يعرض 1,321 - 1,340 نتائج من 1,684 نتيجة بحث عن '(( significantly greatest decrease ) OR ( significantly impair decrease ))', وقت الاستعلام: 0.31s تنقيح النتائج
  1. 1321

    Image 1_Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of Staphylococcus aureus biofilm formation.jpeg حسب Amirmohammad Afsharnia (22569827)

    منشور في 2025
    "…The RNA sequencing analysis of the treated biofilms indicated that, compared to NGAM, GAM leads to a more pronounced downregulation of S. aureus adhesion genes (eno, ebps, and sraP) and genes involved in arginine biosynthesis and tricarboxylic acid (TCA) pathways, which are essential for biofilm proteinaceous structure. The decreased pH in the biofilm environment treated with higher GAM concentrations supports its observed anti-biofilm activity and is likely linked to impaired pH homeostasis resulting from the downregulation of ureABC genes and disruption of urea metabolism, a process interconnected with arginine biosynthesis. …"
  2. 1322

    Supplementary Material for: Impact of the apolipoprotein E ε4 allele on cognition and omega-3 fatty acid levels in the plasma membrane of red blood cells in healthy elderly Japanes... حسب figshare admin karger (2628495)

    منشور في 2025
    "…The ratio of docosahexaenoic acid (DHA) to arachidonic acid was significantly decreased, and the erythrocyte eicosapentaenoic acid (EPA) and DHA levels tended to be reduced in APOE4 carriers. …"
  3. 1323

    Image 7_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"
  4. 1324

    Image 10_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"
  5. 1325

    Image 8_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"
  6. 1326

    The regulation of AsfR on tmRNA expression mediates bacterial motility and virulence حسب Huimin Chang (21142907)

    منشور في 2025
    "…Consistently, the transcription level of tmRNA was significantly decreased in Δ<i>asfR</i> compared with WT of <i>A. veronii </i>by quantitative real-time PCR (RT-qPCR) analyses. …"
  7. 1327

    Table 1_Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of Staphylococcus aureus biofilm formation.xlsx حسب Amirmohammad Afsharnia (22569827)

    منشور في 2025
    "…The RNA sequencing analysis of the treated biofilms indicated that, compared to NGAM, GAM leads to a more pronounced downregulation of S. aureus adhesion genes (eno, ebps, and sraP) and genes involved in arginine biosynthesis and tricarboxylic acid (TCA) pathways, which are essential for biofilm proteinaceous structure. The decreased pH in the biofilm environment treated with higher GAM concentrations supports its observed anti-biofilm activity and is likely linked to impaired pH homeostasis resulting from the downregulation of ureABC genes and disruption of urea metabolism, a process interconnected with arginine biosynthesis. …"
  8. 1328

    Table 1_Mowing of Carex brevicuspis (Cyperaceae) improves food quality for herbivorous geese in Dongting Lake: the potential mechanisms.xlsx حسب Tao Wu (16763)

    منشور في 2025
    "…However, mowing treatments also significantly decreased plant height, density, aboveground biomass, and the biomass of belowground bud banks, which potentially impairs the long-term recovery and sustainability of plant. …"
  9. 1329

    Image 3_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"
  10. 1330

    Image 2_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"
  11. 1331

    Image 9_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"
  12. 1332

    Image 5_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"
  13. 1333

    Image 1_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"
  14. 1334

    Image 4_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg حسب Xiao Chen (260187)

    منشور في 2024
    "…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …"
  15. 1335

    Data Sheet 1_Iron modulates barrier integrity and stem cell function of small intestine during experimental colitis.docx حسب Shubin Wang (3105348)

    منشور في 2025
    "…In addition, STAT3 and ERK pathways in intestinal epithelium were impaired during experimental colitis, and iron content significantly interrupted the expression of p-STAT3 and p-ERK1/2 within small intestine.…"
  16. 1336

    Cows' BHB impacts on calf BAT growth and metabolic health حسب Yanting Chen (20532152)

    منشور في 2025
    "…The results showed that although high BHB levels had no effect on calf birth weight or growth, they significantly impaired glucose sensitivity, increased stress genes and decreased brown adipose tissue mass, thermogenic proteins and mitochondrial density. …"
  17. 1337

    Dupilumab improves sense of smell and clinical outcomes in patients with severe chronic rhinosinusitis with nasal polyps with anosmia حسب Andrew P. Lane (20367704)

    منشور في 2024
    "…<p>Loss of sense of smell is a cardinal symptom of chronic rhinosinusitis with nasal polyps (CRSwNP) and significantly impacts health-related quality-of-life. …"
  18. 1338

    <b>Metabolic Perturbations and Ectopic Fat Deposition in Low Birthweight Subjects</b><b>– Effects of a 4 Week Carbohydrate Overfeeding Challenge</b> حسب Charlotte Brøns (261017)

    منشور في 2025
    "…Subcutaneous adipose tissue (SAT) density was lower in LBW subjects and decreased during COF in both groups. Serum alanine, phosphatidylcholines, and triglycerides increased significantly more in LBW subjects during COF. …"
  19. 1339

    Prolonged sitting time and all-cause mortality: the mediating and predictive role of kidney function markers حسب Li Wang (15202)

    منشور في 2025
    "…</p> <p>Prolonged daily sitting time is significantly associated with an increased risk of all-cause mortality, potentially mediated by impaired kidney function. …"
  20. 1340

    The regulation of AsfR on tmRNA expression mediates bacterial motility and virulence in <i>aeromonas veronii</i> حسب Huimin Chang (12537320)

    منشور في 2025
    "…Consistently, the transcription level of tmRNA was significantly decreased in Δ<i>asfR</i> compared with WT of <i>A. veronii</i> by quantitative real-time PCR (RT-qPCR) analyses. …"