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301
The promise of tirzepatide: A narrative review of metabolic benefits
Published 2025“…<p>Obesity and type 2 diabetes mellites (T2DM) are intertwined epidemics that continue to pose significant challenges to global public health. We aim to review the available evidence on the metabolic effects of tirzepatide, focusing on weight loss and maintenance of lost weight, body composition alterations, appetite regulation, glycemic control, and lipid profile modulation. …”
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302
Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
Published 2022“…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …”
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303
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
Published 2024“…We also found that BTZ exerted its antitumor effects by generating reactive oxygen species (ROS), as blocking ROS production significantly reduced BTZ-induced apoptotic cell death. …”
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304
Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies
Published 2023“…The non-linear models yielded more significant findings, while the linear models did not indicate any significant effects of exchange rate volatility on trade flows. …”
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305
Application of Cyanobacteria (Roholtiella sp.) Liquid Extract for the Alleviation of Salt Stress in Bell Pepper (Capsicum annuum L.) Plants Grown in a Soilless System
Published 2021“…Moreover, chlorophyll a and b increased significantly compared with seedlings sprayed with water. …”
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306
Joint energy-distortion aware algorithms for cooperative video streaming over LTE networks
Published 2013“…In the proposed approach, mobiles are grouped into collaborative clusters using a low-complexity clustering algorithm. …”
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307
Phosphate-solubilizing bacteria-mediated rock phosphate utilization with poultry manure enhances soil nutrient dynamics and maize growth in semi-arid soil
Published 2025“…Similarly, nutrient uptake improved, with N uptake increasing by 142%, P by 283%, and K by 149.6%. This treatment also increased soil EC and SOM by 43% and 77%, respectively, while soil pH decreased by 3.23%. …”
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308
Regulation of circulating CTRP-2/CTRP-9 and GDF-8/GDF-15 by intralipids and insulin in healthy control and polycystic ovary syndrome women following chronic exercise training
Published 2022“…Intralipids alone had no effects on CTRP-9, GDF-8, or GDF-15. Insulin increased the levels of GDF-15 in control subjects (P = 0.05) during the saline study and in PCOS subjects (P = 0.04) during the intralipid infusion. …”
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309
<i>Haematococcus pluvialis</i> Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells
Published 2022“…Interestingly, apoptosis was mediated by a significant loss of mutant p53 protein, and increased Bax/Bcl2 ratio. …”
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310
A comprehensive review on the use of natural fibers in cement/geopolymer concrete: A step towards sustainability
Published 2023“…In recent years, the usage of fibers has tremendously increased to make significantly robust structures. …”
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311
Arsenic: A double-edged sword
Published 2014“…Long-term exposure significantly increases the risk of heart disease, diabetes, and makes numerous different cell types turn cancerous. …”
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312
Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer
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313
Estimation of power grid topology parameters through pilot signals
Published 2016“…The distribution grid has been the source of an increased amount of electricity production in recent years. …”
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conferenceObject -
314
Competition, regulation, and systemic risk in dual banking systems
Published 2024“…Interestingly, this effect is not significantly different between IBs and CBs. …”
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315
Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Published 2019“…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). Concomitantly, we detected increased levels of LAMP-1 (a marker of lysosomal homeostasis) and LAMP-2A (a key marker of CMA). …”
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316
Exploring the Relationship Between Transformational Leadership Style and Teacher Retention in a Private School in Sharjah
Published 2024“…Analyses revealed that transformational leadership practices, particularly effective communication, decision-making transparency, and motivational strategies, significantly correlate with higher teacher retention. …”
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317
Climate change dynamics for global energy security and equity: Evidence from policy stringency drivers
Published 2024“…The findings reveal that increased financial integration significantly enhances ES by easing capital flow into energy infrastructure, which is crucial for stable energy supply chains. …”
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318
Upgrading co-pyrolysis products from ternary biomass: An investigative study of commercial and locally-made catalysts
Published 2024“…Additionally, catalysts significantly alter the composition of bio-oil, with calcium-based catalysts reducing acid content and increasing aromatics, while zeolites exhibit contrasting trends at different temperatures. …”
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319
Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy
Published 2023Get full text
doctoralThesis -
320
Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling
Published 2018“…HFD also significantly increased the number of adipocytes in the bone marrow microenvironment of WT mice as compared to KO mice. …”