Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson’s disease حسب Nour K. Majbour (8809316)

"…<h3>Background</h3><p dir="ltr">Despite decades of intensive research, to date, there is no accepted diagnosis for Parkinson’s disease (PD) based on biochemical analysis of blood or CSF. …"

Microbial Dysbiosis Tunes the Immune Response Towards Allergic Disease Outcomes حسب Tracy Augustine (14149932)

"…<p>The hygiene hypothesis has been popularized as an explanation for the rapid increase in allergic disease observed over the past 50 years. Subsequent epidemiological studies have described the protective effects that in utero and early life exposures to an environment high in microbial diversity have in conferring protective benefits against the development of allergic diseases. …"

Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases حسب Mazhar Pasha (11197767)

"…Thus, the aim of this review is to discuss the upstream regulators and the downstream effectors of Sestrins and to highlight the significance of Sestrin2 as a biomarker and a therapeutic target in diseases such as metabolic disorders, cardiovascular and neurodegenerative diseases, and cancer.…"

HbA1c over 8.5% is not predictive of increased infection rate following penile prosthesis implant surgery in diabetic patients with erectile dysfunction حسب Raidh Talib (14779198)

"…Penile prosthesis implantation infection rate in a large series of diabetic patients was low with no significant association between haemoglobinA1c level and penile prosthesis implantation infection observed.…"

The effect of vancomycin doses greater than 2 grams on serum creatinine and vancomycin trough levels حسب Mansour, Hanine

"…The use of doses greater than 2 grams of IV vancomycin did not show a statistically significance increase in serum creatinine. The two subjects who did have a significant increase in serum creatinine were receiving concomitant nephrotoxins. …"
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Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation حسب Larissa Haertle (3864310)

"…Furthermore, T21 patients have a high risk of developing Alzheimer’s disease (AD) early in life, characterized by the presence of senile plaques of amyloid protein and neurofibrillary tangles, leading to neuronal loss and cognitive decline. …"

Machine Learning based Model Reveals the Metabolites Involved in Coronary Artery Disease حسب Fathima Lamya (22565261)

"…The results show that 173 metabolites ( P < .05) are significantly associated with CAD. Of these metabolites, the majority (95/173, 54.91%) were high in CAD patients, while 45.09% (78/173) were high in the control group. …"

Prevalence of non-communicable disease and the associated factors among healthcare workers in Qatar حسب Ayman Al-Dahshan (8962568)

"…<h3>Background</h3><p dir="ltr">Non-communicable diseases (NCDs) significantly impact global health and contribute to economic burdens and premature deaths, with healthcare workers (HCWs) being at high risk. …"

Mechanical Efficiency at Different Exercise Intensities Among Adolescent Boys With Different Body Fat Levels حسب Georges Jabbour (754884)

"…Multiple linear regressions showed that body weight (ß = -0.64, p < 0.001), energy consumption (ß = -0.24, p < 0.05) and lipid oxidation (ß = 0.69, p < 0.01) were significant predictors of ME at 50%HRmax. However, at 75%HRmax and V˙O_2peak, significant predictors of ME were epinephrine (ß = 0.34, ß = 0.49, respectively, ps = 0.01), norepinephrine (ß = 0.26, ß = 0.60, respectively, ps < 0.05) and power output (ß = 0.62, ß = 0.71, respectively, ps < 0.01). …"

Lipid profile in Parkinson's disease: The potential role of brain-derived neurotrophic factor حسب Mahmoud A. Alomari (14780446)

"…Subsequent ANCOVA revealed differences (p < 0.05) in TC, HDL, LDL, TC/LDL, and TriG/HDL but not in glucose, TriG, and TC/HDL among the patients with low-BDNF versus high-BDNF.</p><h3>Significance</h3><p dir="ltr">The results demonstrate a relationship of BDNF with lipid profile suggesting the importance of BDNF for lipid metabolism in PD.…"

Anti-amyloid monoclonal antibody therapies in Alzheimer’s disease – a scoping review حسب Shahd Abubaker Elamin (22569539)

"…<p dir="ltr">Alzheimer’s disease (AD) is a progressive neurodegenerative disorder affecting millions worldwide, and with advancements in the medical field, Anti-amyloid monoclonal antibodies (AA mAbs) targeting amyloid-β have emerged as potential disease-modifying agents altering AD pathology. …"

Endocrine contribution to the sexual dysfunction in patients with advanced chronic kidney disease and the role of hyperprolactinemia حسب Haitham Elbardisi (14058048)

"…Patients treated with cabergoline (<i>n</i> = 26) showed a significant increase in LH levels (<i>p</i> = .003) and a significant decrease in prolactin levels (<i>p</i> = .003). …"

Mulberry Leaf Disease Detection Using CNN-Based Smart Android Application حسب Abdus Salam (1918387)

"…However, mulberry trees are highly susceptible to diseases, spreading rapidly and causing significant losses. …"

EEG-Based Semantic Vigilance Level Classification Using Directed Connectivity Patterns and Graph Theory Analysis حسب Yahya, Fares

"…Behaviorally, all subjects demonstrated vigilance decrement as reflected by the significant increase in response time and reduced accuracy. …"
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Can the Salivary Microbiome Predict Cardiovascular Diseases? Lessons Learned From the Qatari Population حسب Selvasankar Murugesan (4376506)

"…This study aims to identify whether a predictive salivary microbiome signature is associated with a high risk of developing CVD in the Qatari population.…"

Whole blood DNA aberrant methylation in pancreatic adenocarcinoma shows association with the course of the disease حسب El Maarri, Osman

"…Additionally, high methylation levels at TNFRSCF10C were associated with positive perineural spread of tumor cells, while higher methylation levels of TNFRSF10C and ACIN1 were significantly associated with shorter survival. …"
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Trends of the Dementia Burden in South Asia: An Analysis of 2021 Global Burden of Disease Study حسب Shubham Chauhan (21334742)

"…While prevalence rates experienced a minor decline, Disability‐Adjusted Life Years (DALYs) rose from 272.02 to 308.27 per 100,000, reflecting an increasing burden of the disease. Notably, Nepal significantly reduced its incidence rates, while Pakistan saw an increase in mortality rates. …"

The role of preoperative transfusion in sickle cell disease, a systematic review and meta-analysis حسب Yasamin Abdu (15899155)

"…Further high-quality studies are needed to refine recommendations.…"

Exploring Ultra-Processed Foods: Impact on Satiety, Eating Patterns, Blood Glucose Levels and Food Addiction حسب Mamo, Tracy G.

"…However, no significant associations were found between UPF intake and emotional eating, overall satiety ratings, psychological distress (PHQ-4), or fasting BG levels (p = 0.171). …"
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Photobiomodulation: A Systematic Review of the Oncologic Safety of Low-Level Light Therapy for Aesthetic Skin Rejuvenation حسب Graeme Ewan Glass (17733711)