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Precision biomarker discovery in hypertension through explainable AI and proteomics
Published 2026“…We identified 36 proteins significantly associated with hypertension and observed a characteristic pattern featuring lower Renin, sRAGE, ghrelin, and IL-1RAcP, and higher TFPI, QORL1, HSP70, and C5a in hypertensive individuals. …”
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Integrating Genome Sequencing and Untargeted Metabolomics in Monozygotic Twins with a Rare Complex Neurological Disorder
Published 2024“…<p dir="ltr">Multi-omics approaches, which integrate genomics, transcriptomics, proteomics, and metabolomics, have emerged as powerful tools in the diagnosis of rare diseases. We used untargeted metabolomics and whole-genome sequencing (WGS) to gain a more comprehensive understanding of a rare disease with a complex presentation affecting female twins from a consanguineous family. …”
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183
The Role of Media Literacy in Countering Misinformation
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Analysis of 14,392 whole genomes reveals 3.5% of Qataris carry medically actionable variants
Published 2024“…Data on cardiovascular disease, cancer, and hypercholesterolemia allowed us to assess the disease-relevant phenotype association of rare missense variants. …”
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
Published 2021“…Amplification of MYC-N proto-oncogene is highly associated with clinically aggressive disease, recurrence and treatment failure. …”
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An Analysis of Thermal Comfort at the School Outdoor Spaces: A Case Study of the American School of Creative Science, Dubai, UAE
Published 2022“…Additionally, the addition of vegetation alone had an impact on the microclimate decreasing it by 5%. Thus, combining the strategies of vegetation, shade, green facades/roofs and small water features resulted in 5% to 25% reduction in PET depending on the corresponding location being analyzed. …”
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191
High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis
Published 2023“…Our statistical analysis has shown that significantly lower ROX index (5.07 ± 1.66, p = 0.028) and PaO2/FiO2 (100 ± 27.51, p = 0.031) are associated with HFNO failure, while a significantly lower respiratory rate (RR) (23.17 ± 4.167, p = 0.006) is associated with HFNO success. …”
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Characteristic MicroRNAs Linked to Dysregulated Metabolic Pathways in Qatari Adult Subjects With Obesity and Metabolic Syndrome
Published 2022“…Additionally, miR-652-3p’s differential expression correlated significantly with HDL and creatinine.</p><h3>Conclusions</h3><p dir="ltr">MicroRNAs associated with metabolic syndrome in obese subjects may have a pathophysiologic role and can serve as markers for obese individuals predisposed to various metabolic diseases like diabetes.…”
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On the benefits of sleep
Published 2015“…More recently, sleep disturbances have been linked to a wide variety of conditions, from psychiatric disorders such as depression to neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Disruptions in the circadian rhythm, or the “biological clock” of the body, are also associated with increased risk of cancer, heart disease, and metabolic disorders. …”
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High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis
Published 2023“…Our statistical analysis has shown that significantly lower ROX index (5.07 ± 1.66, p = 0.028) and PaO2/FiO2 (100 ± 27.51, p = 0.031) are associated with HFNO failure, while a significantly lower respiratory rate (RR) (23.17 ± 4.167, p = 0.006) is associated with HFNO success. …”
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195
Total and segmental liver volume variations
Published 2015“…Liver volume is measured with CT before living-donor liver transplantation or major hepatic resection in patients with and without chronic liver disease.3., 4., 5., 6., 7., 8., 9. and 10. This reproducible, noninvasive procedure is necessary because significant interpatient variation is believed to exist in the relative contributions of the hepatic segments to TLV.11 CT volumetry accurately predicts TLV on the basis of body surface area or body weight,12 which may achieve the true goal of preoperative CT volumetry of the liver, that is to estimate the individual patient's hepatic metabolic demands after resection or transplantation.7 Complications associated with technical aspects of liver surgery are decreasing, and focus has concurrently shifted to analysis of postoperative complications after major hepatic resection and liver transplantation on the basis of liver remnant volume and graft volume.3., 4., 6., 7., 8. and 13. …”
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Hydroxyurea Use in Lebanese Patients With [beta]-Thalassemia Intermedia
Published 2006“…The difference in response to HU between Lebanese and Iranian patients could be due to the heterogenous nature of the disease, resulting from different mutations, and the association between the types of mutations and the response to HU. …”
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Formation of Trihalomethanes during Seawater Chlorination
Published 2010“…Rapid decrease of UV absorbance at 254 nm was also observed during seawater chlorination which is indicative of natural organic matter degradation into small organic molecules including THMs and other by-products. …”
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Design and Development of Inexpensive Paper-Based Chemosensors for Detection of Divalent Copper
Published 2023“…High concentration of copper in blood serum and urine is associated with diseases like liver diseases, carcinomas, acute and chronic infections, rheumatoid arthritis, etc. …”
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Mining exposes Sudanese population to harmful pollutants
Published 2015“…A high blood plasma level of this is associated with a wide variety of diseases and conditions, including skin ulcers, lung cancer, brain damage, encephalitis, emphysema and bronchitis. …”