Image 1_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.tif حسب Songqin Chen (9625886)

"…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…"

Supplementary Material for: The value of diffusion kurtosis imaging to assess liver and kidney recovery after mesenchymal stem cell intervention in CCl4-induced cirrhotic rats حسب Qin J. (5120975)

"…Results: Compared to baseline, there was a significant increase in liver fibers and kidney HE scores by week 12. …"

Table 4_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.xlsx حسب Yanyao Lu (22163632)

"…The results revealed that S-PPO, S-POD, and S-CAT decreased with prolonged drainage time, whereas the soil redox potential (Eh-mV) and POD increased. …"

Data Sheet 1_Association of advanced lung cancer inflammation index with all-cause and cardiovascular mortality in US patients with asthma.pdf حسب Jiatao Li (10033795)

"…Background<p>Asthma poses a significant global health challenge, representing a chronic respiratory disorder marked by airway inflammation. …"

Table 1_Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer.xlsx حسب Xiucheng Jiang (18849564)

"…Notably, mitochondrial haplogroup D4 was significantly associated with a decreased risk of developing EC. …"

Data Sheet 1_Multi-compartment immune cell profiling highlights the prognostic relevance of CD127+ CD8+ T cells for patients with high-grade serous ovarian cancer.docx حسب Rebecca Rothe (10292883)

"…In addition, immune cell subsets varied significantly in their differentiation and phenotypic marker expression. …"

Table 4_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.xls حسب Songqin Chen (9625886)

"…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…"

DataSheet2_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.xlsx حسب Yiyi Zuo (19945293)

"…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …"

The atrium and ventricle exhibit different tissue dynamics during morphogenesis. حسب Juliana Sánchez-Posada (20636677)

"…Total endocardial volume decreases after 58 hpf (D), driven by a reduction in endocardial tissue in both the atrium and ventricle (E); 34–36 hpf: <i>n</i> = 9; 48–50 hpf: <i>n</i> = 10; 58–60 hpf: <i>n</i> = 8; 72–74 hpf: <i>n</i> = 10. …"

Image 1_Application and validation of the machine learning-based multimodal radiomics model for preoperative prediction of lateral lymph node metastasis in papillary thyroid carcin... حسب Jia-Wei Feng (10754067)

"…Current diagnostic methods show significant limitations, with occult LLNM rates of 41.0%-51.7% requiring secondary surgeries. …"

Data Sheet 1_Visual attention during non-immersive virtual reality balance training in older adults with mild to moderate cognitive impairment: an eye-tracking study.pdf حسب Marcos Maldonado-Díaz (11221102)

"…Clinical tests revealed a slight increase, though results were not statistically significant in balance and walking speed (p = 0.063). …"

Table_4_Functional Characterization of Olfactory Proteins Involved in Chemoreception of Galeruca daurica.docx حسب Ling Li (38566)

"…The EAG response of G. daurica females to 2-hexenal was significantly decreased in dsRNA-OBP15-injected treatment compared to the control, and the dsRNA-CSP5-treated females significantly reduced EAG response to eight tested host volatiles (1,3-dithiane, 2-hexenal, methyl benzoate, dimethyl trisulfide, myrcene, hexanal, 1,3,5-cycloheptatriene, and p-xylene). …"

Video 2_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4 حسب Adam Eckardt (20573576)

"…Bet1L knockdown decreased motor neuron size in the lumbar spinal cord, which innervated the siRNA-injected hindlimb. …"

Table 2_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx حسب Jian-Tong (21583487)

"…Correlational analysis revealed significant associations between these pathways and inflammatory/oxidative markers. …"

Image1_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif حسب Chao Bai (4428472)

"…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …"

Table 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx حسب Lili Zhou (265076)

"…</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …"

Evaluating the effectiveness of safety countermeasures at highway–railway grade crossing based on a machine learning framework حسب Mohammadali Zayandehroodi (19746176)

"…Then, the DCLA method achieved 4 distinct clusters optimized by high similarity within each cluster and significant independence among clusters. The effectiveness of countermeasures was computed in terms of CMF and SE. …"

Soil plant available silicon from a bamboo forest on karst mountain in southwest China differs between wet and dry seasons حسب Bin Xu (10691)

"…The soil water-soluble Si and organic matter showed no significant difference between wet and dry seasons. …"

Analysis diagram of Ecological carrying system. حسب Hui Li (32376)

"…Our results indicate significant changes in land types within the TGRR from 1986 to 2020, with decreases in arable land, forest land, and grassland, while water bodies, building land, and unused land increased. …"

Table 1_Altered brain functional network connectivity and topology in type 2 diabetes mellitus.doc حسب Weiwei Ni (9269921)

"…</p>Discussion<p>This study demonstrated significant abnormalities in connectivity and topology of large-scale brain functional networks in T2DM patients. …"