Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation حسب Mona Elsafadi (18614905)

Malignant peritoneal mesothelioma interactome with 417 novel protein–protein interactions حسب Kalyani B. Karunakaran (12478431)

"…Some genes had tissue-specific expression in extramedullary hematopoietic sites and the expression of some genes could be correlated with unfavourable prognoses in various cancers. 39 out of 152 drugs that target the proteins in the interactome were identified as potentially repurposable for MPeM, with 29 having evidence from prior clinical trials, animal models or cell lines for effectiveness against peritoneal and pleural mesothelioma and primary peritoneal cancer. …"

Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy حسب Hamed Elgendy (14148846)

Toxicity assessment of di(2-ethylhexyl) phthalate using zebrafish embryos: Cardiotoxic potential حسب Azza Naïja (19137067)

"…Although DEHP showed negligible influence on the length and pericardial area of exposed embryos, it led to multiple bodily deformities. Gene expression analyses of key cardiogenic and inflammatory genes evidenced alterations in tbx20, bcl2, and il1b expression in Zebrafish embryos at 96 h post-fertilization. …"

DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression حسب Mohamed Abu-Farha (25322)

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression حسب Rached, Johnny

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030) حسب Khaled F. Alkaraki (22051967)

"…This study aimed to model past, present, and future LULCC on Land Surface Temperatures in the Greater Amman Municipality (GAM) in Jordan between 1980 and 2030. …"

Transcriptome and Literature Mining Highlight the Differential Expression of ERLIN1 in Immune Cells during Sepsis حسب Susie S. Y. Huang (2824502)

"…Septic stimulation induced a significant increase in ERLIN1 expression; however, ERLIN1 was differentially expressed among the immune blood cell subsets. …"

Sequence conservation and variability of imprinting in the Beckwith–Wiedemann syndrome gene cluster in human and mouse حسب El-Maarri, Osman

"…In human and mouse most imprinted genes are arranged in chromosomal clusters. This linked organization suggests coordinated mechanisms controlling imprinted expression. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Novel Synonymous Variant in<i> IL7R</i> Causes Preferential Expression of the Soluble Isoform حسب Rafah Mackeh (14151225)

"…</p><h3>Conclusion</h3><p dir="ltr">In this study, we identified a novel rare synonymous mutation causing a loss of IL-7Rα expression at the cellular membrane. This case demonstrates the value of reanalyzing genetic data based on the clinical phenotype and highlights the significance of functional studies in determining the pathogenicity of genetic variants.…"

Comprehensive analysis of circulating miRNA expression profiles in insulin resistance and type 2 diabetes in Qatari population حسب Khaoula Errafii (10914446)

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

"…In the TCGA TNBC/Basal-like cohort the <b><i>MAP3K21</i></b><b> </b><b>rs1294255-G</b> allele was associated with a decreased OVS. High expression of <i>CCL5</i> in breast tumors was significantly associated with an increased OVS in all BC patients, but particularly in TNBC/Basal-like patients. …"

Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke حسب Ghulam, Jeelani Pir

"…We aimed to identify distinctive expression patterns of circulating EV-miRNAs in AIS patients. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke حسب Ghulam Jeelani Pir (13914063)

"…Key hub genes within these networks include TP53, BCL2, Akt, CCND1, and NF-κB. …"

Discovery of new genomic regions and candidate genes implicated in the natural variation of barley peduncle length and plant height حسب Zenaba Khatir (22045928)

"…The presence of 23 candidate genes was discovered after predicting candidate genes underlying significant relationships. …"

The Paget's disease of bone risk gene <i>PML</i> is a negative regulator of osteoclast differentiation and bone resorption حسب Sachin Wani (11704868)

"…Genome-wide association studies identified a susceptibility locus for PDB tagged by rs5742915, which is located within the PML gene. Here, we have assessed the candidacy of PML as the predisposing gene for PDB at this locus. …"

Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response حسب Noura Al-Zeheimi (5177066)

"…From a panel of tested proteins and genes, we found that the levels of plasma NRP-1, placenta growth factor (PlGF) and immune cell expression of the transcription factor <i>SNAI1</i> before and after NAC were significantly different. …"

Parkinson’s disease and schizophrenia interactomes contain temporally distinct gene clusters underlying comorbid mechanisms and unique disease processes حسب Kalyani B. Karunakaran (12478431)

"…DGN1 had unique SZ interactome genes highly expressed across developmental stages, corresponding to a neurodevelopmental SZ subtype. …"

Genome-wide differential expression profiling of long non-coding RNAs in FOXA2 knockout iPSC-derived pancreatic cells حسب Ahmed K. Elsayed (13275302)

"…Furthermore, we constructed co-expression networks linking significantly downregulated lncRNAs with differentially expressed pancreatic mRNAs.…"