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Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase
Published 2022“…We demonstrate here that dex significantly upregulates TDO in A375, a more aggressive melanoma cell line, confirming that dex effects are not limited to SK-Mel-28 cells. …”
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322
Acoustically activated release of estrone-targeted liposomes used for breast cancer treatment
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323
Molecular forces driving protein complexation of lentil and whey proteins: Structure-function relationships of trehalose-conjugated protein complexes on protein digestibility and s...
Published 2024“…Due to these modifications on the protein structures, the protein digestibility (80–86%) and water solubility (90–94.5%) of T-LWPs increased significantly (P < 0.05) with the increase in the trehalose concentration, from 0 (control) to 5% (w/w), respectively. …”
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324
Is embolization of segment 4 portal veins before extended right hepatectomy justified?
Published 2008“…Results After a median of 27 days, the S2+3 volume increased significantly after both RPVE and RPVE+4, but the absolute increase was significantly higher for RPVE+4 (median, 106 mL vs 141 mL; P = .044), as was the hypertrophy rate (median, 26% vs 54%; P = .021). …”
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325
Accelerated dissolution testing for controlled release microspheres using the flow-through dissolution apparatus
Published 2008“…The effect of increased temperature was determined to be the statistically significant variable.…”
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326
Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy
Published 2023“…Of these, a chemotherapeutic demethylating agent, Decitabine (DAC), has been reported to induce a dual effect on both DNA demethylation and histone changes leading to an increased expression of target biomarkers, thus making it an attractive anti-tumorigenic drug.…”
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327
Emerging therapies in multiple myeloma
Published 2015“…However, despite the increased effectiveness of the first-line agents, the majority of patients will eventually relapse and become drug resistant. …”
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328
Enhancing human thermal comfort in hot arid cities: A systematic review of urban heat island observations and mitigation strategies
Published 2025“…<p dir="ltr">The urban heat island (UHI) effect significantly impacts cities' thermal environments, especially in hot arid regions (Köppen-Geiger: <i>BWh</i>), where rapid urbanization has intensified heat stress. …”
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Friction Reduction in Elastohydrodynamic Contacts by Thin Layer Thermal Insulation
Published 2014“…The presented simulations, validated by experiments, show that applying a thin DLC coating to metal surfaces creates an insulating effect that due to the increased liquid lubricant film temperature at the center of the contact, locally reduces lubricant viscosity and thus friction. …”
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330
Competition, regulation, and systemic risk in dual banking systems
Published 2024“…Interestingly, this effect is not significantly different between IBs and CBs. …”
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331
Occupational Violence at Lebanese Emergency Departments
Published 2011“…Exposure to verbal abuse was associated with serious outcomes including significantly higher levels of occupational burnout and an increased likelihood to quit current job. …”
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332
Board independance and the efficiency of internal capital markets
Published 2017“…We investigate the effect of increased board independence on the efficiency of internal capital markets in diversified firms. …”
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333
Local arterial vasoconstriction induced by octreotide in patients with cirrhosis
Published 2000“…Octreotide has a local vasoconstrictive effect that seems nitric oxide (NO)-independent. Octreotide probably has a facilitating effect over vasoconstrictors increased in chronic liver diseases…”
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334
Synthesis and Evaluation of Copper-Supported Titanium Oxide Nanotubes as Electrocatalyst for the Electrochemical Reduction of Carbon Oxide to Organics
Published 2019“…The addition of TNT significantly increased the catalytic activity of electrocatalyst for ERC. …”
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335
Solar cultivation of microalgae in a desert environment for the development of techno-functional feed ingredients for aquaculture in Qatar
Published 2022“…Biomass productivities increased significantly, during extreme seasons due to respective cooling and heating of the culture. …”
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336
Depression in migrant workers and nationals of Qatar: An exploratory cross-cultural study
Published 2019“…</p><h3>Results</h3><p dir="ltr">The odds of depression were significantly increased in LMs (OR = 3.31, 95% CI = 2.36–4.65) and WCMs (OR = 1.40, 95% CI = 1.04–1.90) compared with non-migrants. …”
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Can the Salivary Microbiome Predict Cardiovascular Diseases? Lessons Learned From the Qatari Population
Published 2021“…Linear Discriminant Analysis Effect Size (LEfSe) analysis revealed that Clostridiaceae and Capnocytophaga were the most significantly abundant genera in the LR group, while Lactobacillus and Rothia were significantly abundant in the HR group. …”
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Factors associated with functional disability among Lebanese elderly living in rural areas
Published 2018“…Chronic diseases, nutrition, and socioeconomic status also had a large effect on disability. Skin ulcer (ORa = 8.569; CI 5.330-14.823), followed by dementia (ORa = 3.667; CI 1.167-8.912), and anti-gout drugs (ORa = 3.962; CI 1.290-7.622) were found to be significantly associated with increased odds of disability the most. …”
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340
Combining Saliency with Prediction for Endoscopic Diagnosis
Published 2020Get full text
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