Methicillin-resistant Staphylococcus aureus ST80-IV clone in children from Jordan حسب Hashwa, Fuad

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In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model حسب Maram, Hasan

"…Our findings demonstrated that the NO-RPs improved the survival rate in the heart failure zebrafish model and reversed heart failure by enhancing blood flow perfusion in Zebrafish embryos, significantly. In addition, RT-PCR results showed that the NO-RPs significantly reduced the expression of pro-inflammatory markers (lL-6&COX-2) in the heart failure zebrafish model. …"
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CanCOVID‐19 mitigation measures promote telework practices? حسب Ammar Abulibdeh (15785928)

"…<p dir="ltr">The propagation of coronavirus disease 2019 (COVID-19) pandemic had resulted in a significant slowdown of economic activities worldwide. …"

A machine learning approach on chest X-rays for pediatric pneumonia detection حسب Barakat, Natali Imad

"…Thus, there is a significant need for automating the detection process to minimize the potential human error. …"
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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer حسب Christophe Michel Raynaud (17449906)

"…The use of a CRISPR-dCas9 UNISAM and KRAB system could increase or decrease SLFN11 expression significantly (up to fivefold), stably and specifically in BT-549 and T47D cancer cell lines. …"

In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model حسب Maram Hasan (6672440)

"…Our findings demonstrated that the NO-RPs improved the survival rate in the heart failure zebrafish model and reversed heart failure by enhancing blood flow perfusion in Zebrafish embryos, significantly. In addition, RT-PCR results showed that the NO-RPs significantly reduced the expression of pro-inflammatory markers (lL-6&COX-2) in the heart failure zebrafish model. …"

The Relationship between Smoking Cessation and Health Insurance Coverage: An Analysis of Cost Saving and Health Outcomes حسب Al Farhan, Nasser

"…The use of tobacco products remains a significant public health concern worldwide, with smoking being a leading cause of preventable death and disease. …"
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Challenges in child and adolescent health across the Arab Gulf countries—Focus on metabolic health حسب Basma Haris (12040355)

"…The combination of an increasing youth population combined with rapid modernisation, increasing per capita income and the paradigm shift towards unhealthy and affluent lifestyles has created a significant burden of non‐communicable diseases (NCDs), especially obesity and diabetes. …"

Type II diabetes mellitus and hyperhomocysteinemia حسب Platt, Daniel E.

"…Results We found that Hc levels were significantly reduced among subjects with diabetes compared to those without diabetes when adjusted for all potential confounders (OR 0.640; 95% CI [0.44–0.92]; p = 0.0200). …"
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The Prevalence and Genetic Spectrum of Familial Hypercholesterolemia in Qatar Based on Whole Genome Sequencing of 14,000 Subjects حسب Ilhame Diboun (3522413)

"…<p dir="ltr">Familial hypercholesterolemia (FH) is an inherited disease characterized by reduced efficiency of low-density lipoprotein-cholesterol (LDL-C) removal from the blood and, consequently, an increased risk of life-threatening early cardiovascular complications. …"

Efficacy and safety of aldafermin in non-alcoholic steatohepatitis: A systematic review and meta-analysis of randomized controlled trials حسب Mohamed Mahmoud Marey (18560902)

"…<h3>Background</h3><p dir="ltr">Non-alcoholic steatohepatitis (NASH) is an advanced subtype of non-alcoholic fatty liver disease (NAFLD). NASH prevalence is increasing exponentially and carries a high risk for disease progression, cirrhosis, and liver-related mortality. …"

On the benefits of sleep حسب Nature Research (16552612)

"…It is well known that sleep deprivation can significantly affect cognitive functions such as attention and memory. …"

Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model حسب Sahar Isa Da’as (18288880)

"…These knockout zebrafish displayed significant morphological heart alterations related to a significant decrease in ventricular and atrial diameters at systolic and diastolic states at the larval stages. …"

Safety and efficacy of ensifentrine in COPD: A systemic review and meta-analysis حسب Ambanna Yappalparvi (21260018)

"…<h3>Background</h3><p dir="ltr"><u>Chronic obstructive pulmonary disease </u>(COPD) significantly impacts global health due to persistent airflow limitation and inflammation. …"

Comparative Transcriptome Analysis Reveals That Exendin-4 Improves Steatosis in HepG2 Cells by Modulating Signaling Pathways Related to Lipid Metabolism حسب Khaoula Errafii (10914446)

"…We compared the transcriptome profiles of untreated steatotic, and Ex-4-treated steatotic cells, and used Ingenuity Pathway Analysis (IPA) to identify the signaling pathways and associated genes involved in the protective effect of Ex-4. Ex-4 treatment significantly reduces steatosis. RNA-seq analysis revealed 209 differentially expressed genes (DEGs) between steatotic and untreated cells, with farnesoid X receptor/retinoid X receptor (FXR/RXR) (p = 8.9 × 10⁻⁷) activation being the top regulated canonical pathway identified by IPA. …"

The characteristics of <i>CALR</i> mutations in myeloproliferative neoplasms: a clinical experience from a tertiary care center in Qatar and a literature review حسب Mostafa Najim (14150400)

"…</p><h3>Conclusion</h3><p dir="ltr">The data shows a significant rise in CALR-positive MPN diagnoses in younger people, emphasizing the need for a better assessment tool to improve disease management and reduce complications.…"

Factors associated with mental health outcomes among medical residents exposed to COVID-19 حسب Mohamed Adil Shah Khoodoruth (14722588)

"…However, data on the psychological impact of infectious disease outbreaks, and COVID-19 in particular, on medical residents are relatively lacking.…"

Challenges of morbid obesity in gynecological practice حسب Albert A. Opoku (17019078)

"…Obesity affects several aspects of health, with increased risks of cardiovascular disease, diabetes, metabolic syndrome, and several malignancies.…"

A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle حسب Sanjay Kumar (8853)

"…By examining the effects of glycosylation and other structural-activity relationships, the presence of sugar moiety in flavonoids significantly reduces its binding energy. It increases the solubility of flavonoids leading to reduced toxicity and higher bioavailability. …"

Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line حسب Toutounji, Mohamad

"…The present study investigates endoplasmic reticulum (ER) stress in addition to alterations in protein and membrane trafficking in a dextran sulfate sodium (DSS)-induced IBD-like phenotype of intestinal Caco-2 cells in culture. DSS treatment significantly reduced the transepithelial electric resistance (TEER) and increased the epithelial permeability of Caco-2 cells, without affecting their viability. …"
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