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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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20301
Data Sheet 1_Landscape analysis of m6A modification regulators reveals LRPPRC as a key modulator in tubule cells for DKD: a multi-omics study.docx
Published 2025“…Background<p>Diabetic Kidney Disease (DKD) is a serious complication of diabetes, imposing a substantial medical burden. The significance of N6-methyladenosine (m6A) modification in the pathogenesis of DKD has become increasingly prominent.…”
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20302
Prognostic value of miR-378c in hepatocellular carcinoma and its regulatory effect on tumor progression
Published 2025“…</p> <p>Serum miR-378c expression is decreased in HCC patients and strongly connected with poor prognosis. …”
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20303
Supplementary file 2_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg
Published 2025“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”
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20304
Assessment of the relationship between adiposity, Sirtuin 1, and miR-30a-5p in a mixed-ancestry population in Bellville South, Cape Town.
Published 2025“…SIRT1 protein concentration decreased with obesity, consistent with miR-30a-5p-mediated repression, while <i>SIRT1</i> gene expression was increased in obese and high WC groups, suggesting post-transcriptional regulation of <i>SIRT1</i> by miR-30a-5p.…”
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20305
<b>Astragalus polysaccharide and </b><b><i>Clostridium butyricum</i></b><b> synergistically inhibit bone loss in mice with humanized intestinal flora</b>
Published 2025“…We used a humanized intestinal flora mouse model and showed that APS-CB significantly inhibited bone loss caused by simulated weightlessness. …”
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20306
Image_1_ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1.jpg
Published 2025“…Results from immunohistochemistry show that the expression of ATG5 and ATG7 is significantly reduced in melanoma tissues compared to benign nevi. …”
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20307
Image 4_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.jpeg
Published 2025“…Purpose<p>Diabetic cardiomyopathy (DCM), which is diabetes mellitus-induced cardiomyopathy, significantly elevates the risk of heart failure and sudden cardiac death. …”
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20308
Candidate genes by Genome-wide CRISPR Screen.
Published 2024“…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”
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20309
Image 5_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.tif
Published 2025“…Purpose<p>Diabetic cardiomyopathy (DCM), which is diabetes mellitus-induced cardiomyopathy, significantly elevates the risk of heart failure and sudden cardiac death. …”
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20310
RNA quality photo
Published 2025“…Moreover, although the expression of the GRP78 gene increased in the sinus tissue of diabetic patients with mucormycosis, it significantly decreased in the same patients after treatment. …”
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20311
Supplementary Material for: Global, regional, and national burden of motor neuron disease: a systematic analysis of prevalence, incidence, deaths, and DALYs with projections to 203...
Published 2025“…Results: From 1990 to 2021, the global number of MND cases, deaths, and DALYs increased significantly, while the age - standardized prevalence and incidence rates decreased. …”
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20312
Image 6_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.jpeg
Published 2025“…Purpose<p>Diabetic cardiomyopathy (DCM), which is diabetes mellitus-induced cardiomyopathy, significantly elevates the risk of heart failure and sudden cardiac death. …”
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20313
Table 2_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf
Published 2025“…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …”
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20314
Point Application Therapy Targeting Feishu, Pishu and Shenshu Attenuates Asthma by Suppressing Autophagy and the AMPK-mTOR Signalling Pathway
Published 2025“…The treatment additionally decreased expression levels of mTOR, LC3, NF-κB and TGF-β1 while increasing AMPK content. …”
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20315
Kalman process.
Published 2025“…Following model updates with measured data, the accumulated prediction error rapidly decreases. The proposed prediction method for shape errors during pushing exhibits high accuracy and versatility in similar projects, significantly reducing time spent on manual error handling and minimizing computational inaccuracies.…”
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20316
Image 3_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg
Published 2025“…Administration of exogenous H<sub>2</sub>S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …”
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20317
Data Sheet 1_Early coronary angiography in patients with myocardial infarction without ST elevation after out-of-hospital cardiac arrest: a systematic review and meta-analysis.pdf
Published 2024“…Observational study subgroup showed decreased short-term mortality, long-term mortality, and CPC 1–2 at discharge, unlike RCT subgroup. …”
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20318
Supplementary file 1_Bioactive fraction isolated from Curcuma angustifolia rhizome exerts anti-diabetic effects in vitro, in silico and in vivo by regulating AMPK/PKA signaling pat...
Published 2025“…After 28 days of intervention, the lower and higher doses of the bioactive fraction (100 and 200 mg/kg BW) substantially decreased fasting blood glucose levels and ameliorated hyperglycemia, glucose intolerance, insulin resistance, and hyperlipidemia. …”
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20319
Data Sheet 1_Effect of cultivation feed diet using local food processing by-products on the growth and flavor factor in the Malabar grouper Epinephelus malabaricus.docx
Published 2025“…FW-D-fed fish also exhibited significantly increased muscle levels of unsaturated fatty acids, particularly docosahexaenoic acid (DHA), a nutrient beneficial for human health. …”
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20320
Data Sheet 1_Total flavonoids isolated from Eucommia ulmoides can alleviate bone loss and regulate intestinal microbiota in ovariectomized rats.docx
Published 2025“…</p>Results<p>Oral administration of TFEL for 13 weeks increased the serum level of bone formation marker PINP and decreased the level of bone resorption marker NTX-I. …”