Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

"…We characterized variants in <i>CCL5</i> and that of six other CCL5 signaling genes (<i>CCND1, ZMIZ1, CASP8, NOTCH2, MAP3K21, and HS6ST3</i>) among 1,082 unrelated Tunisian subjects (544 BC patients, including 196 TNBC, and 538 healthy controls), assessed the association of the variants with BC-specific overall survival (OVS) and progression-free survival (PFS), and correlated CCL5 mRNA and serum levels with <i>CCL5</i> genotypes. We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …"

The differential impact of IFRS adoption on aspects of seasoned equity offerings in the UK and France حسب Harakeh, Mostafa

"…As a result of the lower levels of earnings management and information asymmetry, we predict and find that the market reaction to issuing SEOs improves significantly for high-divergence firms following IFRS. …"
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Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59 حسب Ramada R. Khaswaneh (22224544)

"…</p><h3>Conclusion</h3><p dir="ltr">The loss of Factor H and CD59 in hypoxic MSCs can initiate their lysis and apoptosis mediated by activating MAC complex. Preserving the level of Factor H and CD59 in MSCs has significant clinical implication to increase their retention rate in hypoxic conditions and prolong their survival.…"

Chemical characterization and cytotoxic activity evaluation of Lebanese propolis حسب Faour, Wissam H.

"…Toxicity started early after 24 h of incubation and remained till 72 h. Interestingly, the decrease in cell viability was accompanied by a significant increase in p53 protein expression levels and PARP cleavage. …"
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Acute exposure to cigarette smoking followed by myocardial infarction aggravates renal damage in an In vivo mouse model حسب Kobeissy, Firas

"…Finally, reactive oxygen species (ROS) production was significantly accentuated in S+MI group concomitant with a significant increase in NOX-4 protein levels. …"
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Fourier-Transform Infrared Imaging Spectroscopy and Laser Ablation -ICPMS New Vistas for Biochemical Analyses of Ischemic Stroke in Rat Brain حسب Mohamed H. M. Ali (5768066)

"…</p><p dir="ltr"><br></p><h3>Results</h3><p dir="ltr">The FTIR results revealed that in the lesioned gray matter the relative distribution of lipid, lipid acyl and protein contents decreased significantly. Also at this locus, there was a significant increase in aggregated protein as detected by high-levels Aβ1-42. …"

Meal pattern of male rats maintained on histidine-, leucine-, or tyrosine-supplemented diet. حسب Bassil, Maya S.

"…Both histidine and tyrosine supplementation elevated fasting plasma insulin levels and suppressed fasting glucose significantly. …"
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Impact of Using Recycled Materials in the Construction Industry of the United Arab Emirates حسب Al Zarouni, Tariq

"…The main barrier to the achievement of sustainability relates to the increasing levels of wastes generated in the industry. …"
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Mammary adipose dysfunction in the dual epidemic of obesity and breast cancer حسب Elvina Jeyakumar (22997311)

"…<p dir="ltr">Breast cancer (BC) is one of the leading causes of death among women, with obesity being a significant factor. Mammary adipose tissue (MAT) dysfunction in obesity creates a tumor-supportive environment, leading to increased risk. …"

Inflammatory Markers and COVID-19 Disease Progression حسب Santosh Kumar Sidhwani (16488557)

"…Almost all patients exhibited increased levels of various inflammatory markers, with procalcitonin (97.2%) being the most common. …"

Adaptive Effects of Seeing Green Environment on Psychophysiological Parameters When Walking or Running حسب Walid Briki (688845)

"…Study 2 showed that running in a green environment was associated with an increased level of perceived exertion at similar speeds (compared to other color conditions), while exposure to red induced a significant decrease in the level of tension. …"

Anti-xa guided enoxaparin thromboprophylaxis is associated with less thromboembolism than fixed dose dalteparin in trauma patients admitted to intensive care حسب Ahmad Kloub (16855149)

"…</p><h3>Conclusion</h3><p dir="ltr">Among adult patients in the trauma ICU, compared to a fixed dose dalteparin, enoxaparin prophylaxis with dose calibration according to peak anti-Xa levels was associated with lower VTE rates without increasing the risk of bleeding. …"

STARD 13 in prostate cancer. (c2018) حسب Saab, Sahar S.

"…Knocking down StarD13 by siRNA led to an increase in cell proliferation and adhesion yet a decrease in cell motility and cell speed in prostate cancer. …"
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Willingness to Pay for Clean Air: Evidence from the UK حسب Maarraoui, Giorgio

"…The willingness to pay for clean air is also significant and increases with level of education. These measurements derived can be used as benchmarks for pollution abatement subsidies or pollution taxes and can help in projecting a more comprehensive assessment of costs and benefits.…"
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Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway حسب Olfa Khalifa (10914452)

"…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …"

Assessing the Relationship Between Motivation and Foreign Language Anxiety: The Role of Variance حسب Boktor, Mary

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Minimizing Traffic Congestion through V2V Communication حسب Alqawasmeh, Suhieb

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Communication Network for Ultrasonic Acoustic Water Leakage Detectors حسب Awwad, Ameen

"…Acoustic detectors were found the most suitable technology for the atmosphere in UAE, where the levels of humidity and, consequently, soil moisture are high, because both of GPRs and IR cameras operational capability to detect leaks tend to decrease sharply as soil moisture increases. …"
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Breast cancer cells and bone marrow mesenchymal stromal cells حسب Faour, Wissam H.

"…While co-culture assays with SaOS-2 increased the expression of osteoblastic markers in MCF-7 cells, SaOS-2 cell conditioned medium increased the expression of RANKL, PTHrP, VEGF and NOGGIN in MCF-7 cells. …"
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Anticancer and antioxidant effects of tragopogon porrifolius extract. (c2011) حسب Tenkerian, Clara A.

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