Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras by Charles W. Parry (20966154)

“…Activating mutations of Ras are one of the most prevalent drivers of cancer and are often associated with poor clinical outcomes. Despite FDA approval for two irreversible inhibitors that target the inactive state of KRas^G12C, significant unmet clinical need still exists, and the susceptibility of non-G12C mutants to inactive-state inhibition remains unclear. …”

Propofol anesthesia or with surgery decreased the expression of BDNF and p-TrkB, but SAHA reversed the reduction. by Yunlin Feng (3043659)

Depletion of EphA3 or EphA4 recovers the decreased ERK and Akt activation and lytic gene expression in RNF5 KO PEL cells. by Xiaojuan Li (351842)

IGF2BP3-RRM2 association. by Zhaonan Ban (18707733)

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Environmental enrichment reverses the social isolation induced changes in the expression of BDNF in hippocampus. by Swamynathan Sowndharya (17816808)

Social isolation induced alteration in expression of Bdnf variant reversed by environmental enrichment. by Swamynathan Sowndharya (17816808)

“…Real-time qPCR showing the expression of <b>(b)</b> Bdnf exon (III) level was increased, but <b>(d)</b> exon (IV) level was decreased by SI stress in STSC and LTSC housing condition, EE reversed the SI effect. …”

Environmental enrichment reverses the social isolation induced changes in the gut and brain metabolities. by Swamynathan Sowndharya (17816808)

Significant variables of DR association from univariate analyses. by Radhika Krishnan (15213756)

Nineteen SNPs with significant association (<i>P < </i>5 × 10⁻⁸) with risk on minJSW decrease in knee OA. by Mieke L. M. Bentvelzen (21594442)

“…<p>Nineteen SNPs with significant association (<i>P < </i>5 × 10⁻⁸) with risk on minJSW decrease in knee OA.…”

Associations between decreases in serum UA levels and functional outcomes at 3 months. by Kuniyuki Nakamura (13040299)

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Associations between decreases in serum UA levels and neurological outcomes during hospitalization. by Kuniyuki Nakamura (13040299)

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Top 10 significantly enriched Pfam annotations associated with each LCD category. by Sean M. Cascarina (8363391)

Top 10 hub genes associated with RA validated in GSE77298. by Zhaonan Ban (18707733)

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Comparison of questionnaire scores among genotypes for the significant associations. by Dai Nogimura (21445649)

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Tax expression is associated with decreased cellular motility. by Saumya Ramanayake (7879091)

Nasal microbiota features significantly associate with the presence of clinical signs. by Holly Kristin Arnold (14204655)

Gut microbiota features significantly associate with the presence of clinical signs. by Holly Kristin Arnold (14204655)

Factors associated with the <i>SS</i> Positives. by Anuradha Rajamanickam (5278013)

“…Additionally, a positive correlation between AGPTL levels and IgG suggested an association with immune activation. These findings suggest that Strongyloides infection is associated with elevated AGPTL levels, which decrease following effective treatment. …”

Environmental enrichment reverses the social isolation induced changes in phosphorylation of Dab-1 and Akt levels. by Swamynathan Sowndharya (17816808)

Environmental enrichment reverses the social isolation induced alteration in expression of Reelin, its receptors and SFK. by Swamynathan Sowndharya (17816808)