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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
higher decrease » higher degree (Expand Search), higher degrees (Expand Search), highest increase (Expand Search)
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19641
ABR wave I and IV parameters in response to clicks.
Published 2025“…The P1-N1 amplitude at 90 dB SPL (<b>A</b>) was significantly reduced two days post-trauma compared to pre-trauma and stayed decreased three weeks post-trauma. …”
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19642
Data Sheet 1_Variation and spread of resistomes in swine manure, manure slurries, and long-term manure-fertilized soils.docx
Published 2025“…High-risk ARG abundance significantly increased from 404.7 in manure to 843.2 in slurries, with health-risk scores rising 1.88-fold during anaerobic digestion. …”
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19643
Flow Chart of the Study Steps.
Published 2025“…</p><p>Conclusion</p><p>The IP-GBL enhanced germane cognitive load and decreased the intrinsic and extrinsic cognitive load, which facilitated students’ learning. …”
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19644
Protective effect of phosphoenolpyruvate carboxykinase 1 on inflammation and fibrotic progression of IgA nephropathy
Published 2025“…In experiments with SV40-transformed mouse glomerular mesangial cells (MCs), PCK1 and PPARγ protein expression levels were significantly decreased in polymeric IgA1 (pIgA1)-stimulated MCs, which contrasts with the increased expression of inflammatory and fibrotic factors. …”
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19645
Image 2_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif
Published 2025“…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …”
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19646
Image 5_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf
Published 2024“…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …”
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19647
Image 1_Mitochondrial DNA oxidation and content in different metabolic phenotypes of women with polycystic ovary syndrome.jpeg
Published 2025“…</p>Results<p>Our findings showed that patients with PCOS had decreased mtDNA content and increased oxidation damage. …”
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19648
Data Sheet 1_Pregnancy hormones increase cardiac capillary density via the PGC-1α/ERRα/VEGF pathway in cardiomyocytes.docx
Published 2025“…Background<p>Pregnancy significantly affects the maternal cardiovascular system, with physiological adaptations characterized by cardiac hypertrophy and increased capillarization. …”
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19649
Data Sheet 1_STING regulates NETs formation by activating GSDMD in influenza viral pneumonia.pdf
Published 2025“…Symptoms of pneumonia in STING-KO mice infected with PR8 were significantly milder than those in WT mice, and NETs were less likely to form in the lung tissue of STING-KO mice. …”
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19650
Table 1_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx
Published 2025“…However, the change in age-standardized rates from 1990 to 2021 declined significantly. The association between the Socio-demographic Index (SDI) and the burden of amputations in 2021 was not linear. …”
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19651
Table 3_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx
Published 2025“…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…”
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19652
Integrating legumes into cropping systems enhances soil carbon and nitrogen content while reduces the soil carbon-to-nitrogen ratio: A global meta-analysis
Published 2025“…Moreover, SOC and STN increased when legumes replaced fallow or gramineous soil, whereas SCN significantly decreased only when legumes replaced gramineous systems. …”
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19653
DataSheet1_Formulation development, characterization, and evaluation of sorafenib-loaded PLGA–chitosan nanoparticles.docx
Published 2024“…Pharmacokinetic parameters such as AUC<sub>0-t</sub>, C<sub>max</sub> MRT, Vd, and half-life (t<sub>1/2</sub>) were enhanced significantly (p ≤ 0.001), while clearance was considerably decreased (p ≤ 0.001) for the chosen synthesized nanoparticles in contrast to the commercially accessible sorafenib formulation (Nexavar<sup>®</sup>). …”
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19654
Supplementary file 1_The efficacy of resveratrol in the treatment of liver fibrosis: a systematic review and meta-analysis of preclinical studies.docx
Published 2025“…</p>Conclusion<p>Resveratrol significantly alleviates liver fibrosis in animal models via anti-inflammatory and antioxidant mechanisms. …”
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19655
Image 1_Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses.pdf
Published 2024“…Salmonella dissemination to the spleen was significantly reduced by both vaccines. Gene expression of intestinal transporters (such as SCNN1B and SLC10A2) and tight junction proteins was significantly decreased in the turkey cecal tonsil transcriptome at 2 DPI with S. …”
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19656
Roxadustat alleviates cisplatin-induced acute kidney injury by regulating fatty acid oxidation and mitochondrial function
Published 2025“…Roxadustat also remarkably decreased the expression of KIM-1 and NGAL. Furthermore, roxadustat significantly abolished the expression of Bax and cleaved caspase 3, two apoptosis marker proteins. …”
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19657
Table 4_Outcomes after liposuction-based treatment of lymphedema: a systematic review and meta-analysis.docx
Published 2025“…Combined approaches achieved slightly lower reductions (87.31%), but significantly decreased compression dependence, improved lymphatic function, and enhanced QOL. …”
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19658
Table 1_Evaluation of a multi-epitope vaccine PME for Pasteurella multocida in mouse model.docx
Published 2025“…Furthermore, the pathological lung damages in the His-PME group and the pcDNA3.1-PME group were significantly alleviated, and the bacterial loads in lung tissues were significantly decreased. …”
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19659
Supplementary file 1_Application of multidimensional gait feature fusion algorithm in gait assessment for patients with knee osteoarthritis.docx
Published 2025“…The incorporation of multidimensional features significantly enhanced the performance of all classification models: under multidimensional feature input, RF, SVM, DT, and KNN achieved accuracies of 96.93%, 92.44%, 90.29%, and 88.98%, respectively—all significantly outperforming models using single‐dimensional features.…”
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19660
Image_3_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG
Published 2025“…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”