Aryl Hydrocarbon Receptor Promotes Cell Growth, Stemness Like Characteristics, and Metastasis in Human Ovarian Cancer via Activation of PI3K/Akt, β-Catenin, and Epithelial to Mesen... حسب Lubna Therachiyil (4246156)

"…Our results showed that activation of AhR by TCDD in A2780 cells induced the PI3K/AKT pathway followed by induction of anti-apoptotic proteins BCL-2, BCL-xl, and MCL-1. In addition, a significant increase in stemness marker aldehyde dehydrogenase (ALDH1) was observed. …"

Microalgal-based desalination brine remediation: Achievements, challenges, and future research trends حسب Isra E. Gilani (17019066)

"…<p dir="ltr">Desalination brine discharge has several negative impacts on the marine environment, such as increase in salinity levels, effects on marine biodiversity, and alteration of the physical and chemical characteristics of water. …"

Eight Weeks of Plyometric Training Improves Ability to Change Direction and Dynamic Postural Control in Female Basketball Players حسب Yosser Cherni (18174172)

"…However, it did not yield significant inter-group differences in postural control in the antero-posterior plane. …"

Disrupted harvests: how Ukraine – Russia war influences global food systems – a systematic review حسب Hamid El Bilali (15864930)

"…Effects on food utilization are mainly seen in the decrease in diet quality and dietary diversity. …"

Photovoltaic Facades: Key to the Concept of Zero Energy Buildings حسب KAMPADAM, MATHEW GEORGE

"…To sustain our future generations from the adverse effects of greenhouse gases, buildings hold a major potential. …"
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Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese حسب Abdelkrim Khadir (437074)

"…Indeed, HSP60 expression levels in SAT were significantly increased by exercise in the diabetes group, whereas they were decreased in the non-diabetes group. …"

PermGuard: A Scalable Framework for Android Malware Detection Using Permission-to-Exploitation Mapping حسب Arvind Prasad (19997799)

"…The increasing reliance on mobile devices significantly raises the risk of malware attacks, especially for non-technical users who often grant permissions without thorough evaluation, leading to potentially devastating effects. …"

Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults حسب Khaddaj, Rashel

"…Furthermore, the change between both groups was significantly different (-7.61 ±4.03 in the Vitamin D group, -3.50±1.54 in the control group; p=<0.001) Conclusion: The present study shows thata 50.000 IU/week dose of vitamin D supplementation for 3 months was enough to increase vitamin D levels beyond sufficient and decrease depression symptoms in Saudi Arabian Adults. …"
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Chemical characterization and cytotoxic activity evaluation of Lebanese propolis حسب Faour, Wissam H.

"…Interestingly, the decrease in cell viability was accompanied by a significant increase in p53 protein expression levels and PARP cleavage. …"
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A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells حسب Abou-Ghazal, Mohamed K.

"…Although WP1066 did not induce immunological memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (TGF-β, RANTES, MCP-1, VEGF), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …"
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A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce... حسب Abou-Ghazal, Mohamed

"…Although WP1066 did not induce immunologic memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (transforming growth factor-β, RANTES, MCP-1, vascular endothelial growth factor), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …"
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A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells حسب Abou-Ghazal, Mohamed K.

"…We found that the mean percentage of peripheral blood mononuclear cells expressing phosphorylated STAT3 (p-STAT3) was significantly elevated in samples from patients with melanoma brain metastases compared to healthy donors, 16.13 ± 2.48% versus 4.17 ± 1.79%. …"
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Silver-based dressings for the prevention of surgical site infections: evidence from randomized trials حسب S. Younes (22254238)

"…<h3>Background</h3><p dir="ltr"><u>Surgical site infections</u> (SSIs) are a major cause of <u>postoperative complications</u>, increasing morbidity and healthcare costs. Silver-based dressings are commonly used due to their <u>antimicrobial properties</u>, but their effectiveness in reducing SSIs remains unclear. …"

Ethnic-specific association of amylase gene copy number with adiposity traits in a large Middle Eastern biobank حسب Niccolo’ Rossi (14152692)

"…Indeed, lower AMY1 CN was associated with increased total and trunk fat percentages in Arabs (P < 4.60 × 10−3) but not in Persians. …"

Prevalence and global trends of polypharmacy in patients with chronic kidney disease: A systematic review and meta-analysis حسب Lina Naseralallah (14146465)

"…The exact interventions that are likely to significantly mitigate its effect remain uncertain and will need exploration by future prospective and systematic studies.…"

Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs) and Ultrasound. حسب Ibrahim, Mihad

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Metabolic Profiling of Exercise-induced Autophagy-dependent Metabolites in Mouse Plasma حسب Fadel, Joanna

"…Our results show that exercise induced distinct metabolic changes in mouse plasma, with several metabolites, including pregeijerene, androsterone glucuronide, meproscillarin, and N-acetyl methionine, showing significant increases in the exercise group. These changes were largely attenuated by CQ treatment, suggesting their dependence on autophagy. …"
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Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches حسب ALHAJERI, RASHED ABDULLA

"…Higher relative humidity, drier desert climates, larger dust particles/concentration, and lower PV panel tilt angle are all examples of how soiling or its effects are increased. The losses resulting from this can lead to significant losses, especially in a place like Dubai, UAE which meet many of these factors. …"
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Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59 حسب Ramada R. Khaswaneh (22224544)

"…Preserving the level of Factor H and CD59 in MSCs has significant clinical implication to increase their retention rate in hypoxic conditions and prolong their survival.…"

Feasibility of a group-based laughter yoga therapy on anxiety and happiness among community-dwelling older adults: A quasi-experimental study حسب Mona Metwally El-Sayed (17725127)

"…As well as an increase in happiness level among the study group compared to the control group were found (pre = 54.23 (6.60), immediate = 62.05 (4.09), post three-month = 61.95 (4.38), with statistical significant= <0.001 and effect size = 0.677.…"