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441
RFX3 is essential for the generation of functional human pancreatic islets from stem cells
منشور في 2025"…The loss of <i>RFX3</i> disrupted pancreatic endocrine gene regulation, reduced the number of hormone-secreting islet cells and impaired beta cell function and insulin secretion. Despite a significant reduction in the expression levels of pancreatic islet hormones, the pan-endocrine marker chromogranin A remained unchanged at both EP and islet stages, likely due to an increase in the abundance of enterochromaffin cells (ECs). …"
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442
Clinical reappraisal of the composite international diagnostic interview version 3.3 in Qatar's National Mental Health Study
منشور في 2024"…</p><h3>Results</h3><p dir="ltr">Initial CIDI prevalence estimates differed significantly from the SCID for most diagnoses ( X<sup>2</sup><sub>1</sub>= 6.6–31.4, p = 0.010 < 0.001), but recalibration reduced most of these differences and led to consistent increases in individual‐level concordance (AU‐ROC) from 0.53–0.76 to 0.67–0.81. …"
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443
Comparison of diesel emission experiments in view of the environment: A case study at Dubai
منشور في 2012"…The implementation of a diesel particulate filter lead to even better emission reductions but at a higher cost, with hydrocarbon emissions decreasing by 150%, carbon monoxide by 500% and nitrogen oxides by 700%. …"
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article -
444
Potential Biomarkers to Predict Acute Ischemic Stroke in Type 2 Diabetes
منشور في 2021"…PPBP and THBS1 tended to increase at hypoglycemia in both cohorts, though reached significance only in controls (p < 0.05), returning to BL levels post-hypoglycemia. …"
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445
Corporate Governance, Disclosure Content and Shareholder Value
منشور في 2013"…Banks market capitalisation dropped significantly, risk levels increased and stakeholders’ confidence was shaken. …"
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masterThesis -
446
Thymoquinone from Nigella sativa seeds promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer cells in vitro
منشور في 2016"…The reduction in proliferation was significantly dose- and time-dependent. After determining the best combination (40 µM thymoquinone and 0.6 µM topotecan), cell proteins were extracted after treatment, and the expression levels of B-cell lymphoma 2 and of its associated X protein, proteins p53 and p21, and caspase-9, caspase-3, and caspase-8 were studied by Western blot. …"
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article -
447
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448
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
منشور في 2024"…Single-cell analysis revealed high RFX6 expression levels in endocrine clusters across various hESC-derived pancreatic differentiation stages. …"
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449
Feeder protection challenges with high penetration of inverter based distributed generation
منشور في 2013"…The increasing proportion of inverter based distributed generation (DG) in the power system may limit the short circuit power available at distribution substations and consequently cause significant troubles for the protection of distribution feeders where DG are connected. …"
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conferenceObject -
450
A Brief Review on the Development Progress of High-Efficiency Klystrons
منشور في 2025"…The development of mathematical and computer models of beam-wave interactions in klystrons plays a pivotal role in significantly increasing the efficiency of these devices. …"
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451
Evaluation of waterpipe smoke toxicity in C57BL/6 mice model
منشور في 2020"…Our results mainly showed a significant increase in urea serum levels (+28%) in SE mice along with renal pathological damage in both SE and DE mice compared to CON. …"
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article -
452
Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patien...
منشور في 2023"…Non-responding patients showed a significant increase in exosomal-PD-L1 (p=0.0078). Furthermore, responding-patients without liver-metastasis showed significant-upregulation of PD-1 (p=0.0070), and downregulation of ULBP1 (p=0.0137) and Siglec-7 (p=0.0037). …"
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453
Psychological inoculation against problematic social media use among adolescents: An experimental study
منشور في 2025"…Results indicated a significant decrease in PSMU levels following active inoculation, particularly in withdrawal, persistence, displacement, and deception symptoms. …"
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454
Can Ease of Doing Business Shorten the Distance and Attract Foreign Direct Investment
منشور في 2021"…Using this measure, our results show that a favorable business climate has a significant moderating effect on the risks that a MNC faces when investing in countries with significantly different wealth levels. …"
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455
The Challenges of Corporate Governance Systems for Construction Project Management
منشور في 2014"…With the increasing levels of globalization resulting from liberalization of markets, efficient flow of information, and integration of economies, the industry is turning its attention to the global market. …"
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456
Essays on the effect of excess compensation and governance changes on firm value
منشور في 2012"…We show that, on average, the director actual compensation level is above the efficient compensation level by around 63%. …"
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masterThesis -
457
Preterm birth in low-middle income Countries
منشور في 2024"…Although the overall trend is decreasing, this is mainly in high-income countries (HIC). …"
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article -
458
Redox Homeostasis and Inflammation Responses to Training in Adolescent Athletes: a Systematic Review and Meta-analysis
منشور في 2020"…</p><h3>Conclusions</h3><p dir="ltr">The results showed significant alterations in oxidative stress and cytokine levels after acute exercise, ranging from moderate to extremely large. …"
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459
Predictive Power of Random Forests in Analyzing Risk Management in Islamic Banking
منشور في 2024"…Concerns related to terrorism financing and cybersecurity risks have also decreased due to the better enforcement of anti-money laundering regulations and investments in cybersecurity infrastructure and education. …"
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460
The Impact of Absenteeism and Islamic Work Ethics on Project Delivery in Public Projectized Organizations in the United Arab Emirates (UAE)
منشور في 2019"…As the modern world demands a lot from the employees so the stress levels of the employees were increased and are not able to balance the work and the personal life where the individual is affected physically and psychologically that leads to employee’s absenteeism. …"
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