A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase by Ahmed S. Ibrahim (10049522)

“…The permeability effect of 12-HETE was significantly reduced in NOX2^−/− mice compared with the WT mice. …”

12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase by Amira Othman (380131)

“…VEGF-R2 inhibitor reduced the permeability effect of 12-HETE. Treatment of REC with HETE also increased ROS generation and expression of NOX2 and pVEGF-R2 and decreased pSHP1 expression. …”

Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling by Md Mizanur Rahman (14603354)

“…HFD also significantly increased the number of adipocytes in the bone marrow microenvironment of WT mice as compared to KO mice. …”

Diabetes mellitus and renal failure by Aoun, S.

“…Diabetes mellitus and end-stage renal disease are two pathologic entities associated with increased cardiovascular risk. Several studies have shown that arterial stiffness is increased in both cases and contributes to the increased risk. …”
Get full text
Get full text
Get full text
Get full text

An additive manufacturing approach based on electrohydrodynamic printing to fabricate P3HT:PCBM thin films by Zulfikre Esa (19457344)

“…As the annealing temperature and the flow rate were increased, discernible alterations in the PCBM clusters were consequently observed in the blends of the film and the size of the PCBM clusters has decreased by 3% while the distance between them was highly reduced by as much as 82%.…”

Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling by Crystal M. Ghantous (14571292)

“…Mechanical stretch significantly increased p-ERK1/2 after 10 minutes, whereas APN significantly reduced stretch-induced ERK1/2 phosphorylation. …”

Using Social Network Analysis to Study Business Partnerships by KARIM, ROLA RASHAD ARIF ABDUL

“…Social network analysis is gaining increased interest due to the expansion of social media and networking websites. …”
Get full text

Asphalt modification with polyphosphoric acid by Bazi, Gabriel

“…Another significant finding is that binders treated with polyphosphoric acid show increased resistance to oxidative aging, as measured by the pressure-aging vessel. …”
Get full text
Get full text
Get full text

Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway by Olfa Khalifa (10914452)

“…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …”

The Paget's disease of bone risk gene <i>PML</i> is a negative regulator of osteoclast differentiation and bone resorption by Sachin Wani (11704868)

“…The differentiation, survival and resorptive activity of osteoclasts prepared from Pml−/− mice was increased compared with wild type. Furthermore, the inhibitory effect of IFN-γ on osteoclast formation from Pml−/− was significantly blunted compared with wild type. …”

AI Integration Within the Architectural Design Process and Management, and its Influence on Project Agility: A Literature Review, Bibliometric, and Survey Analysis by MANSOUR, ABDULHAK N

“…The findings reveal that AI integration significantly enhances project agility and outcomes, primarily through increased design creativity and automation in project management. …”
Get full text

Acute exposure to cigarette smoking followed by myocardial infarction aggravates renal damage in an In vivo mouse model by Kobeissy, Firas

“…Finally, reactive oxygen species (ROS) production was significantly accentuated in S+MI group concomitant with a significant increase in NOX-4 protein levels. …”
Get full text
Get full text
Get full text
Get full text

Influence of Cognitive Bias on Decision Making in Mega Projects by ALNUAIMI, WALEED

“…Since mega projects are increasing in size and number, and their poor performance has been consistent despite various proposals suggested based on project management best practices that have mainly focused on the technical element of implementing mega projects, the performance in mega projects has not improved prompting this study to focus on optimism bias and strategic misrepresentation where if optimism is exceeded, it is termed as over optimism and leads to cost overrun due to significant underestimation of costs. …”
Get full text

Assessing the role of Environmental Legislation in Mitigating Climate Risk in GCC: A quantile ARDL approach by Mohamed Sami Ben Ali (23073832)

“…Using the panel Quantile ARDL technique, the findings suggest that climate legislation effectively mitigates climate risk. This effect is notably increased at the upper quantile in the long run. …”

Baroreflex control of renal sympathetic nerve activity during air-jet stress in rats by Kanbar, Roy

“…The latter effect was secondary to an increase (P < 0.01) in the range of the RSNA variation from 285 ± 33 to 619 ± 59 NU. …”
Get full text
Get full text
Get full text
Get full text

Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk by Merhi, Mahmoud

“…Results rs4769874 (ALOX5AP), rs854560 (PON1), and rs4646903 (CYP1A1 MspI polymorphism) are significantly associated with an increased risk of CAD with respective odds ratios of 1.53703, 1.67710, and 1.35520; the genetic variant rs9579646 (ALOX5AP) is significantly associated with a decreased risk of CAD (OR 0.76163). …”
Get full text
Get full text
Get full text

Local Over-Expression of VEGF-DDNDC in the Uterine Arteries of Pregnant Sheep Results in Long-Term Changes in Uterine Artery Contractility and Angiogenesis by Abi Nader, Khalil

“…There was a tendency to higher UABF in Ad.VEGF-DΔNΔC compared to Ad.LacZ transduced UtAs (50.58% v/s 26.94%, p = 0.152). There was no significant effect on maternal haemodynamics. An increased number of proliferating endothelial cells and adventitial blood vessels were observed in immunohistochemistry. …”
Get full text
Get full text
Get full text
Get full text

A comparison of peer, teacher and self-feedback on the reduction of language errors in student essays by Diab, Nuwar Mawlawi

“…Comparison of students' performance on pronoun agreement errors revealed that all groups increased the percentage of this error on the immediate post-test but decreased it on the delayed post-test, with no significant difference between the groups. …”
Get full text
Get full text
Get full text
Get full text

High phosphorus diet mitigates impairments in lipid and glucose metabolism associated with diet-induced obesity in male sprague dawley rats by Bassil, Maya

“…High fat induced obesity significantly (p<0.05) increased serum cholesterol, triglycerides and ALP in HF group (46.1±3.9mg/dl, 38.8±4.4mg/dl and 192.8±55.9U/l, respectively) compared to control (19.8±2.7mg/dl, 26.0.1±3.7mg/dl and 76.6±7.3U/l, respectively) but P supplementation in HFHP prevented this increase. …”
Get full text
Get full text
Get full text

A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters by Abdelrahman M. Awad (16932519)

“…The drill pipe rotation has the dominant effect on the performance of cuttings transportation, with the effect are more pronounced for highly deviated and horizontal wells. …”