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521
The promise of tirzepatide: A narrative review of metabolic benefits
Published 2025“…<p>Obesity and type 2 diabetes mellites (T2DM) are intertwined epidemics that continue to pose significant challenges to global public health. We aim to review the available evidence on the metabolic effects of tirzepatide, focusing on weight loss and maintenance of lost weight, body composition alterations, appetite regulation, glycemic control, and lipid profile modulation. …”
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522
Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema
Published 2010“…The effects of increased endogenous ceramides could be offset by sphingosine 1-phosphate (S1P), a prosurvival by-product of ceramide metabolism. …”
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523
A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells
Published 2008“…Although WP1066 did not induce immunological memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (TGF-β, RANTES, MCP-1, VEGF), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …”
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524
A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce...
Published 2008“…Although WP1066 did not induce immunologic memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (transforming growth factor-β, RANTES, MCP-1, vascular endothelial growth factor), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …”
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525
Insulin detemir in combination with oral antidiabetic drugs improves glycemic control in persons with type 2 diabetes in Near East countrie
Published 2017“…The percentage of persons who achieved the target of HbA1c<7% increased from .7% at baseline to 39% at week 24. Mean FPG decreased significantly from 213.7 ± 60.1 mg/dL to 120.3 ± 25.7 mg/dL (P<.001), and mean PPG from 271 ± 65.3 mg/dL to 158.1 ± 36.4 mg/dL (P<.0001). …”
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526
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527
Quantified Database for Methane Dehydroaromatization Reaction
Published 2022“…There is an increasing interest in this reaction evident by a large number of literature and patents published so far. …”
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528
Tuning dual-Fe sites in Fe–N–C dual-atom catalysts by sulfur doping for enhanced CO₂ electroreduction: Insights from the first-principles computations
Published 2025“…Sulfur incorporation significantly modifies the local electronic environment, notably increasing the density of states near the Fermi level and enhancing charge redistribution at the active sites. …”
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529
Endocrine contribution to the sexual dysfunction in patients with advanced chronic kidney disease and the role of hyperprolactinemia
Published 2021“…Patients treated with cabergoline (<i>n</i> = 26) showed a significant increase in LH levels (<i>p</i> = .003) and a significant decrease in prolactin levels (<i>p</i> = .003). …”
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530
The Use of Culturally-Familiar Literature in the EFL Classroom
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doctoralThesis -
531
On-demand mobile sensing framework for traffic monitoring. (c2017)
Published 2017“…With the increased need for mobility and the overcrowding of cities, the area of Intelligent Transportation aims at improving the efficiency, safety, and productivity of transportation systems by relying on communication and sensing technologies. …”
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masterThesis -
532
Enhanced catalytic ozonation of ibuprofen using a 3D structured catalyst with MnO<sub>2</sub> nanosheets on carbon microfibers
Published 2021“…The enhanced performance with the new catalyst could be attributed to its significantly increased available surface active sites and improved mass transfer of reaction media, as a result of the special surface and structure properties of this new three-dimensional network-structured catalyst. …”
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533
Optical pavement treatments and their impact on speed and lateral position at transition zones: A driving simulator study
Published 2021“…Results showed that pavement markings combining size and brightness manipulations were the most effective treatment, keeping drivers' traveling speed significantly below the traveling speed recorded in the untreated control condition. …”
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534
Ethnic-specific association of amylase gene copy number with adiposity traits in a large Middle Eastern biobank
Published 2021“…Indeed, lower AMY1 CN was associated with increased total and trunk fat percentages in Arabs (P < 4.60 × 10−3) but not in Persians. …”
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535
Polysaccharide nanocomposites in wastewater treatment: A review
Published 2024“…<p>In modern times, wastewater treatment is vital due to increased water contamination arising from pollutants such as nutrients, pathogens, heavy metals, and pharmaceutical residues. …”
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536
Neutrophil‐to‐Lymphocyte Ratio Predicts Dialysis Timing & Prognosis in Critically Ill Patients
Published 2025“…</p><h3>Results</h3><p dir="ltr">Elevated NLR levels were significantly associated with increased in‐hospital mortality. …”
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537
Stemming cardiovascular diseases in Qatar
Published 2015“…The importance of diabetes as a risk factor, however, was found to be higher than other countries in the Gulf region and significantly higher than the US.</p><p>“Public health officials should design programmes to improve the prevention, diagnosis, and management of risk factors such as diabetes and hypertension,” says Christos, as well as work on effective awareness campaigns to create a culture of preventive health in Qatar.…”
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538
The safety of outpatient total shoulder arthroplasty: a systematic review and meta-analysis
Published 2022“…<h2>Purpose</h2> <p>To meet the increasing demands of total shoulder arthroplasty (TSA) while reducing its financial burden, there has been a shift toward outpatient surgery. …”
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539
The Use of Transferrin and Ultrasound in Cancer Treatment
Published 2019Get full text
doctoralThesis -
540
Exercise training-induced speeding of VO<sub>2 </sub>kinetics is not intensity domain-specific or correlated with indices of exercise performance
Published 2024“…</p><h3>Results</h3><p dir="ltr">There was a significant time effect for the time constant (τ VO<sub>2</sub> ) between PRE (31.6 ± 10.4 s) and MID (22.6 ± 6.9 s) (p < 0.05) and PRE and POST (21.8 ± 6.3 s) (p < 0.05), but no difference between MID and POST (p > 0.05) and no group or interaction effects (p > 0.05). …”