Combating Chemoresistance in Breast Cancer: Exploring Tumor Microenvironment, Combination Therapies, and Drug Repurposing Strategies by Shazia Sofi (17764488)

“…Chemoresistance in cancer can arise from a variety of molecular mechanisms, including active drug expulsion (drug efflux), decreased drug uptake, enhanced DNA repair mechanisms, the ability of cancer cells to evade programmed cell death (apoptosis), the diversity in the population of cancer cells within a tumor (tumor heterogeneity), and significant alterations in the tumor microenvironment (TME), where interactions between cancer cells, cancer-associated fibroblasts, immune cells, and the extracellular matrix contribute to a supportive environment that allows tumors to survive treatment and escape therapy. …”

Table 1_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.docx by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.…”

Image 11_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.…”

Table 2_Elucidating the impact of organic amendments on soil bacterial communities and strawberry yield in North Carolina.xlsx by Tika B. Adhikari (9310247)

“…Organic amendments can alter microbial communities and increase crop productivity. …”

Data Sheet 1_Causal relationship between gut microbiota and diabetic neuropathy: a Mendelian randomization and 16S rRNA sequencing analysis.zip by Yingqing Hu (22307608)

“…Sequencing analyses further revealed significant alterations in gut microbiota composition in both DPN mice and DPN patients compared to control group.…”

Presentation 1_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.pptx by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.…”

DataSheet1_Interannual temperature rise leads to more uniform phenological matching between invasive Stellera chamaejasme and pollinators across elevations.pdf by Chenxin Miao (19834812)

“…<p>Exploring how environmental changes induce alterations in the phenology matching between plants and pollinators is significant for predicting species’ reproductive output and population dynamics. …”

Presentation1_Exchange flow in a highly stratified fjord in drought conditions.pdf by Elias Pinilla (20400329)

“…Logistic regression models showed significant links between stratification levels and harmful algal blooms (HABs) of Pseudchatonella spp. and Alexandrium catenella. …”

Table 2_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.docx by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.…”

Image 9_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.…”

Image 3_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.…”

Supplementary file 1_Elucidating the impact of organic amendments on soil bacterial communities and strawberry yield in North Carolina.pdf by Tika B. Adhikari (9310247)

“…Organic amendments can alter microbial communities and increase crop productivity. …”

Data Sheet 1_The effects of sleep deprivation on cognitive flexibility: a scoping review of outcomes and biological mechanisms.docx by Xuefeng Sun (408801)

“…The primary biological mechanisms involve decreased cerebral oxygen supply, impaired cerebrovascular reactivity, and alterations in gene expression and hormone levels. …”

Image 10_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.…”

Image 8_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif by Helena Hernández-Cuervo (9956465)

“…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.…”

Table 1_Elucidating the impact of organic amendments on soil bacterial communities and strawberry yield in North Carolina.xlsx by Tika B. Adhikari (9310247)

“…Organic amendments can alter microbial communities and increase crop productivity. …”

Image 1_Snowmelt seepage fluxes of dissolved organic matter in forest and grassland – a molecular-level case study from the Hainich Critical Zone Exploratory, Germany.pdf by Chen Huang (202847)

“…This study, conducted at the Hainich Critical Zone Exploratory in Germany, seeks to address a significant gap in understanding the molecular impacts of snowmelt-induced DOM flows and their ability to alter soil ecosystems rapidly. …”

Table 1_Polygonatum cyrtonema Hua polysaccharides alleviate muscle atrophy and fat lipolysis by regulating the gut microenvironment in chemotherapy-induced cachexia.docx by Rongrong Zhou (3341903)

“…</p><p>Results: This study demonstrated that PCPs significantly mitigated body weight loss, restored muscle fiber atrophy and mitochondrial disorder, alleviated adipose tissue wasting, strengthened the intestinal barrier integrity, and decreased the intestinal inflammation in chemotherapy-induced cachexia. …”

Data Sheet 6_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf by Sadia Hamera (22524803)

“…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”

Supplementary file 1_Role and mechanism of IGFBP5 in the real-ambient particulate matter exposure-induced chronic lung injury.docx by Ningning Chen (509273)

“…Transcriptomics was employed to analyze gene expression alterations.</p>Results<p>IGFBP5 was significantly downregulated after PM exposure. …”