Postprandial lipaemia 10 and 34 hours after playing football: Does playing frequency affect the response? by Darren J. Paul (6905450)

“…For the 3FOOT, there was a non significant decrease in postprandial TG AUC (-2.7%; p = 0.73; 95%CI = -2.0 to 1.5; ES = 0.05) and iAUC (-17.5%; p = 0.41; 95%ci = -2.5 to 1.1; ES = 0.31) from 10 to 34 hrs, respectively. …”

Optimum sizing of steam turbines for concentrated solar power plants by Poullikkas, Andreas

“…Finally, although the cost of electricity of a CSP plant with capacities greater than 1MWe is significantly reduced to less than 1US$/kWh, currently such technology can only become economically viable through supporting schemes.…”
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ACSS2 Promotes Proliferation and Invasiveness of Skov-3 and PA-1 Ovarian Cancer Cell Lines under Hypoxia by Mroweh, Ola

“…Migration and invasion assays revealed that ACSS2 inhibition significantly reduced cellular motility and invasiveness, particularly in hypoxia. …”
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Neratinib and metformin: A novel therapeutic approach against HER2-Positive Breast Cancer by Kheraldine, Hadeel

“…Results: Our data revealed that this combination therapy significantly reduced cell viability compared to individual treatments and exhibited a synergistic effect in HER2-positive BC cells. …”
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Clinical correlates of white-matter abnormalities on head magnetic resonance imaging by Dimassi, Hani

“…The children with white-matter abnormalities and decreased tone had significantly less signal intensity abnormality than the other study groups. …”
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Photobiomodulation: A Systematic Review of the Oncologic Safety of Low-Level Light Therapy for Aesthetic Skin Rejuvenation by Graeme Ewan Glass (17733711)

“…The same light parameters mainly reduce neoplastic cell proliferation and viability or else make no difference. …”

Unsustainability in emergent systems by Haddad, Marc

“…In this paper we present a detailed case study of the passenger road transport system in the Greater Beirut Area (GBA) where we identify the root causes of the major problems facing the system today and over the long-term. …”
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On the benefits of sleep by Nature Research (16552612)

“…People who work nights are exposed to artificial light, and this significantly affects the expression of “clock genes” that synchronize body functions to the day–night cycle. …”

Anti-angiogenic effect of nano-formulated water soluble kaempferol and combretastatin in an in vivo chick chorioallantoic membrane model and HUVEC cells by Gowtham Kumar Subbaraj (17807615)

“…The solvent evaporation method was used to synthesize the nano-formulated water-soluble kaempferol and combretastatin and characterized using various analyses such as dynamic light scattering (DLS) and Fourier-transform infrared (FT-IR) spectroscopy.The anti-angiogenic activity of native, nano-formulated water-soluble kaempferol and combretastatin was investigated by cell viability on HUVEC and A498 cell lines, while chick chorioallantoic membrane (CAM) assay was utilized to assess morphometric and histopathological changes, and mRNA expressions of VEGF-A and FGF2 using qRT-PCR. MTT assay results revealed that the combination of nano-formulated water-soluble kaempferol and combretastatin significantly reduced the cell viability compared to control, individual treatments of native, nano-formulated water-soluble kaempferol, and combretastatin. …”

RFX3 is essential for the generation of functional human pancreatic islets from stem cells by Bushra Memon (4792767)

“…Despite a significant reduction in the expression levels of pancreatic islet hormones, the pan-endocrine marker chromogranin A remained unchanged at both EP and islet stages, likely due to an increase in the abundance of enterochromaffin cells (ECs). …”

In vivo assessment of the nephrotoxic effects of the synthetic cannabinoid AB-FUBINACA by Ayman Alzu’bi (13162392)

“…These findings were also correlated with increased expression of major apoptosis regulatory markers (Bax, caspase-9, caspase-3) and reduced expression of mitochondrial complexes I, III, and IV.…”

Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity by Mohammed R. Shaker (10316180)

“…Our data reveal that upregulation of <i>KLOTHO</i> significantly reduced β-amyloid-induced neuronal degeneration and apoptosis, as evidenced by decreased cleaved caspase-3 expression and preservation of axonal integrity. …”

Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors by Noura Aldous (15429873)

“…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …”

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

Therapeutic Impact of P-PENT, P-HEX and 5CLSS (IV) Platinum (IV) complexes on Acute Myeloid Leukemia in vitro and in vivo by Bou Chacra, Joelle

“…Initiating animal treatment 4 days post inoculation (early stage) using P-PENT or P-HEX at 5 mg/kg once or twice per week revealed similar engagement of animal survival rate compared to negative control. Both complexes significantly reduced spleen weight and CD11B expression compared to untreated leukemic controls. …”
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Novel platinum II and platinum IV complexes exhibit potent cytotoxicity and selectivity towards several cancer cell lines by Elias, Elias

“…Evaluation of apoptotic proteins’ expression was performed using western blots. Results showed that both complexes significantly reduced cancer cell viability and exhibited 7 to 20-fold higher cytotoxicity compared to cisplatin. …”
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Exploring the Fecal miRNA Profile in FMF Patients and the Role of miR-21-5p in Inflammatory Pathways Associated with FMF Pathogenesis by Chaaban, Ahlam

“…The inhibition of mir-21-5p in LPS-stimulated THP-1 derived macrophages reduced the activation of NF-κB and inflammasome pathways. …”
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Cold responses and hormonal echoes: a comprehensive view of Raynaud’s vascular dysfunction by Manal Fardoun (16328847)

“…Indeed, estrogen plays a fundamental role in potentiating the expression and function of α2C adrenoceptor (α2C-AR), the sole mediator of local cooling-induced vasoconstriction. …”

Hemodynamics of small aneurysm pairs at the internal carotid artery by Jou, Liang-Der

“…The maximum wall shear stress increases for serial aneurysms, but decreases for parallel aneurysms. Interaction between parallel aneurysms is not significant; however, the proximal aneurysm in serial aneurysms may be subject to a greater rupture risk.…”
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Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer by Sampath, Lakshmi

“…Results: (DTPA)n-trastuzumab-(IRDye800)m showed significantly greater binding to SKBr3 cells than to MDA-MB-231 cells. …”
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