962702)

“…However, BMD measures significantly contributed to predicting stiffness after controlling for sociodemographic variables (R² = 0.065, ΔF(7, 1724) = 3.34, p= 0.002), with a higher total body BMD associated with increased stiffness and a higher trunk BMD associated with decreased stiffness. …”

Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breas... by Basala, Sobhiya

“…Later we detected uPAR levels in breast cancer cell lines. MDA-MB-231 had the most significant uPAR expression, MCF-7 had a moderate level of expression, and UACC-2087 had negligible expression. …”
Get full text
Get full text
Get full text

The protective effects of conditioned media from human mesenchymal stem cells against Methylglyoxal-mediated injury of cultured endothelial cells by Maram Hasan (6672440)

“…We noted that only the mRNA expression of Nrf2 was increased in cells treated with MSCs-CM (50%). At the protein expression level, our results demonstrated that MSCs-CM (50%) enhanced the expression of the detoxifying NQO1in MGO-injured cells.…”

Inappropriate Medication Use in Elderly Lebanese Outpatients by Saab, Yolande B.

“…With increasing availability of newer and more appropriate medications, use of potentially inappropriate drugs may decrease. Pharmacists have a major role to play in counselling patients about the importance of appropriate drug use.…”
Get full text
Get full text
Get full text
Get full text

Ratings of Perceived Exertion Misclassify Intensities for Sedentary Older Adults During Graded Cycling Test: Effect of Supramaximal High-Intensity Interval Training by Georges Jabbour (754884)

“…For both groups, RPE decreases with SCE at 10 min following graded test correlated significantly to V˙O₂ (r = 0.61, p < 0.01). …”

The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function by MUBARAK, ALIA MARJAN

“…While a significant sector of research is devoted to risk management in Europe and the United States, the unique culture, location and economy of the United Arab Emirates and Dubai, in particular, have to be incorporated into the understanding of local risk management in order to reach the best outcomes. …”
Get full text

Exploring the association between the consumption of beverages, fast foods, sweets, fats, and oils and the risk of gastric and pancreatic cancers: Findings from case–control study... by Reem Almahri (22224316)

“…Multinomial logistic regression was utilized to calculate odds ratios (ORs) along with their corresponding 95% confidence intervals (CIs). Significance was determined at a level of <i>P</i>< 0.05. …”

Waterpipe Tobacco Smoke Nicotine Mediates Resilience to Chronic Stress by Activating BDNF Signaling by Khalifeh, Mohamad Rabieh

“…Even though initially, WTS decreased anxiety-like behaviors it was found that prolonged exposure after the completion of CSDS significantly induced anxiety-like behaviors. …”
Get full text
Get full text
Get full text

Breast cancer cells and bone marrow mesenchymal stromal cells by Faour, Wissam H.

“…While co-culture assays with SaOS-2 increased the expression of osteoblastic markers in MCF-7 cells, SaOS-2 cell conditioned medium increased the expression of RANKL, PTHrP, VEGF and NOGGIN in MCF-7 cells. …”
Get full text
Get full text
Get full text

Targeting solid tumor cells with novel photosensitive ruthenium-based metal-organic compounds. (c2016) by Farhat, Stephanie Roy

“…Cancer incidence has been increasing worldwide in the last few decades. Solid tumors are hard to treat, primarily due to drug resistance as well as to the struggle in delivering the drugs specifically to the tumor. …”
Get full text
Get full text
Get full text

Road deaths and injuries in India: Action required on the five pillars of road safety by Gopalakrishna Gururaj (19807233)

“…The economic losses from road crashes are estimated to be 3% of GDP and are increasing from year to year (2). Amidst significant regional variations, many Indian states have road deaths much above the national average. …”

Longitudinal Study of Hypertensive Subjects With Type 2 Diabetes Mellitus by Bahous, Sola Aoun

“…Using cross-sectional regression models, a significant association was observed between higher education levels, lower levels of anxiety and depression, and reduced overall mortality in diabetic hypertensive subjects, while impaired renal function, a history of stroke and myocardial infarction, and increased alcohol and tobacco consumption were significantly associated with increased mortality. …”
Get full text
Get full text
Get full text
Get full text

Feeder protection challenges with high penetration of inverter based distributed generation by Margossian, Haraj

“…The increasing proportion of inverter based distributed generation (DG) in the power system may limit the short circuit power available at distribution substations and consequently cause significant troubles for the protection of distribution feeders where DG are connected. …”
Get full text
Get full text
Get full text
Get full text

A Brief Review on the Development Progress of High-Efficiency Klystrons by Soumaya Mandal (22467694)

“…The development of mathematical and computer models of beam-wave interactions in klystrons plays a pivotal role in significantly increasing the efficiency of these devices. …”

Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer by Shebaby, Wassim N.

“…Results All fractions exhibited significant cytotoxicity, with HaCaT cells being 2.4–3 times less sensitive than HaCaT-ras A5 (benign tumorigenic), and HaCaT-ras II4 (malignant) cells. …”
Get full text
Get full text
Get full text
Get full text

Effect of sintering temperature of NBT–6BT lead-free ceramics on the structural, ferroelectric and piezoelectric properties by Slimani, Ahmed

“…The XRD results show that the 850 °C is the best calcination temperature, where the NBT-6BT ceramic had the largest crystallite size with a dense sample, 96% of the theoretical value. However, the density decreased significantly with increasing the calcination temperature above 850 °C due to the secondary phase formation. …”
Get full text

Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema by Diab, Khalil J.

“…The effects of increased endogenous ceramides could be offset by sphingosine 1-phosphate (S1P), a prosurvival by-product of ceramide metabolism. …”
Get full text
Get full text
Get full text
Get full text

Phosphate-solubilizing bacteria-mediated rock phosphate utilization with poultry manure enhances soil nutrient dynamics and maize growth in semi-arid soil by Kashif Khan (2978691)

“…The integration of RP and PM, particularly with PSB inoculation, significantly (p < 0.05) improved soil and plant nitrogen (N), phosphorus (P), and potassium (K) levels. …”

Predicting stability of classes in an object-oriented system by Azar, D.

“…However, in almost all cases, these models were not efficient when used to predict the quality characteristics (stability or other) of new unseen software as their prediction accuracy decreases significantly. In this paper, we present a heuristic approach that relies on the adaptation and recombination of already built predictive models to new unseen software.The predictive models are all rule-based models and the approach is tested on the stability of classes in an object-oriented software system. …”
Get full text
Get full text
Get full text