Clinical characteristics and outcomes of patients with TSH-secreting pituitary adenoma and Graves’ disease - a case report and systematic review by Adeel Ahmad Khan (14152953)

“…</p><h3>Conclusion</h3><p dir="ltr">TSHoma and GD can co-exist, and it is essential to identify this rare association as it can significantly impact treatment strategies.…”

Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing by Mohamad Saad (214545)

“…</p><h3>Methods</h3><p dir="ltr">We conducted a genome-wide association study for coronary heart disease in a Middle Eastern cohort using whole genome sequencing and assessed the performance of 6 PRSs developed with methods including LDpred (PGS000296), metaGRS (PGS000018), Pruning and Thresholding (PGS000337), and an EnsemblePRS we developed. …”

T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility by Hirbli, Kamal

“…Genome-wide association studies (GWAS) of multiple populations with distinctive genetic and lifestyle backgrounds are crucial to the understanding of Type 2 Diabetes Mellitus (T2DM) pathophysiology. …”
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Genome-Wide Association Study in a Lebanese Cohort Confirms PHACTR1 as a Major Determinant of Coronary Artery Stenosis by Hager, Jorg

“…The association was replicated in an additional 2,547 individuals (OR = 1.31, p = 8.85×10−6), leading to genome-wide significant association in a combined analysis (OR = 1.34, p = 8.02×10−10). …”
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Genome-wide association study and trans-ethnic meta-analysis identify novel susceptibility loci for type 2 diabetes mellitus by Asma A Elashi (18464133)

“…<h3>Background</h3><p dir="ltr">The genetic basis of type 2 diabetes (T2D) is under-investigated in the Middle East, despite the rapidly growing disease prevalence. We aimed to define the genetic determinants of T2D in Qatar.…”

National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050 by Marie, Ng

“…Without major reform, the forecasted trends will be devastating at the individual and population level, and the associated disease burden and economic costs will continue to escalate. …”
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Revisiting high-density lipoprotein cholesterol in cardiovascular disease: Is too much of a good thing always a good thing? by Mohammad Al Zein (20090700)

“…<p dir="ltr">Cardiovascular disease (CVD) continues to be a leading cause of global mortality and morbidity. …”

Household food insecurity and nutritional status of pre-school children following relaxation of corona virus disease-2019 (COVID-19) restrictions by Abdullah H., Anaqreh

“…Background & aimsStudies found a high prevalence of household food insecurity (HFI) and malnutrition and an association between them during the movement restriction period of the corona virus disease-2019 (COVID-19) pandemic. …”
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Exploring the Fecal miRNA Profile in FMF Patients and the Role of miR-21-5p in Inflammatory Pathways Associated with FMF Pathogenesis by Chaaban, Ahlam

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16S rRNA Gene-Based Characterization and Functional Profiling of the Microbiome in Young Adults by Makhlouf, Rita

“…The high observed Firmicutes to Bacteroidetes ratio and the dominance of Bacteroides over Prevotella are associated with a diet rich in fat and proteins. An increased Proteobacteria level was linked with gut dysbiosis and reported in Type 2 diabetes, metabolic disorders, and Inflammatory Bowel Disease (IBD). …”
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Efficacy and safety of ensifentrine, a novel phosphodiesterase 3 and 4 inhibitor, in chronic obstructive pulmonary disease: A systematic review and meta-analysis by Eeshal Fatima (18255772)

“…</p><h3>Conclusion </h3><p dir="ltr">Ensifentrine is associated with improvements in outcomes related to COPD symptoms such as peak FEV-1, morning trough FEV-1 and TDI in the patients suffering from this chronic disease. …”

An unusual presentation of invasive aspergillosis with submandibular swelling in a 49‐year‐old man with end‐stage renal disease: A case report by Phool Iqbal (12217770)

“…Our main aim is to highlight the significance of early diagnosis and management in such a rare presentation associated with a life-threatening condition like IA.…”

The Superiority of T2*MRI Over Serum Ferritin in the Evaluation of Secondary Iron Overload in a Chronic Kidney Disease Patient: A Case Report by Abdulrahman Al-Mashdali (16388474)

“…<p>Secondary iron overload is increasingly encountered in chronic kidney disease (CKD) patients because of the frequent use of parenteral iron products, especially in hemodialysis patients. …”

A comparison study of prevalence, awareness, treatment and control rates of hypertension and associated factors among adults in China and the United States based on national survey... by Xiaomin, Sun

“…Different from the US, obesity was negatively associated with hypertension control in China. ConclusionHypertension prevalence in China is similar to that in the US, but the control rate in China was significantly lower. …”
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The Effects of Social Determinants of Health on Cardiovascular Outcomes in Lebanese with Type 2 Diabetes by Saadé, Rita

“…Results in the bivariate analyses showed a significant associations (p<0.05) between waist circumference and the following variables in the demographics (age, school years, work hours, number of rooms, home owning, generator subscription as a source of electricity, public and car transportation, and diabetes family history), anthropometrics and other characteristics (weight, systolic blood pressure, BMI, A1C) and social determinants of health (health literacy and adverse childhood score ACE). …”
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Cryptosporidium spp., prevalence, molecular characterisation and socio-demographic risk factors among immigrants in Qatar by Sonia Boughattas (508422)

“…Conclusions/Significance Our results contribute to a better understanding of the epidemiology of cryptosporidiosis and the risk factors associated with the likelihood of carrying this infection among immigrant workers from developing countries.…”

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

“…In conclusion, serum 25(OH)D ≥75 nmol/L is associated with positive indicators related to cardiometabolic diseases in US adults.…”

A complex presentation of an uncommon disease: Gas-forming pyogenic liver abscess complicated by septic pulmonary emboli and muscle abscesses, a case report and review of the liter... by Aseel H. Alzibdeh (17317009)

“…The disease is associated with diabetes mellitus (DM) while Klebsiella penumoniae is the most frequently isolated pathogen. …”

Life-threatening arrhythmogenic CaM mutations disrupt CaM binding to a distinct RyR2 CaM-binding pocket by Angelos, Thanassoulas

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GLP-1 receptor agonists, are we witnessing the emergence of a paradigm shift for neuro-cardio-metabolic disorders? by Abdelilah Arredouani (10914455)

“…The <u>neuroprotective </u>attributes of GLP-1 RAs have garnered significant interest, with research indicating their potential to alleviate cognitive decline associated with <u>neurodegenerative diseases</u>. …”