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861
Intratumoral FoxP3<sup>+</sup>Helios<sup>+</sup> Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer
Published 2017“…Levels of CD4<sup>+</sup>FoxP3<sup>+</sup>Helios<sup>+</sup> Tregs were significantly increased in the TME. Furthermore, we observed increased levels of PD-1/CTLA-4 and PD-1/CD39 co-expressing cells within FoxP3<sup>+</sup>Helios<sup>+</sup> and FoxP3<sup>+</sup>Helios<sup>−</sup> Treg subsets, indicative of their potent immunosuppressive potential. …”
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862
Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese
Published 2018“…Indeed, HSP60 expression levels in SAT were significantly increased by exercise in the diabetes group, whereas they were decreased in the non-diabetes group. …”
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863
PermGuard: A Scalable Framework for Android Malware Detection Using Permission-to-Exploitation Mapping
Published 2024“…The increasing reliance on mobile devices significantly raises the risk of malware attacks, especially for non-technical users who often grant permissions without thorough evaluation, leading to potentially devastating effects. …”
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864
The safety of outpatient total shoulder arthroplasty: a systematic review and meta-analysis
Published 2022“…<h2>Purpose</h2> <p>To meet the increasing demands of total shoulder arthroplasty (TSA) while reducing its financial burden, there has been a shift toward outpatient surgery. …”
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865
Using Data Mining and Text Mining Techniques in Predicting the Price of Real Estate Properties in Dubai
Published 2014“…In this thesis, the effectiveness of using linear regression modeling as a data mining technique in predicting the price of a real estate property based on online real estate classifieds is examined. …”
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866
A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce...
Published 2008“…Although WP1066 did not induce immunologic memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (transforming growth factor-β, RANTES, MCP-1, vascular endothelial growth factor), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …”
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867
Numerical investigation of design strategies to achieve perpetual pavements
Published 2012“…This study investigates the effectiveness of several design strategies involved in long-life, perpetual pavement design. …”
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868
Modelling, analysis, and implementation of a switched‐inductor based DC/DC converter with reduced switch current stress
Published 2021“…The detailed modes of operation in both continuous conduction mode (CCM) and discontinuous conduction mode (DCM) and steady-state analysis, the non-idealities’ effect on voltage gain, design approach, and a comparative study with other DC-DC converters for some significant performance characteristics are provided. …”
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869
The Impact of Capital Formation on Economic Diversification in GCC Countries—Empirical Analysis Based on the PVAR Model
Published 2023“…The main objective of this study was to determine whether GCC countries’ capital formation has appreciable impulse effects on response–economic diversification in the short or long term. …”
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870
The Impact of Nutritional Supplementation During Pregnancy on the Incidence of Gestational Diabetes and Glycaemia Control
Published 2022“…Gestational Diabetes Mellitus (GDM) is the most common medical complication in pregnancy and is associated with significant maternal and fetal morbidity. Several studies have examined the effect of physical activity, healthy eating, and various food supplements on the risk of developing gestational diabetes (GDM) and related outcomes. …”
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871
Hydrogen bonding: a mechanism for tuning electronic and optical properties of hybrid organic–inorganic frameworks
Published 2016“…Here we demonstrate that significant progress in this area may be achieved by introducing structural elements that form hydrogen bonds with the environment. …”
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872
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873
Enhancing Thermal Comfort in Urban Communities with Urban Configurations and Green Coverage: A Case Study of Dubai Sustainable City
Published 2017“…The findings indicate that the layout orientation of the master plan has a significant effect on air temperature, wind speed and wind distribution within the site. …”
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874
Examining the Role of Innovative Leadership in Enhancing Student Achievement: Strategies and Outcomes
Published 2024“…The study enhances the current research by offering insights into effective leadership tactics amid changing educational requirements. …”
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875
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876
An empirical study of the impact of knowledge management strategies on waste and rework reduction in construction projects during post-contract award stage in UAE
Published 2018“…The requirement to reduce rework can have significant sustainable benefits to the construction sector in UAE.…”
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877
Mobile Energy Storage Systems for Benefit Maximization in Resilient Smart Grids
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878
Silver-based dressings for the prevention of surgical site infections: evidence from randomized trials
Published 2025“…<h3>Background</h3><p dir="ltr"><u>Surgical site infections</u> (SSIs) are a major cause of <u>postoperative complications</u>, increasing morbidity and healthcare costs. Silver-based dressings are commonly used due to their <u>antimicrobial properties</u>, but their effectiveness in reducing SSIs remains unclear. …”
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879
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880
20-HETE and EETs in Diabetic Nephropathy: A Novel Mechanistic Pathway
Published 2013“…In conclusion, we show that hyperglycemia in diabetes has a significant effect on the expression of Arachidonic Acid (AA)-metabolizing CYPs, manifested by increased AA metabolism, and might thus alter kidney function through alteration of type and amount of AA metabolites.…”