Gut Microbiota in Familial Mediterranean Fever: Insights into Microbial Patterns and Disease Severity حسب Rukaya Basala

"…Our findings revealed no significant differences in gut microbiota composition or diversity between FMF patients and healthy controls, nor among FMF subgroups stratified by disease severity. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway حسب Olfa Khalifa (10914452)

"…<p dir="ltr">Non-alcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. …"

Large-scale association analysis identifies new risk loci for coronary artery disease حسب Deloukas, Panos

"…Coronary artery disease (CAD) is the commonest cause of death. Here, we report an association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching genome-wide significance, taking the number of susceptibility loci for CAD to 46, and a further 104 independent variants (r2 < 0.2) strongly associated with CAD at a 5% false discovery rate (FDR). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Trends of the Dementia Burden in South Asia: An Analysis of 2021 Global Burden of Disease Study حسب Shubham Chauhan (21334742)

"…</p><h3>Methods</h3><p dir="ltr">Data from the Global Burden of Disease (GBD) 2021 report were analyzed using descriptive statistics and join point regression analysis. …"

National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050 حسب Marie, Ng

"…MethodsIn this analysis, self-reported and measured anthropometric data were extracted from 134 unique sources, which included all major national surveillance survey data. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Primary mediastinal choriocarcinoma presenting as cutaneous metastasis with resistance to chemotherapy: case report and literature review حسب Khaled A. Murshed (14151927)

"…The patient also had significant weight loss during the last 5 months along with an episode of generalized seizure. …"

Myeloid Cells in Circulation and Tumor Microenvironment of Colorectal Cancer Patients with Early and Advanced Disease Stages حسب Salman M. Toor (8854751)

"…Notably, patients with advanced disease stages showed significantly higher levels of GMCs compared to early stages in whole blood, but PBMCs and tumor-infiltrating myeloid cells did not show any significant differences. …"

Prevalence of iron overload in patients with chronic kidney disease on peritoneal dialysis: A scoping review حسب Abdulqadir J. Nashwan (11659453)

"…<h3>Background and Aims</h3><p dir="ltr">Chronic kidney disease (CKD) patients undergoing peritoneal dialysis (PD) are susceptible to complications, including iron overload, which can significantly impact their prognosis and overall health. …"

When Copper Meets Autoimmunity: A Rare Coexistence of Wilson's Disease and Systemic Lupus Erythematosus حسب Suresh Bhagoowani (22330471)

"…<p dir="ltr">The coexistence of systemic lupus erythematosus (SLE) and Wilson's disease (WD) is exceedingly rare, posing significant diagnostic challenges due to overlapping clinical presentations. …"

Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort حسب Muneerah Smith (12542939)

"…As expected, patients with severe disease showed significantly higher antibody titers and interestingly also had significantly broader epitope coverage. …"

Risk of Serious Infections in Patients Treated With Biologic or Targeted‐synthetic Disease Modifying Antirheumatic Drugs in Qatar حسب Sreethish Sasi (14151873)

"…Because of associated immune dysfunction, opportunistic or serious infections (SIs), and latent disease reactivation is frequently reported. This study aimed to investigate the epidemiology, risk factors, and outcomes of SIs in patients treated with b/tsDMARDs in Qatar.…"

The effect of Dopamine Agonists on patients with advanced Parkinson's disease subjected to subthalamic deep brain stimulation. (c2000) حسب Jabre, Mazen Gerges

"…The management of this disease is symptomatic, mainly based on the use of levodopa. …"
احصل على النص الكامل
احصل على النص الكامل

Photobiomodulation Suppresses Alpha-Synuclein-Induced Toxicity in an AAV-Based Rat Genetic Model of Parkinson’s Disease حسب Abid Oueslati (816135)

"…In the present study, we report that chronic PMB treatment mitigates dopaminergic loss induced by unilateral overexpression of human α-synuclein (α-syn) in the substantia nigra of an AAV-based rat genetic model of Parkinson’s disease (PD). …"

ALOX5AP gene variants show differential association with coronary artery disease in different populations حسب Alwan, Ahmad

"…Coronary artery disease (CAD) is a complex disease with various components, genetic as well as environmental. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease حسب Nour K. Majbour (8809316)

"…<p dir="ltr">Several studies reported an association between CSF alpha-synuclein (α-syn) and tau in Alzheimer’s disease (AD), and demonstrated the significance of α-syn in improving the diagnostic sensitivity/specificity of classical AD CSF biomarkers. …"

Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP) حسب Anas Hamad (9545771)

"…However, the cancer-related burden on patients, healthcare systems, and the economy is expected to expand; thus, cancer remains a significant public healthcare issue in Qatar. Qatar’s free access to cancer care represents a considerable economic burden. …"

Potentially inappropriate home medications among older patients with cardiovascular disease admitted to a cardiology service in USA حسب Sheikh-Taha, Marwan

"…Inclusion criteria were age of 65 years and above, history of cardiovascular disease, and admission to the cardiology service. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Association Between Religiosity, Spirituality, and Medication Adherence Among Patients with Cardiovascular Diseases: A Systematic Review of the Literature حسب Marwa Elhag (14151282)

"…The other four studies reported a negative or null association between R/S and medication adherence. …"

Neonatal autoimmune lymphoproliferative syndrome with a novel pathogenic homozygous FAS variant effectively treated with sirolimus: Case report حسب Fawzia M. Elgharbawy (17045534)

"…(lle259*). Sirolimus significantly reduced DNTs and substantially relieved the patient’s clinical symptoms.…"

Burden of Transport-Related Injuries in the Eastern Mediterranean Region: A Systematic Analysis for the Global Burden of Disease Study 2017 حسب Saeid Safiri (3713035)