Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy by Samson Mathews Samuel (18808246)

“…Treatment with a combination of 2DG (5 mM) and metformin (2 mM) also significantly decreased cell proliferation, migration and tubulogenic capacity when compared to cells that were treated with either 2DG or metformin alone. …”

Optimizing pain management and pupil dilation in cataract surgery: a systematic review and meta-analysis of phenylephrine/ketorolac (OMIDRIA®) by Mohamed Abo Zeid (20020680)

“…Data were synthesized using meta-analysis with fixed and random-effects models, and heterogeneity was assessed using the I² statistic.…”

Comparative cost assessment of sustainable energy carriers produced from natural gas accounting for boil-off gas and social cost of carbon by Mohammed Al-Breiki (14152476)

“…<p dir="ltr">As a result of particular locations of large-scale energy producers and increases in energy demand, transporting energy has become one of the key challenges of energy supply. …”

Advanced Thermal Management in Intermittent Electronics: Integrating Metal Foam and Phase Change Materials by Ahmad, Muhammad

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Pushing an existing villa in Dubai to nearly Zero Energy Building passing through AL SA’AFAT rating system by Al Ali, Meera Hamid Obaid

“…Our surrounding environment is effected significantly due to the buildings impact which is a result of excessive energy consumption. …”
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Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways by Daaboul, Hamid E.

“…HC treatment also had antitumor effect in vivo with no significant toxicity to laboratory mice.…”
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Numerical analysis of MHD combined convection for enhanced CPU cooling in NEPCM-filled a trapezoidal cavity by Ahmed M. Hassan (8893106)

“…Le strongly influences mass transfer, with <i>Sh</i>_<em>av</em> increasing by 284.6 % as Le increases. The NEPCM fusion temperature exhibits a non-monotonic effect on <i>Nu</i>_<em>av</em> , with an optimal value at <i>θ</i>_f = 0.5. …”

Functional Connectivity Analysis under Vigilance Decrement and Enhanced Mental States by Hassanin, Omnia

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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy by Jia-Zhen Wu (6844793)

“…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). Concomitantly, we detected increased levels of LAMP-1 (a marker of lysosomal homeostasis) and LAMP-2A (a key marker of CMA). …”

Examining depression, antidepressants use, and class and their potential associations with osteoporosis and fractures in adult women: Results from ten NHANES cohorts by Humam Emad Rajha (22225114)

“…<h3>Introduction</h3><p dir="ltr">Osteoporosis, a significant public health concern, affects millions of adult women globally, leading to increased morbidity and fracture risk. …”

Immune Checkpoints in Circulating and Tumor-Infiltrating CD4+ T Cell Subsets in Colorectal Cancer Patients by Salman M. Toor (8854751)

“…These results highlight the significance of Tregs in the CRC TME and suggest that Tregs may hamper response to IC blockade in CRC patients, but effects of different IC inhibition regimes on Treg levels or activity warrants further investigations. …”

BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells by Ali Alhoshani (3720718)

“…This effect was associated with a significant increase in the percentage of apoptotic MDA-MB-231 cells and in the expression of the apoptotic genes, caspase 3, caspase 7, and BAX, with inhibition of antiapoptotic gene, BCL-2 levels. …”

Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: a systematic review by Maged S. Alhammadi (14150757)

“…Regarding the vertical jaw relation, one study reported a significant decrease in mandibular plane inclination in OC and a significant increase in OOS. …”

Synthesis and analysis of silver–copper alloy nanoparticles of different ratios manifest anticancer activity in breast cancer cells by Sara Al Tamimi (9692615)

“…However, AgCu-NP were significantly toxic to MCF-7 cells at 10 µg/ml concentration, while as AgCu-NP have no toxic effect on healthy cells. …”

The Interactions of Business Environment, Generic Strategy, Operations Strategy, and Business Performance in the Lebanese Industries by Ghazal, Ziad

“…The results confirmed the significance of the direct effects at the aggregate level. …”
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Impact of Using Recycled Materials in the Construction Industry of the United Arab Emirates by Al Zarouni, Tariq

“…Additionally, project participants such as project managers and contractors should increase their awareness on the environmental impacts of C&D waste and incorporate effective waste minimization, recovery, and recycling strategies.…”
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Macroeconomic Conditions and Soundness of UAE Banking Sector by Ali, Dhuha Musleh Fadhel

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Local Over-Expression of VEGF-DDNDC in the Uterine Arteries of Pregnant Sheep Results in Long-Term Changes in Uterine Artery Contractility and Angiogenesis by Abi Nader, Khalil

“…There was a tendency to higher UABF in Ad.VEGF-DΔNΔC compared to Ad.LacZ transduced UtAs (50.58% v/s 26.94%, p = 0.152). There was no significant effect on maternal haemodynamics. An increased number of proliferating endothelial cells and adventitial blood vessels were observed in immunohistochemistry. …”
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The microbiome-lymphoma Axis: A systematic review and Meta-analysis of gut Dysbiosis pattern in diffuse large B-cell lymphoma by Sarah A. Elkourashy (21632903)

“…<h3>Background</h3><p dir="ltr">Gut microbiota has emerged as a critical mediator of immune homeostasis and cancer biology. Increasing evidence suggests that gut dysbiosis may play a significant role in the pathogenesis of diffuse large B-cell lymphoma (DLBCL), the most common and aggressive subtype of non-Hodgkin lymphoma (NHL). …”

A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle by Sanjay Kumar (8853)

“…To identify the most promising bioactive flavonoids against the SARS-CoV-2, this article screened a virtual library of 46 bioactive flavonoids against three promising targets in the SARS-CoV-2 life cycle: human TMPRSS2 protein, 3CLpro, and PLpro. By examining the effects of glycosylation and other structural-activity relationships, the presence of sugar moiety in flavonoids significantly reduces its binding energy. …”