Supplementary file 1_Pedunculoside targets P2X7R to protect against myocarditis by regulating the NLRP3/PIP2/MAPK signaling pathway.docx by Youqiong Zhuo (10361585)

“…</p>Results<p>We found that PE demonstrated inhibition of H9c2 cell death and decreased ROS, Ca²⁺ levels, and MMP loss induced by LPS + ATP. …”

Image 2_Horticultural performance and QTL mapping of snap bean (Phaseolus vulgaris L.) populations with organic and conventional breeding histories.jpeg by Hayley E. P. Richardson (21383333)

“…We also found that root branching density increased among organically-bred bean families, while root disease decreased in both the organically-bred bean families and the populations with ‘OR5630’ × ‘Black Valentine’ parentage. …”

Image 1_sodA modulates in vitro and in vivo virulence of Yersinia enterocolitica.jpeg by Yingying Zhang (42910)

“…</p>Results<p>The ΔsodA mutant exhibited significantly reduced adhesion to and invasion of epithelial cells, impaired survival within macrophages, and decreased colonization in murine ileum and colon tissues. …”

<b>RTA408 alleviates retinal ganglion cells damage in mouse glaucoma by inhibiting excessive autophagy</b> by Hongmei Qian (538647)

“…</p><p><br></p><p dir="ltr"><b>Results:</b> In glaucomatous mice, RTA408 significantly reduces the apoptosis levels of RGCs and decreases RGC loss. …”

Image 1_High-dose thiamine supplementation ameliorates obesity induced by a high-fat and high-fructose diet in mice by reshaping gut microbiota.tif by Yu Xia (8822)

“…Furthermore, oral administration of high-dose thiamine also regulated HFFD-induced gut microbiota dysbiosis by reshaping its structure and composition of gut microbiota, such as increasing the relative abundance of Actinobacteria and Bifidobacterium pseudolongum, and reducing the relative abundance of Proteobacteria and Ruminococcus gnavus, accompanied by decreased level of gut-derived endotoxin. Finally, significant correlations were found between obesity-related phenotypes and gut microbiota through correlation analysis.…”

Table 1_Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.xlsx by Xiaofang Guo (385478)

“…Contrary, the age-standardized DALY rate (ASDR) decreased in idiopathic epilepsy and multiple sclerosis. …”

Drawing test data. by Run-Zhi Jia (21262716)

“…As the confining pressure increased, the ratio of tensile cracks in rock sample failure decreased, while the ratio of shear cracks increased. …”

Video 1_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.mp4 by Sofie Vandendriessche (638514)

“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”

Economic resilience results. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Test results related to model selection. by Jie Huang (104235)

“…Spatially, the CCD demonstrates a characteristic pattern of decreasing from east to west. Overall, achieving a “cross-level transition” in CCD is challenging, and the neighboring provinces significantly influence the enhancement of local CCD. …”

Data Sheet 1_Sleep is enhanced in aged male mice that overexpress calcium/calmodulin-dependent protein kinase IV.docx by Sierra P. Feeney (21466928)

“…Conversely, female mice overexpressing CaMKIV displayed no significant differences in the percentage of time spent in each vigilance state compared to their wild-type counterparts, regardless of age. …”

Image 2_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif by Chandrasekar Karthika (21255878)

“…In vitro investigations demonstrated that the phage cocktail significantly decreased both planktonic and sessile cells. …”

Data Sheet 1_Assessing ecological environmental quality and conservation effectiveness in the World’s largest urban green heart using the remote sensing ecological index (RSEI) and... by Chongbo Wu (22135075)

“…The findings reveal that: (1) The RSEI demonstrated an average annual growth rate of 0.0038 years^-1 over 31 years, with significant increases during 1990–2013 (0.0045 years^-1) and 2013–2020 (0.0089 years^-1). (2) Comparing pre- and post-GH policy implementation periods (1990–2013 vs. 2013–2020), areas showing EEQ improvement increased from 77.15% to 89.69%, while areas with stable and decreased EEQ declined from 22.36% to 10.17%. (3) GH policy demonstrates substantial positive conservation effects, with both GH and the 3 km buffer zone exhibiting EEQ improvements. …”

Data Sheet 1_Acceptance of sexual attraction and its link to psychological distress and sexual offending among pedohebephilic clients: results from a preliminary analysis.pdf by Anna Konrad (20620994)

“…</p>Results<p>Compared to teleiophilic individuals, pedohebephilic individuals showed lower acceptance of their sexual interests. No significant differences were found between groups regarding past sexual offending. …”

Supplementary Material for: Effect of endobronchial valve treatment on skeletal muscles, fatigue, and sleep in severe emphysema patients by figshare admin karger (2628495)

“…Intercostal thickening fraction did not change following treatment. Fatigue decreased significantly, reducing severe fatigue prevalence from 70% to 25%. …”

Table 1_Salt tolerance characterization and genome-wide association study of Gossypium barbadense accessions reveal salinity-adaptive variations.xlsx by Huazu Li (22228792)

“…VIGS of GbXTH27 exacerbated salt-induced wilting phenotypes and significantly decreased antioxidant enzyme activities.…”

Supplementary file 1_Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.docx by Xiaofang Guo (385478)

“…Contrary, the age-standardized DALY rate (ASDR) decreased in idiopathic epilepsy and multiple sclerosis. …”

Data Sheet 1_Effects of simulated litter inputs on ecological niches and interspecific connectivity of alpine meadow plants.xlsx by Weishan Lin (20756891)

“…Introduction<p>Plant litter enters the soil as the main nutrient for alpine meadow ecosystems, and the amount of litter input has a significant effect on alpine meadow plant diversity, ecological niches, and interspecific connectivity.…”

<b><i>Assessment of Diseases’ Prevalence, Nutrition and Associated Factors in a Conflict-Affected Region: A Study in Leepa Valley, Azad Jammu and Kashmir, Pakistan</i></b> by Zoha Khan (19100603)

“…Moreover, 76.3% reported decreased employment opportunities in Leepa Valley due to the ongoing border conflicts. …”

Table 1_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xlsx by Guilin Ren (18720749)

“…</p>Results<p>HFD induced biochemical abnormalities and liver injury, which were significantly reversed by Pac, as evidenced by decreased plasma levels of AST (Aspartate aminotransferase), ALT (Alanine aminotransferase), TG (Triglyceride), and TC (Total cholesterol), and reduced hepatic TG and TC levels. …”