Data Sheet 1_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through a... by Jiaochen Luan (9704384)

“…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”

Heart looping variations in <i>Notch3</i> and <i>Nodal</i> compound mutants. by Tobias Holm Bønnelykke (20968460)

“…(<b>F</b>) Brightfield images of wild type (f1), control <i>Notch3</i> heterozygote (f2) compared to homozygote <i>Nodal</i> mutants with decreased <i>Notch3</i> (f3) at E9.5, in a ventral view. …”

supplementary figure: Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma by Takuto Itano (16830105)

“…(right): Self-renewal capacity of RD and AD-RD cells assessed by a sphere formation assay (n = 4). Statistical significance: ****p < 0.0001. c (top): Immunoblots from in vitro kinase assays treated with hit compounds and with EGFR inhibitors. …”

Figure 7 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma by Elisabet Figuerola-Bou (22618659)

“…<p>KDM6B KO decreases tumor growth. <b>A,</b> Colony formation assay of KDM6B KO cells (sgRNA#1 and sgRNA#2) compared with parental and sgCTRL A-673 cells. …”

Image 3_MR-guided focused ultrasound thalamotomy modulates cerebello-thalamo-cortical tremor network in essential tremor patients.png by Li Jiang (120930)

“…Conversely, a significant positive correlation was observed in the frontal orbital cortex, right insular cortex, temporal pole, hippocampus, left lingual gyrus, right cerebellar lobules IV/V, left cerebellar lobule VI, and vermis IV/V.…”

Table 1_MR-guided focused ultrasound thalamotomy modulates cerebello-thalamo-cortical tremor network in essential tremor patients.docx by Li Jiang (120930)

“…Conversely, a significant positive correlation was observed in the frontal orbital cortex, right insular cortex, temporal pole, hippocampus, left lingual gyrus, right cerebellar lobules IV/V, left cerebellar lobule VI, and vermis IV/V.…”

Image 2_MR-guided focused ultrasound thalamotomy modulates cerebello-thalamo-cortical tremor network in essential tremor patients.png by Li Jiang (120930)

“…Conversely, a significant positive correlation was observed in the frontal orbital cortex, right insular cortex, temporal pole, hippocampus, left lingual gyrus, right cerebellar lobules IV/V, left cerebellar lobule VI, and vermis IV/V.…”

Image 1_MR-guided focused ultrasound thalamotomy modulates cerebello-thalamo-cortical tremor network in essential tremor patients.jpeg by Li Jiang (120930)

“…Conversely, a significant positive correlation was observed in the frontal orbital cortex, right insular cortex, temporal pole, hippocampus, left lingual gyrus, right cerebellar lobules IV/V, left cerebellar lobule VI, and vermis IV/V.…”

Protein and gene expression levels of p62 and LC3B in miR-7974 mimic-transfected MCF-7 cells. by Stralina Eneh (21213312)

“…<b>(B)</b> The fold change of p62 and <b>(C)</b> LC3BI between negative control/cell-only samples and miR-7974-treated samples were statistically significant. GAPDH was used as a reference protein. …”

Gene diversity of lancelet <i>Artemis.</i> by Ziwen Huang (17562948)

“…<p><b>(A)</b> Codons under positive selection pressure in lancelet Artemis with a posterior probability (<i>P</i>) identified by Bayes empirical Bayes (BEB) analysis. ( *<i>P</i> > 0.95, **<i>P</i> > 0.99). …”

Table 1_Disorders of acid-base balance promote rumen lipopolysaccharide biosynthesis in dairy cows by modulating the microbiome.xls by Guobin Hou (20207727)

“…Introduction<p>Disorders of acid-base balance in the rumen of dairy cows have a significant impact on their health and performance. …”

Data Sheet 1_Immunogenic cell death-related biomarkers in heart failure probed by transcriptome and single-cell sequencing.zip by Haoyue Wang (13138179)

“…In addition, the expression levels of CD163 and VSIG4 increased in subpopulations of monocytes and macrophages, whereas FPR1 showed a decreasing trend. RT-qPCR results confirmed significant down-regulation of CD163, FPR1, and VSIG4 in patients with HF and animal models.…”

Image 1_Disorders of acid-base balance promote rumen lipopolysaccharide biosynthesis in dairy cows by modulating the microbiome.jpeg by Guobin Hou (20207727)

“…Introduction<p>Disorders of acid-base balance in the rumen of dairy cows have a significant impact on their health and performance. …”

Additional file 2 of Evobrutinib mitigates neuroinflammation after ischemic stroke by targeting M1 microglial polarization via the TLR4/Myd88/NF-κB pathway by Yixiang Jiang (2580220)

“…Statistical analysis revealed no significant differences in CD80+ expression between MCAO and Evobrutinib group while the expression of MHCII+ microglia decreased in Evobrutinib group compared to MCAO. …”

Image1_In-situ analysis of polymetallic nodules from the clarion-Clipperton zone, Pacific Ocean: implication for controlling on chemical composition variability.jpeg by Jie Li (15030)

“…Analysis of Nodule BC06 from the eastern CCZ reveals a decreasing Mn/Fe ratio from the inner part (Layer I) to the outer part (Layer II). …”

Table1_In-situ analysis of polymetallic nodules from the clarion-Clipperton zone, Pacific Ocean: implication for controlling on chemical composition variability.xlsx by Jie Li (15030)

“…Analysis of Nodule BC06 from the eastern CCZ reveals a decreasing Mn/Fe ratio from the inner part (Layer I) to the outer part (Layer II). …”

Stepwise increments in stimulus amplitude alter the information content of post-EOD spike distributions. by Alejo Rodríguez-Cattáneo (19713314)

“…EOD_-3 to EOD_-1) and the right points to the Jensen-Shannon divergence between the distributions just before (EOD_-3 to EOD_-1) and just after (EOD₀ to EOD₂) the step for the same unit. Upper (A) and lower (B) rows correspond to experiments in which the stimulus was decreased and increased, respectively. …”

PTEN KD induces EMT in epithelial CRC cells. by Ahmed H. Ghobashi (12705573)

“…EZH2i treated EV and PTEN KD cells act as a control for decreased H3K27me3 levels. <b>(C)</b> H3K27me3 band quantification for untreated EV and PTEN KD in HT29 and LS174T cells in (B). …”

Data Sheet 1_Comparative transcriptomics of two petal variants reveals key functional genes underlying petal shape development in lotus (Nelumbo).zip by Jiaxin He (11256475)

“…Introduction<p>The lotus (Nelumbo Adans.) is a versatile plant that integrates ornamental beauty, culinary applications, medicinal benefits, ecological significance, and cultural symbolism. …”

Data Sheet 1_Spatial–temporal evolution and associated factors of older adult care institutions in Shanghai.xlsx by Xingxing Yin (7919447)

“…Older adult care institutions in Shanghai exhibit clear spatial clustering features, evolving from a central cluster to a pattern of one major center surrounded by multiple secondary centers. …”