Burden of injuries caused by fire, heat, and substances in Incidence, Prevalence and Death between 1990 and 2021. by Shi Huang (125861)

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Decomposition analysis of gastric cancer burden in Taiwan, stratified by gender. (A) Incidence. (B) Prevalence. (C) Mortality. (D) DALYs. Positive values on the X-axis indicate an... by Xiaohuang Yang (10182727)

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Distribution of continuous variables of all 3 visits of group 1 (placebo) and group 2 (placebo) that have no significant difference among the groups. by Nattapon Riengvirodkij (11268720)

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The result of molecular dynamics simulation. by Ashraf Attia Mahmoud (21262201)

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Extraction of demaging missense mutations from the TCGA Database. by Ashraf Attia Mahmoud (21262201)

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Structural alterations in hydrogen bond networks of the TP53 protein caused by mutations G266E (A-B), G105C (C-D), R273C (E-F), R280G (G-H), and Q136P (I-J). by Ashraf Attia Mahmoud (21262201)

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(A) The distribution of mutations within the 3D structure of the TP53 protein. by Ashraf Attia Mahmoud (21262201)

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The result of the secondary structure prediction of native and six mutant proteins of TP35 protein using the SOPMA server. by Ashraf Attia Mahmoud (21262201)

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Graph illustrating the distribution of mutations across 20 genes. by Ashraf Attia Mahmoud (21262201)

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Molecular dynamics simulation results for Apo-TP53 (red), wild-typeTP53. by Ashraf Attia Mahmoud (21262201)

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Effect of mutations on protein stability predicted by I-MUTANT 2.0, MUpro and CUPSAT. by Ashraf Attia Mahmoud (21262201)

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P53 mutant docking results (HDOCK and pyDOCK servers). by Ashraf Attia Mahmoud (21262201)

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Oncogenic Classification of TP53 missense mutations. by Ashraf Attia Mahmoud (21262201)

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Computational analysis of missense mutations using PhD-SNP, PANTHER and, SNPs&GO. by Ashraf Attia Mahmoud (21262201)

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Redocking results showing the interaction between the TP53 protein (white ribbon) and its DNA dodecamer ligand (magenta and blue) from PDB ID: 2AC0, highlighting the binding confor... by Ashraf Attia Mahmoud (21262201)

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Result of the phenotypic analysis. by Ashraf Attia Mahmoud (21262201)

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Oncogenic nature of mutations predicted using CScape and CScape-somatic. by Ashraf Attia Mahmoud (21262201)

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(A) Pie chart showing the distribution of mutation types identified within the TP53 gene. by Ashraf Attia Mahmoud (21262201)

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Structural clashes in TP53 mutants: (A) G266E mutation causes steric clashes with PHE109 and LEU257, destabilizing the structure. by Ashraf Attia Mahmoud (21262201)

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(A) TP53 expression levels are elevated in TP53-mutant and nonmutant HNSC samples compared to normal tissues. by Ashraf Attia Mahmoud (21262201)

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