Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients by Salman M. Toor (8854751)

“…<p dir="ltr">Increased levels of myeloid cells, especially myeloid-derived suppressor cells (MDSCs), have been reported to correlate with bad prognosis and reduced survival in cancer patients. …”

National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050 by Marie, Ng

“…BackgroundOver the past several decades, the overweight and obesity epidemic in the USA has resulted in a significant health and economic burden. Understanding current trends and future trajectories at both national and state levels is crucial for assessing the success of existing interventions and informing future health policy changes. …”
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Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease by Nour K. Majbour (8809316)

“…CSF total α-syn (t-α-syn) significantly increased in the AD group (p < 0.0001) compared to controls, while oligomeric- and phosphorylated-Ser129-α-syn did not change significantly. …”

Effective Approach for Increasing the Heteroatom Doping Levels of Porous Carbons for Superior CO2 Capture and Separation Performance by Abdelmoaty, Yomna H

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Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system by Frank Schmidt (207186)

“…<h3>Background</h3><p dir="ltr">Coronavirus disease (COVID-19) manifests many clinical symptoms, including an exacerbated immune response and cytokine storm. …”

Increasing consultant-level staffing as a proportion of overall physician coverage improves emergency department length of stay targets by Dominic Jenkins (9983446)

Increased MicroRNA Levels in Women With Polycystic Ovarian Syndrome but Without Insulin Resistance: A Pilot Prospective Study by Alexandra E. Butler (6189536)

Air pollution burden of disease over highly populated states in the Middle East by Rima J. Isaifan (8350056)

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”

Circulating lipid levels and risk of coronary artery disease in a large group of patients undergoing coronary angiography by Deeb, Mary E.

“…In conclusion, low levels of HDL-cholesterol and high levels TC/HDL-C ratio are strong biological markers of disease occurrence and severity in the Lebanese population.…”
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Significance of Avicennia Marina in the Arabian Gulf Environment: A Review by Kaiprath Puthiyapurayil Haseeba (21392966)

“…However, in the past two decades Gulf mangroves have been facing significant threats, including extensive coastal development, shoreline modification by establishing marinas and ports, and climate change-associated impacts such as sea-level rise and altered precipitation patterns, which pose significant risks to this fragile ecosystem. …”

Cardiac phosphodiesterases are differentially increased in diabetic cardiomyopathy by Hanna, Rita

“…Upregulation of β1-AR receptor transcripts was noted in diabetic hearts at 4 weeks along with an increase in cAMP levels and an upregulation in the ejection fraction and fraction shortening. …”
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Revisiting high-density lipoprotein cholesterol in cardiovascular disease: Is too much of a good thing always a good thing? by Mohammad Al Zein (20090700)

“…Furthermore, evidence from epidemiological and genetic studies reveals that not only low HDL-C levels, but also very high levels of HDL-C are linked to increased risk of CVD. …”

Tumor-Infiltrating Lymphoid Cells in Colorectal Cancer Patients with Varying Disease Stages and Microsatellite Instability-High/Stable Tumors by Salman M. Toor (8854751)

“…We investigated the expression of immune checkpoints (ICs) on lymphoid populations within the CRC TME and compared with cells from normal colon tissues using samples from 50 patients with varying disease stages. We found that the levels of B cells, T cells, and NK cells were similar, IC-expressing CD4+ and CD4+CD8+ double positive T cells were higher, while CD8+ T cells and CD4−CD8− double negative T cells were significantly lower in CRC tumors. …”

Cyclosporine lymphocyte maximum level by Kilani, Halal E.

“…No significant difference was observed among the 3 groups with regard to CsA dosage, C0, Cmax, mycophenolate mofetil (MMF) dosage, and mycophenolic acid (MPA) plasma levels. …”
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Association of coronary artery disease and chronic kidney disease in Lebanese population by Milane, Aline

“…This correlation remained highly significant despite considerable inter-patient variability and was at its highest at the most advanced stages of both diseases. …”
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Disease-Associated α-Synuclein Aggregates as Biomarkers of Parkinson Disease Clinical Stage by Nour Majbour (3528548)

“…<h3>Background and Objectives</h3><p dir="ltr">Robust biomarkers that can mirror Parkinson disease (PD) are of great significance. In this study, we present a novel approach to investigate disease-associated α-synuclein (αSyn) aggregates as biomarkers of PD clinical stage.…”

Tryptophanyl-tRNA synthetase-1 (WARS-1) depletion and high tryptophan concentration lead to genomic instability in Caenorhabditis elegans by Mahmoud Izadi (12899508)

“…Our result demonstrates that exposing C. elegans to a high tryptophan dosage leads to DNA damage checkpoint activation and a significant increase in the tryptophan metabolites. …”

Stemming cardiovascular diseases in Qatar by Nature Research (16552612)

“…Many of the heart attack and stroke patients had diabetes, hypertension, high cholesterol, and/or were smokers, whereas controls were much less likely to have these factors.…”

National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050 by Marie, Ng

“…BackgroundOver the past several decades, the overweight and obesity epidemic in the USA has resulted in a significant health and economic burden. Understanding current trends and future trajectories at both national and state levels is crucial for assessing the success of existing interventions and informing future health policy changes. …”
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