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81
p53 Inhibition in Pancreatic Progenitors Enhances the Differentiation of Human Pluripotent Stem Cells into Pancreatic β-Cells
Published 2023“…Inhibition of p53 using pifithrin-μ (PFT-μ) at the MPC stage resulted in a significant increase in the number of PDX1+/NKX6.1+ cells and a reduction in the number of CHGA+/NKX6.1− cells. …”
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82
Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases
Published 1983“…Following treatment of the hyperthyroidism, control was improved in 63%, with an 11-83% (mean 44%) decrease in insulin dosage in 59% of them. …”
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83
Khalasa date palm leaf fiber as a potential reinforcement for polymeric composite materials
Published 2021“…CE proposes a paradigm shift from a linear economy to a circular economy with the principles of 3Rs: reduce, reuse, and recycle. …”
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84
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85
The Impact of Different Urban Configurations on Outdoor Thermal Comfort: A Case Study of the Military Camps in Abu Dhabi, UAE
Published 2016“…The findings from the three phases of the research showed that selecting the optimal urban configuration decreases air temperature by 2 °C from 33.6 to 31.54 for the base case and the most favourable developed linear from F respectively. …”
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86
Moments-based computation of intermodulation distortion of RF circuits
Published 2001“…However, obtaining the IP3 using traditional harmonic balance simulation requires multitone inputs, which significantly increases the computational costs. On the other hand, analytical approaches based on obtaining closed-form expressions for Volterra functional series are too complex to be fully automated for arbitrary circuit topologies. …”
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87
Analyzing the effectiveness of various coatings to mitigate photovoltaic modules soiling in desert climate
Published 2024“…The results indicate a decrease in light transmittance and an increase in surface coverage area over time due to dust accumulation. …”
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88
Drive‐up INR testing and phone‐based consultations service during COVID‐19 pandemic in a pharmacist‐lead anticoagulation clinic in Qatar: Monitoring, clinical, resource utilization...
Published 2023“…</p> <h3> Results</h3> <p>There was no statistically significant difference between clinic-based and phone-based anticoagulation services in mean time and number of visits within therapeutic range (<i>P</i> = .67; <i>P</i> = .06 respectively); mean number of extreme subtherapeutic and supratherapeutic INR values (<i>P</i> = .32 and <i>P</i> = .34, respectively); incidence of thromboembolic complications and warfarin related hospitalization. …”
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89
Predictors of prolonged hospitalization among geriatric trauma patients using the modified 5-Item Frailty index in a Middle Eastern trauma center: an 11-year retrospective study
Published 2025“…Head injury and bleeding were the leading causes of mortality in the study cohort. There was a significant decrease in the trend of geriatric trauma over the years. …”
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90
Recent advances in the treatment and outcome of locally advanced rectal cancer
Published 1999“…Results There were 219 patients in the early era and 109 in the late era. No significant differences were seen in patients (age, gender, race) or tumor characteristics (mean distance from the anal verge, annularity, fixation). …”
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91
Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
Published 2025“…In direct co-cultures, <i>LDHC</i> knockdown reduced the levels of pro-tumorigenic cytokines (IL-1β, IL-4 and IL-6) and increased the secretion of the chemokine CXCL1. In addition, the number of CD8 + T cells expressing PD-1 and CTLA-4 and the cell surface expression of CTLA-4, TIGIT, TIM3, and VISTA were reduced.…”
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92
Activation of Src kinase in primary colorectal carcinoma An indicator of poor clinical prognosis
Published 2002“…RESULTS By CART analysis, Src activity in tumors elevated more than twofold over normal mucosa was significant. Increased Src activity significantly correlated with Dukes stage, pT and pN classification, and increased u-PAR levels (P < 0.001). …”
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93
Effect of temperature on the rheological properties of neat aqueous Wyoming sodium bentonite dispersions
Published 2017“…The Bingham yield stress, from the low shear rate data, increased linearly with temperature, while the plastic viscosity decreased with temperature, in a manner very similar to the decrease of water viscosity with temperature. …”
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94
Targeting of lactate dehydrogenase C dysregulates the cell cycle and sensitizes breast cancer cells to DNA damage response targeted therapy
Published 2021“…Silencing LDHC in four breast cancer cell lines significantly increased the presence of giant cells, nuclear aberrations, DNA damage, and apoptosis. …”
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95
Dynamic Change in Insulin Resistance Induced by Free Fatty Acids Is Unchanged Though Insulin Sensitivity Improves Following Endurance Exercise in PCOS
Published 2018“…Skewed data were log transformed and expressed as mean ± SEM.</p><h3>Results</h3><p dir="ltr">Before exercise, women with PCOS had a higher HOMA-IR and lower VO2 max than controls. …”
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96
Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase
Published 2022“…The formed melanospheres appear to be enriched with embryonic stem cell marker mRNAs, the expression of which is potentiated by dex. Expression of cancer stem cell markers (CD133, CD44, ganglioside GD2) was significantly increased in A375 spheres, as detected by flow cytometry. …”
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97
PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer
Published 2019“…<div><p>Triple negative breast cancer (TNBC) is the most aggressive type of breast cancer, which shows resistance to common breast cancer therapies, as it lacks the expression of the most common breast cancer targets. …”
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An Analysis of Thermal Comfort at the School Outdoor Spaces: A Case Study of the American School of Creative Science, Dubai, UAE
Published 2022“…Outdoor school spaces are significant spaces which, regardless of a child’s residential area, provide great opportunity for outdoor space exploration leading to overall enhancement to the students’ wellbeing. …”
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99
G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome
Published 2020“…CDH10 overexpression significantly reduces cellular movements in breast cancer cell lines and prevents the hypoxia-mediated increase in cell motility. …”
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100
Effects of ethanol addition to diesel–biodiesel blends on the CI engine characteristics
Published 2024“…All blends show an increase in brake mean effective pressure (BMEP) compared to B0, with the maximum enhancement observed in B10 with an average increase of 13% across all speeds. …”