Modulation of SLFN11 induces changes in DNA Damage response in breast cancer حسب Christophe Michel Raynaud (17449906)

"…The use of a CRISPR-dCas9 UNISAM and KRAB system could increase or decrease SLFN11 expression significantly (up to fivefold), stably and specifically in BT-549 and T47D cancer cell lines. …"

A Comprehensive Method of Ion Exchange Resins Regeneration and Its Optimization for Water Treatment حسب Al-Asheh, Sameer

"…The amount of resin significantly impacts the deionization efficiency; more ions are removed as the amount of resin increases.…"
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Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway حسب Kirti.S. Prabhu (17191231)

"…<p dir="ltr">Effective treatment of lung cancer remains a significant clinical challenge due to its multidrug resistance and side effects of the current treatment options. …"

Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress حسب Jing Ma (24574)

"…The concentration of malondialdehyde (MDA) and Cd accumulation (roots and shoots) increased significantly (P < 0.05) under the increasing levels of Cd in all genotypes of B. oleracea while antioxidant (enzymatic or non-enzymatic) capacity and nutritional status of the plants was decreased with varying levels of Cd in the sand. …"

Project Productivity vs. Health & Safety حسب Wilson, Stephen

"…It was found in both cases that the improved safety management approaches had a great effect on the workforce both in improving accident reporting statistics matched by significant gains in productivity. …"
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Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways حسب Daaboul, Hamid E.

"…HC treatment also had antitumor effect in vivo with no significant toxicity to laboratory mice.…"
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Serviceability and Flexural Behavior of Concrete Beams Reinforced with Basalt Fiber-Reinforced Polymer (BFRP) Bars Exposed to Harsh Conditions حسب Alkhraisha, Hakem

"…Test results also indicate that increasing the reinforcement ratio did not result in a directly proportional increase in the moment capacity. …"
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p53 Inhibition in Pancreatic Progenitors Enhances the Differentiation of Human Pluripotent Stem Cells into Pancreatic β-Cells حسب Idil I. Aigha (14913774)

"…Inhibition of p53 using pifithrin-μ (PFT-μ) at the MPC stage resulted in a significant increase in the number of PDX1+/NKX6.1+ cells and a reduction in the number of CHGA+/NKX6.1− cells. …"

Phosphorus supplementation recovers the blunted diet-induced thermogenesis of overweight and obese adults حسب Bassil, Maya S.

"…Overweight/obese subjects had a blunted DIT with placebo, while P supplementation induced a 23% increase in their DIT area under the curve (p < 0.05), which was associated with a significant increase in carbohydrate oxidation. …"
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Immune Checkpoints in Circulating and Tumor-Infiltrating CD4+ T Cell Subsets in Colorectal Cancer Patients حسب Salman M. Toor (8854751)

"…We also investigated correlations between the levels of different CD4⁺ T cell subsets and the clinicopathologic features including disease stage and tumor budding. We found a significant increase in the levels of CD4⁺FoxP3⁺Helios⁺ T cells, which represent potentially highly immunosuppressive Tregs, in the CRC TME. …"

Cushion plants act as facilitators for soil microarthropods in high alpine Sweden حسب Peter Ľuptáčik (14150913)

"…Cushion plants play an important role in supporting the biodiversity of soil fauna in severe alpine environments, with the positive effects of cushion plants increasing with environmental severity.…"

Factors Affecting Patients’ Use of Electronic Personal Health Records in England: Cross-Sectional Study حسب Alaa Abd-Alrazaq (17430900)

"…PE significantly mediated the effect of EE and PPS on BI (beta=.19, P<.001 and beta=.28, P=.001, respectively). …"

Beyond the needle: How nonsurgical management transforms foot and ankle ability in male footballers with posterior ankle impingement- a longitudinal study حسب Gupta, Jyoti

"…Tenderness and ROM showed significant changes after 4 and 8 weeks. The FAAM% score significantly increased (p < 0.001) after 8 weeks, reflecting enhanced overall functional ability. …"
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The role of protected areas in modulating vegetation response to climatic stressors in hyper-arid ecosystems حسب Ammar Abulibdeh (15785928)

"…Results show that vegetation sensitivity to climate drivers increased significantly post-protection. For example, in Al Reem, the effect of evaporation on NDVI shifted from a non-significant, 28.1 (p = 0.136) before 2006 to a significant, 18.5 (p = 0.007) after protection, while the number of precipitation events lost its prior significance (β = 3.4, p = 0.016 → p = 0.981). …"

Eradication of hepatitis C virus infection in kidney transplant recipients using direct‐acting antiviral therapy: Qatar experience حسب Mohamad M. Alkadi (14778640)

"…In the pre-direct-acting antiviral (DAA) era, treatment of HCV infection was associated with low response rates, poor tolerance, and increased risk of allograft rejection. However, DAAs have revolutionized HCV treatment. …"

Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults حسب Khaddaj, Rashel

"…Furthermore, the change between both groups was significantly different (-7.61 ±4.03 in the Vitamin D group, -3.50±1.54 in the control group; p=<0.001) Conclusion: The present study shows thata 50.000 IU/week dose of vitamin D supplementation for 3 months was enough to increase vitamin D levels beyond sufficient and decrease depression symptoms in Saudi Arabian Adults. …"
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Climatic change impacts on the energy requirements for the built environment sector حسب Furqan Tahir (14429547)

"…This will help emphasize increasing energy capacity, improving efficiency, and developing energy policies to reduce and adapt to the climate change implications. …"

Clinical relevance of aortic stiffness in end-stage renal disease and diabetes : implication for hypertension management حسب Bahous, Sola Aoun

"…Aortic stiffness represents a marker of structural but also functional arterial damage associated with increased pressure pulsatility. Carotid–femoral pulse wave velocity (cf-PWV), as a marker of aortic stiffness, may provide a readily available information for the effectiveness of risk reduction strategies. …"
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Peripherally injected cholecystokinin-induced neuronal activation is modified by dietary composition in mice حسب Zeeni, N.

"…In addition, a significant interaction was found between CCK administration and the HF diet, shown by an increased activation in the PVN, which suggests a decrease the inhibiting action of CCK. …"
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Short Report. An innovative training programme for families of children and adolescents with Autism Spectrum Disorder in Qatar: Parents as interventionists حسب Manal Osman Abouelseoud (17346868)

"…<h3>Introduction</h3><p dir="ltr">Previous research has established the association of maladaptive behaviours exhibited by individuals with Autism Spectrum Disorder (ASD) with an increase in the extent of care burden among their caregivers. …"