Image 1_A natural PCID2-Targeting compound suppresses hepatocellular carcinoma progression: evidence from structure-based discovery and biological evaluation.png by Zebanuer Yuemaierjiang (22702064)

“…Mechanistically, β-PGG decreased PCID2 expression and downregulated Cyclin D1 and CDK6. …”

Image_3_Angiotensin-I-converting enzyme inhibitory peptides from eel (Anguilla japonica) bone collagen: preparation, identification, molecular docking, and protective function on H... by Huan Xiang (460100)

“…Treatment with GPPGPPGL significantly increased nitric oxide secretion (p < 0.01) and decreased endothelin-1 (ET-1) production in HUVECs.…”

Image 2_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno... by Shao-jun Xu (11633956)

“…Accordingly, we developed the SNS staging and found that the OS and DFS were significantly different among patients at different stages (all P < 0.001). …”

Image 2_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png by Feifei Yang (334047)

“…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …”

Table1_The association of physical activity with kidney function risk among adults with long working hours.docx by Tenglong Yan (14132220)

“…Introduction<p>Long working hours are likely associated with the decreased of kidney function, while physical activity (PA) was linked to improvements in kidney function. …”

Image 3_Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7... by Chunmei Ren (10921089)

“…</p>Results<p>Metformin significantly reduced periapical bone destruction on postoperative days 21 and 28, and decreased the number of osteoclasts on the periapical alveolar bone on postoperative day 28. …”

Table 3_The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review.docx by Thiago Henrique Teodoro (20703731)

“…</p>Conclusion<p>Chronic exercise decreases serum TNF-α and IL-6 levels, lowers the CD4/CD8 ratio, and increases IL-10 after 24 weeks, aiding Th1 and Th2 balance. …”

Table1_Causal association between inflammatory bowel disease and acute pancreatitis: a two-sample bidirectional mendelian randomization study.XLSX by Cong Zhang (582922)

“…Interestingly, AP was suggestively associated with a decreased risk of CD (OR = 0.797, 95% CI = 0.637-0.997, p = 0.047). …”

Flexible Microfluidic Devices for Tunable Formation of Double Emulsion by Uditha Roshan (20841937)

“…This innovative approach significantly advances the field of droplet-based microfluidics, providing on-site, real-time tunability for the generation of double-emulsion droplets with high precision and reproducibility.…”

CLIC1 accelerates oxidative stress in oxygen and glucose deprivation/reoxygenation (OGD/R)-treated HT22 cells by inhibiting the Nrf2/HO-1 signalling pathway. by Jingtong Xiong (22272139)

“…(d) CCK-8 OD values were decreased after Nrf2/HO-1 inhibition, with lower values observed in the OGD/R+CLIC1 silencing+Nrf2/HO-1 inhibition group than the OGD/R+CLIC1 silencing group. …”

Table 1_High-concentrate diet supplemented with hydrolysable tannin improves the slaughter performance, intestinal antioxidant ability and barrier function of fattening lambs.docx by Jian Ma (170138)

“…Also, tannin supplementation significantly increased (p < 0.05) the level of jejunal and ileal total antioxidant capacity and reduced (p < 0.05) the jejunal malondialdehyde concentration in lambs. …”

Data Sheet 1_Identification of potential miRNA biomarkers for neurobrucellosis diagnosis.pdf by Meiling Liu (390553)

“…Among these, four common miRNAs (miR-342-3p, miR-576-5p, miR-15b-5p and miR-499a-5p) were significantly elevated in the infection group compared to controls in both the in-house and validation cohorts. …”

Supplementary file 1_SRC is a potential target of Arctigenin in treating triple-negative breast cancer: based on machine learning algorithms, molecular modeling and in Vitro test.d... by Yuezhou Huang (9998177)

“…Western blotting indicated that AG significantly reduced the levels of Bcl-2, caspase-3, and caspase-9, as well as decreased SRC, p-PI3K-p85, p-AKT1, p-MEK1/2, and p-ERK1/2 expression in TNBC cells in a concentration dependent manner.…”

DataSheet1_Causal association between inflammatory bowel disease and acute pancreatitis: a two-sample bidirectional mendelian randomization study.PDF by Cong Zhang (582922)

“…Interestingly, AP was suggestively associated with a decreased risk of CD (OR = 0.797, 95% CI = 0.637-0.997, p = 0.047). …”

Protocol for our RNA-seq. by Sabih Rashid (5618807)

“…Top graphs depict genes increased in <i>daf-2; aak(0)</i> mutants compared to <i>daf-2</i> controls, while bottom graphs depict those genes that were decreased. Size of bubbles indicate number of genes in their respective categories that were enriched in the dataset. …”

Table4_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg by Yun Zhou (308977)

“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”

Table 2_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.doc by Feifei Yang (334047)

“…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …”

Image 4_Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7... by Chunmei Ren (10921089)

“…</p>Results<p>Metformin significantly reduced periapical bone destruction on postoperative days 21 and 28, and decreased the number of osteoclasts on the periapical alveolar bone on postoperative day 28. …”

Table 1_Global, regional, and national burden of myocarditis and its attributable risk factors in 204 countries and territories from 1990 to 2021: updated systematic analysis.docx by Jiajia Ren (11151738)

“…Concurrently, the age-standardized prevalence rate (ASPR) per 100,000 people also saw a slight increase (no statistical significance) from 6.35 (5.37 to 7.36) to 6.41 (5.48 to 7.44). …”

Data Sheet 1_Evaluation of the epidemiological and economic impact of the ADLIFE intervention on medium- to long-term in patients with advanced chronic disease.pdf by Igor Larrañaga (5434382)

“…Emergency visits and consultations with primary care professionals decreased significantly, while specialist consultations increased. …”