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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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23
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
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24
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25
National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050
منشور في 2024"…BackgroundOver the past several decades, the overweight and obesity epidemic in the USA has resulted in a significant health and economic burden. Understanding current trends and future trajectories at both national and state levels is crucial for assessing the success of existing interventions and informing future health policy changes. …"
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article -
26
National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050
منشور في 2024"…BackgroundOver the past several decades, the overweight and obesity epidemic in the USA has resulted in a significant health and economic burden. Understanding current trends and future trajectories at both national and state levels is crucial for assessing the success of existing interventions and informing future health policy changes. …"
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27
Growth hormone treatment modulates active ghrelin levels in rats
منشور في 2014"…Genotropin treatment caused a dose dependent decrease in active ghrelin concentration in stomach, kidney and pancreas with a concomitant increase in plasma, and reaching significance at 20 and 100 µg/rat/day doses. …"
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28
Prediction of the Backwater Level Due to Bridge Constriction in Waterways
منشور في 2019احصل على النص الكامل
doctoralThesis -
29
Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …"
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30
Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data
منشور في 2017"…After accounting for the role of coal as a baseload power source, an increase in the share of renewable energy is estimated to mitigate N2O emissions at the U.S. state level only if states individually decrease their share of coal use to levels below 41.47%. …"
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31
Revisiting the economic theory of crime A state-level analysis in India
منشور في 2023"…An increase in the likelihood of arrest and apprehension should deter criminals as it increases the expected costs of committing crimes. …"
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Resource allocation and reallocation techniques in high-level synthesis with testability constraint
منشور في 1994"…The increase in density that the advent of Very Large Scale Integration (VLSI) has allowed, made the move to higher levels of design abstraction imperative. …"
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masterThesis -
34
Higher serum leptin level in women than in nen with type 1 diabetes
منشور في 2002"…In humans, serum leptin concentrations are increased in relation to increased body fat content. …"
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35
National-level resilience: Innovative framework for Energy-Water-Food nexus evaluation
منشور في 2024"…<p dir="ltr">The escalating demand for energy, water, and food (EWF) resources, alongside external stressors such as climate change, is placing significant strain on national systems. Therefore, this study introduces a novel framework for assessing the resilience of interconnected EWF systems at a national level. …"
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36
The effect of vancomycin doses greater than 2 grams on serum creatinine and vancomycin trough levels
منشور في 2014"…The use of doses greater than 2 grams of IV vancomycin did not show a statistically significance increase in serum creatinine. The two subjects who did have a significant increase in serum creatinine were receiving concomitant nephrotoxins. …"
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article -
37
Systematic review on ammonia as a sustainable fuel for combustion
منشور في 2024"…Using bibliometric techniques, data from research publications spanning 2000 to 2024 were gathered from the Web of Science database, revealing that publication numbers remained low until 2015 but increased significantly from 2016 onward. This research systematically analyzes numerical and experimental studies on combustion characteristics and technologies across the last forty years. …"
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38
Design analysis and experimental validation of a multi‐level inverter for vehicle to home application
منشور في 2023"…A reduced number of switches with a single DC source (EV battery) is used to generate the 11‐level of output voltage and current waveform. The proposed topology is quite simple in structure and ensures the increase of two levels with each additional switch. …"
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39
Mechanical Efficiency at Different Exercise Intensities Among Adolescent Boys With Different Body Fat Levels
منشور في 2019"…These findings suggest that excess in body weight exerts a negative effect on ME at a low intensity by increasing energy consumption for obese and overweight adolescent boys, while at higher intensities (75%HRmax and VO<sub>2peak</sub>) the lower ME could be better explained by the lower power output and catecholamine responses that were attenuated among obese and overweight adolescent boys.…"
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40
Exploring Ultra-Processed Foods: Impact on Satiety, Eating Patterns, Blood Glucose Levels and Food Addiction
منشور في 2025"…However, no significant associations were found between UPF intake and emotional eating, overall satiety ratings, psychological distress (PHQ-4), or fasting BG levels (p = 0.171). …"
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masterThesis