Supplementary file 1_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.pdf حسب Shengyou Song (22391068)

"…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…"

Table 1_Xianyu capsule ameliorates neuroinflammatory and glycerophospholipid metabolism in lithium-pilocarpine-induced acute epilepsy.docx حسب Dongsheng Yu (521989)

"…Objective<p>Xianyu capsule (XYC) is a commonly used traditional Chinese medicine in the clinical treatment of epilepsy, with significant curative effect and good safety. However, its mechanism of action remains poorly understood. …"

Table 1_Association between composite dietary antioxidant index and increased urinary albumin excretion: a population-based study.docx حسب Shaopeng Li (820947)

"…The prevalence of increased ACR decreased across the CDAI quartiles from 13.89% in Q1 to 10.11% in Q4. …"

Table 1_Sex disparities in the risk of intracranial aneurysm rupture: a case–control study.docx حسب Dong Shen (485693)

"…In the subgroups based on the covariates used in this study, we only identified statistically significant interaction between sex and age. Although ruptured IAs were most common in males and females aged 50–59 and 60–69 years, respectively, risk of IA rupture peaked at ages 30 and 30–50 years in females and males, respectively, and decreased with age in both sexes.…"

Table 1_Leucocalocybe mongolica inoculation enhances rice growth by reallocating resources from flavonoid defense to development via MYB/bHLH/WRKY networks.xlsx حسب Mingzheng Duan (11630632)

"…However, total flavonoid content decreased at the highest LY9 concentration, suggesting a metabolic trade-off between growth promotion and secondary metabolite production. …"

Table 2_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.xlsx حسب Maxim Sorokin (4379848)

"…We detected no statistically significant difference in the number of chimeric transcripts in FFPE and FF RNAseq profiles. …"

Image 2_Hippocampus-sparing volume-modulated arc therapy in patients with World Health Organization grade II glioma: a feasibility study.jpeg حسب Renxian Xie (17044863)

"…Notably, HS VMAT plans markedly decreased doses to the ipsilateral hippocampus and the contralateral hippocampus, demonstrating its efficacy in hippocampal dose reduction.…"

Table 1_DKK3 and SERPINB5 as novel serum biomarkers for gastric cancer: facilitating the development of risk prediction models for gastric cancer.docx حسب Yan-Yu Liu (9562262)

"…A total of 530 participants aged 40 to 74 were analyzed, with 104 ultimately diagnosed with GC. Significant biomarkers in GC patients were identified by DIA combined ELISA, including elevated Keratin 7 (KRT7) and Mammary fibrostatin (SERPINB5) (P<0.001) and decreased Dickkopf-associated protein 3 (DKK3) (P<0.001). …"

Table 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx حسب Mattia Dalle Nogare (22696022)

"…</p>Results<p>CIBERSORTx demonstrated the highest sensitivity (r > 0.85) for detecting pituitary cell types, although accuracy decreased for TME components. Application to ten GH-secreting PitNETs with known histological contamination and to public datasets consistently revealed residual normal tissue across hormone-secreting subtypes, excluding silent tumors. …"

Table 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.docx حسب Thibaud Dauphin (21196820)

"…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …"

Table 1_Intergenerational education mobility in India: nonlinearity and the Great Gatsby Curve.docx حسب P. K. V. Kishan (19744606)

"…</p>Results<p>Our analysis reveals a high degree of intergenerational persistence in education, although this persistence has decreased over time. Employing quantile regressions, we observe significant nonlinearities in the relationship between fathers’ and sons’ educational outcomes across the educational distribution. …"

Data Sheet 6_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... حسب Ying-han Deng (21604157)

"…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…"

Image 3_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif حسب Inssaf Berkiks (15350248)

"…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …"

Data Sheet 1_Danqi soft caspule alleviates myocardial ischemia-reperfusion injury induced cardiomyocyte apoptosis by attenuating mitochondrial fission.docx حسب Ye Yang (297214)

"…Background<p>Myocardial ischemia-reperfusion (I/R) injury which leads to continuously worsening ventricular remodeling and cardiac dysfunction in the chronic stage, is a significant contributor to the global prevalence of heart failure. …"

<b>Differential Effects of Retinol-Binding Protein 3 and Anti-VEGF Antibodies on Retinal Dysfunctions in Diabetic Retinopathy</b> حسب Qin Li (36669)

"…<p dir="ltr">Anti-vascular endothelial growth factor (anti-VEGF) therapies are effective treatment of severe diabetic retinopathy (DR) and macular edema, but a significant subset of people showed inadequate response to anti-VEGF intervention. …"

Table 2_Evaluating treatment and care outcomes for neuromuscular diseases in a pediatric intermediate care setting.docx حسب Giacomo Brisca (10963929)

"…The majority of admissions were due to neurological issues (39.7%) and respiratory complications (22%), with a significant proportion of patients requiring initiation or potentiation of respiratory support (59%). …"

<b>Social conditions alter the growth, metabolic rate, behavioral traits, and food-shelter preferences in the qingbo </b><b><i>Spinibarbus sinensis</i></b> حسب Yu-Lin Zhang (9129227)

"…Group effects from conspecifics during rearing and testing led to increased activity and decreased sociability in qingbo, whereas the presence of conspecifics during testing increased boldness. …"

Supplementary file 1_Assessment of suitability evaluation for Ficus altissima blume ancient trees in different climatic environments in Guangxi, China.docx حسب Hongliang Gu (21671054)

"…Introduction<p>The Guangxi Zhuang Autonomous Region of China is home to numerous Ficus altissima Blume (F. altissima) ancient trees over 300 years old, which hold significant cultural, ecological, and scientific research value. …"

Data Sheet 3_Duodenal obstruction due to two congenital bands: a case report and literature review.pdf حسب Shiqiu Xiong (238109)

"…Physical examination revealed abdominal tenderness and decreased bowel sounds. Contrast x-ray showed an obstructed passage of contrast through the third part of the duodenum. …"

Image 5_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tiff حسب Inssaf Berkiks (15350248)

"…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …"