Image 8_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff by Tien Le (634791)

“…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…”

Supplementary Material for: Serum Autotaxin Level Positively Associates with Metabolic Associated Fatty Liver Disease and Hyperuricemia in Postmenopausal Women by Zhang J. (2986470)

“…MAFLD patients showed significant metabolic disturbance presented with increased BMI, blood pressure (P＜0.001) and decreased HDL-C (P＜0.05), as well as liver injury companied by elevated ALT (P＜0.05). …”

Data Sheet 1_Effect of Helicobacter pylori eradication on gastric cancer risk in patients with intestinal metaplasia or dysplasia: a meta-analysis of randomized controlled trials.d... by Qiang Fu (129583)

“…Further, if the study conducted in countries other than those in Asia, sample size <500, percentage of male <50.0%, follow-up duration <5.0 years, and low study quality, then there was no significant association between H. pylori eradication and a decreased risk of gastric cancer.…”

Data_Sheet_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.docx by Junjie Jiang (7255706)

“…</p>Results<p>Analysis of data from the 2007–2018 NHANES survey revealed a significant negative association between CDAI and sleep disorders (OR = 0.854, 95% CI 0.821–0.888, P < 0.001). …”

Data Sheet 1_The Emotional Recession: global declines in emotional intelligence and its impact on organizational retention, burnout, and workforce resilience.pdf by Joshua M. Freedman (22604039)

“…</p>Results<p>Global EQ scores declined by 5.79% (Cohen’s d = 0.22, 95% CI [0.17, 0.27]), with statistically significant decreases across all eight competencies (p < 0.001). …”

Image 2_Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus.pdf by Guanfei Zhao (3815596)

“…</p>Results<p>Patients with SLE exhibited significantly decreased MMP-Low in some peripheral lymphocyte subsets. …”

Data_Sheet_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.docx by Junjie Jiang (7255706)

“…</p>Results<p>Analysis of data from the 2011–2018 NHANES survey revealed a significant negative association between CDAI and sleep disorders (OR = 0.854, 95% CI 0.821–0.888, P < 0.001). …”

DataSheet1_Inversion and analysis of transparency changes in the eastern coastal waters of China from 2003 to 2023 by an improved QAA-based method.docx by Shuhui Cao (10338737)

“…As for the long-term changes, the number of pixels with significantly increased Zsd and those with significantly decreased Zsd and no significant changes accounted for 20.84%, 1.14%, and 78.02%, respectively. …”

Table 2_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.xlsx by Yiwen Li (354034)

“…</p>Results<p>GXN treatment significantly reduced myocardial injury in diabetic mice and decreased oral F. nucleatum abundance, although its effects on other gut microbiota taxa were variable. …”

Subcellular localization and protein level of APC in wild type and <i>Cep290</i> KO cells. by Kazuhiko Matsuo (2880248)

“…Note that fluorescence intensity of APC at the leading edge was significantly decreased in <i>Cep290</i> KO cells. (C) Protein expression levels in wild type and <i>Cep290</i> KO cells were assessed by Western blotting. …”

CircFNDC3B inhibits vascular smooth muscle cells proliferation in abdominal aortic aneurysms by targeting the miR-1270/PDCD10 axis by Baoping Deng (9081380)

“…</i> Our findings revealed a significant upregulation of circFNDC3B expression in AAA clinical specimens compared to normal tissues. …”

Table 1_Eculizumab for the acute attack of neuromyelitis optica spectrum disorder.docx by Qingqing Zhuang (22109089)

“…Following eculizumab, six of the seven ON patients showed significant improvements in visual acuity and visual fields, with five recovering to near-normal or pre-attack vision. …”

Data Sheet 1_Role of intercellular interactions on single cell and population level responses: considerations for multicellular bioreporter design.docx by Douglas Lin (10309772)

“…</p>Results<p>Simulations for 20 s of simulated time show that while final reporter protein count per cell decreased as cell count increased, aggregate final reporter protein number across all cells significantly increased. …”

Table 7_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.xlsx by Yanyao Lu (22163632)

“…The results revealed that S-PPO, S-POD, and S-CAT decreased with prolonged drainage time, whereas the soil redox potential (Eh-mV) and POD increased. …”

Image 3_The role of PCBP1 in carbon ion-induced ferroptosis and inhibition of lung adenocarcinoma proliferation.tif by Zhenchao Kang (20523974)

“…</p>Results<p>Carbon ions significantly inhibited the proliferation of A549 cells, and 5.16 Gy carbon ions significantly induced the expression of differentially expressed genes in these cells. …”

Data Sheet 1_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.docx by Songqin Chen (9625886)

“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”

Image 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Neural lamella remodeling is needed for macrophage invasion. by Bente Winkler (20760273)

“…(<b>C</b>) Panglial expression of <i>Pvf2</i> and concomitant knockdown of <i>STAT92E</i> decreases the number of invaded macrophages by ~ 10-fold. …”

Analysis diagram of economic carrying system. by Hui Li (32376)

“…Our results indicate significant changes in land types within the TGRR from 1986 to 2020, with decreases in arable land, forest land, and grassland, while water bodies, building land, and unused land increased. …”

Analysis diagram of population carrying system. by Hui Li (32376)

“…Our results indicate significant changes in land types within the TGRR from 1986 to 2020, with decreases in arable land, forest land, and grassland, while water bodies, building land, and unused land increased. …”