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241
Hydroxyurea Use in Lebanese Patients With [beta]-Thalassemia Intermedia
Published 2006“…Hematologic toxicity was defined as a decrease in the absolute neutrophil count to below 1.5 × 103/mm3 or a decrease in the platelet count to below 100 × 103. …”
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242
IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells
Published 2002“…They also caused a slight but significant increase in the G2/M phase. …”
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243
Occupational Violence at Lebanese Emergency Departments
Published 2011“…Exposure to verbal abuse was associated with serious outcomes including significantly higher levels of occupational burnout and an increased likelihood to quit current job. …”
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244
BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells
Published 2020“…</p><h3>Results</h3><p dir="ltr">Treatment of human breast cancer cells with increasing concentrations of VCX caused a significant decrease in cells growth and proliferation. …”
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245
Chemical characterization and cytotoxic activity evaluation of Lebanese propolis
Published 2017“…Toxicity started early after 24 h of incubation and remained till 72 h. Interestingly, the decrease in cell viability was accompanied by a significant increase in p53 protein expression levels and PARP cleavage. …”
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246
Myeloid Cells in Circulation and Tumor Microenvironment of Colorectal Cancer Patients with Early and Advanced Disease Stages
Published 2020“…Lastly, we found that levels of GMCs decreased, while IMCs increased in the TME with tumor budding. …”
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247
Acute exposure to cigarette smoking followed by myocardial infarction aggravates renal damage in an In vivo mouse model
Published 2017“…Finally, reactive oxygen species (ROS) production was significantly accentuated in S+MI group concomitant with a significant increase in NOX-4 protein levels. …”
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248
Local arterial vasoconstriction induced by octreotide in patients with cirrhosis
Published 2000“…FBF in the control arm was unchanged despite a significant decrease in systemic glucagon levels. …”
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Multivariate epidemiologic analysis of type 2 diabetes mellitus risks in the Lebanese population
Published 2014“…People with T2DM showed a significant decrease in HDL-C levels. A strong correlation of overall hyperlipidemia with the diabetes affection status was shown (p < 0.0001). …”
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251
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”
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252
Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats
Published 2020“…Equally, it showed a rise of the apoptotic markers (a decrease in the expression of the Bcl-2 and an increase of the P53). …”
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253
Impact of Using Recycled Materials in the Construction Industry of the United Arab Emirates
Published 2015“…The main barrier to the achievement of sustainability relates to the increasing levels of wastes generated in the industry. …”
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254
Analyzing the Influence of Climate and Anthropogenic Development on Vegetation Cover in the Coastal Ecosystems of GCC
Published 2025“…Our results revealed significant changes in land cover, as seen by an increase in artificial built-up areas by 15.5% in two decades and a corresponding decrease in bareland and dense vegetation. …”
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255
Long-term antibiotic resistance surveillance of gram-negative pathogens suggests that temporal trends can be used as a resistance warning system
Published 2002“…The significant trend of increased resistance to antibiotics over time constitutes an important warning system.…”
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256
Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling
Published 2020“…Stretching the RPV also significantly increased ROS generation after 1 hour, whereas APN significantly decreased mechanical stretch-induced ROS production. …”
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257
Social Media Use and Body Checking Among Lebanese Adults
Published 2022“…Background: The recent increase in social media use has been associated with body checking and body image dissatisfaction. …”
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258
Fourier-Transform Infrared Imaging Spectroscopy and Laser Ablation -ICPMS New Vistas for Biochemical Analyses of Ischemic Stroke in Rat Brain
Published 2018“…</p><p dir="ltr"><br></p><h3>Results</h3><p dir="ltr">The FTIR results revealed that in the lesioned gray matter the relative distribution of lipid, lipid acyl and protein contents decreased significantly. Also at this locus, there was a significant increase in aggregated protein as detected by high-levels Aβ1-42. …”
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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Published 2019“…We also found increased levels of LAMP-1 and LAMP-2A both <i>in vitro</i> and <i>in vivo</i>, along with decreased levels of α-synuclein. …”
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Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles
Published 2011“…In females, although no correlation between LINE-1 or Alu methylation and hormone levels was observed, a significant stable individual specific level of methylation was noted. …”
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