BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells حسب Ali Alhoshani (3720718)

"…This effect was associated with a significant increase in the percentage of apoptotic MDA-MB-231 cells and in the expression of the apoptotic genes, caspase 3, caspase 7, and BAX, with inhibition of antiapoptotic gene, BCL-2 levels. …"

Radiation treatment outcomes for unresectable hepatocellular carcinoma حسب Skinner, Heath

"…One-year overall survival in patients treated to a biologically effective dose <75 was significantly lower than in patients treated to a biologically effective dose ≥75 (18% vs. 69%). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Exploring environmental, social, and governance and bank performance in the Gulf Cooperation Council region حسب Jaywant Michael (17541642)

"…The significant Hausman test favored using the fixed effect results. …"

Liquid Fuel Production from Pyrolysis of Waste Tires: Process Simulation, Exergetic Analysis, and Life Cycle Assessment حسب Altayeb, Ryan K.

احصل على النص الكامل

Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: a systematic review حسب Maged S. Alhammadi (14150757)

"…Regarding the vertical jaw relation, one study reported a significant decrease in mandibular plane inclination in OC and a significant increase in OOS. …"

Enhancing the Main Contractor-Subcontractor trusting relationship in the United Arab Emirates: A strategic approach to rebuilding trust in complex construction projects حسب ISSA, RAMAZ SELMAN

"…The oil price drop has significantly affected complex construction projects in the United Arab Emirates. …"
احصل على النص الكامل

Can Ease of Doing Business Shorten the Distance and Attract Foreign Direct Investment حسب AL KHOORI, YOUSUF

"…Using this measure, our results show that a favorable business climate has a significant moderating effect on the risks that a MNC faces when investing in countries with significantly different wealth levels. …"
احصل على النص الكامل

Strain response of hot-mix asphalt overlays for bottom-up reflective cracking حسب Ghauch, Ziad G.

"…The occurrence of reflective cracking under the combined effect of traffic and environmental loading significantly reduces the design life of the HMA overlays and can lead to its premature failure. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Ghost-NeRV: Efficient Neural Video Representation via Ghost Convolutions حسب Shanableh, Tamer

"…Unlike binarization-based approaches, Ghost-NeRV preserves full-precision computation while significantly reducing the number of floating-point operations and model parameters. …"
احصل على النص الكامل

Cognitive Vigilance Enhancement using Audio Stimulation of Pure Tone at 250 Hz حسب Yahya, Fares

"…The entropy measures show that the temporal profile of the EEG signals has significantly increased with VE. The classification results showed that SVM technique with DE features across all frequency bands can detect VE levels with accuracy varying between (92.10±02.24)% to (98.32±01.14)%, sensitivity of (92.50±02.33)% to (98.66±01.00)%, and specificity of (91.70±02.32)% to (97.99±01.05)%. …"
احصل على النص الكامل

Link between Transformational Leadership and Organizational Efficiency & Employee Performance حسب ALALI, ABDULLA HASSAN

"…Besides, it was found that TL further significantly influences employee performance in the UAE’s engineering and construction sector. …"
احصل على النص الكامل

The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar حسب Komal Rafique (17075074)

"…</p> <h3>Conclusion</h3> <p>The results of this study suggest that in women with additional risk factors for FGR, the concurrent use of metformin significantly decreases the birthweight and increases the risk for LBW, SFD, PTB and admission to NICU. …"

Modeling of photovoltaic soiling loss as a function of environmental variables حسب Wasim Javed (6105866)

"…Higher WS typically favored more positive daily ΔCI when RH was low, but at higher RH levels (>50%) daily ΔCI was more likely to be negative with increasing WS. In fact, high RH levels were related to negative daily ΔCI only at higher WS levels (>2ms−1); at lower WS levels RH had no significant effect on daily ΔCI. …"

Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans حسب Kirti S. Prabhu (4246144)

"…We also found that BTZ exerted its antitumor effects by generating reactive oxygen species (ROS), as blocking ROS production significantly reduced BTZ-induced apoptotic cell death. …"

A numerical model for the solution of thermal elastohydrodynamic lubrication in coated circular contacts حسب Habchi, Wassim

"…These effects increase with coating's thickness.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…Results: When applied separately, topotecan and andrographolide both exhibited anti-proliferative effects in a dose-dependent manner. Cotreating the cells with both topotecan and andrographolide simultaneously at various concentrations did not result in any significant changes. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Impact of School Leaders and Teachers in Empowering Students Towards NWEA MAP Assessment Attainment: A Study in a Private School in Dubai حسب KHUNDUQJI, RULA AREF

"…The findings indicate that transformational leadership fosters high student expectations and participation, while distributed leadership promotes shared decision-making among teachers, significantly influencing and boosting MAP results. Additionally, increased access to technology platforms also played a significant role and improved performance. …"
احصل على النص الكامل

Estimation of power grid topology parameters through pilot signals حسب Hargossian, H.

"…The distribution grid has been the source of an increased amount of electricity production in recent years. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The changing face of Qatar حسب Nature Research (16552612)

"…Although Qatar has seen a significant improvement in under-five and maternal mortality rates, and lowest rates of communicable disease and all-cause mortality rates, it has an extremely high prevalence of obesity, and this is continuing to increase. …"

Intratumoral FoxP3⁺Helios⁺ Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer حسب Azharuddin Sajid Syed Khaja (19720114)

"…Levels of CD4⁺FoxP3⁺Helios⁺ Tregs were significantly increased in the TME. Furthermore, we observed increased levels of PD-1/CTLA-4 and PD-1/CD39 co-expressing cells within FoxP3⁺Helios⁺ and FoxP3⁺Helios⁻ Treg subsets, indicative of their potent immunosuppressive potential. …"