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Data Sheet 1_Bio-functional hydrogel coated membranes to decrease T-cell exhaustion in manufacturing of CAR T-cells.docx
Published 2025“…Further, the killing potential of the resulting CAR T product was evaluated, finding improved in vitro cytolysis of target cells with lower variability with HCMs.</p>Discussion<p>These results demonstrate the importance of lower T-cell exhaustion in CAR T manufacturing and present significant opportunities to modulate T-cell phenotypes for cell therapy applications using engineered bioinspired materials that display combinations of co-stimulatory molecules.…”