Data Sheet 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Data_Sheet_2_Safety and efficacy of plasmapheresis in treatment of acute fatty liver of pregnancy—a systematic review and meta-analysis.docx by Sujata Siwatch (19867233)

“…Biochemical parameter analysis demonstrated significant improvement post-PP/PE treatment, including decreased bilirubin (MD: 8.30, 95% CI: 6.75 to 9.84), AST (MD: 107.25, 95% CI: 52.45 to 162.06), ALT (MD: 111.08, 95% CI: 27.18 to 194.97), creatinine (MD: 1.66, 95% CI: 1.39 to 1.93), and Prothrombin time (MD: 5.08, 95% CI: 2.93 to 7.22).…”

Video 4_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Video 3_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Video 7_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Image_2_Prognostic value of the Naples Prognostic Score in adult chronic obstructive pulmonary disease: NHANES 2005–2018.TIFF by Yue Kang (427523)

“…All-cause mortality [HR (95%CI), 1.68 (1.39–2.85)] and hypertension-related mortality [HR (95%CI), 67.64 (8.88–515.07)] of group 2 were significantly elevated.…”

DataSheet2_Mineral nutrition for Cannabis sativa in the vegetative stage using response surface analysis.docx by Patrick Yawo Kpai (20376234)

“…The optimum concentrations of total nitrogen, P, K, calcium, and sulfur in the cannabis leaves were 0.54, 0.073, 0.27, 0.56, and 0.38 mg g^-1, respectively. An increase in P and K concentrations decreased the magnesium concentration in the leaves, but it was unaffected by the increase in N concentration. …”

Supplementary Material for: Identifying novel inflammatory protein biomarkers and drug targets of inflammatory bowel disease by integrating Mendelian randomization, bioinformatics,... by Wang F. (3215361)

“…Moreover, genetically predicted CD40 (OR = 0.855, 95%CI = 0.801-0.912) decreased Crohn’s disease (CD) risk. Genetically predicted fibroblast growth factor 21 (FGF21) (OR = 1.259, 95%CI = 1.135-1.397) and 4E-BP1 (OR = 1.202, 95%CI = 1.088-1.327) increased CD risk. …”

Proteomic and Functional Analysis on Endothelial Cell Heterogeneity Identifies Key Regulators in Hyperglycemia-Induced Dysfunction-Supplemental Materials by Morgan Minjares (21143203)

“…Furthermore, under high glucose conditions, WARS1 was increased while SOD2 was decreased. Reversing WARS1 or SOD2 expression levels improved HDMVEC migration and permeability functions. …”

Table2_Mechanism of abscisic acid in promoting softening of postharvest ‘Docteur Jules Guyot’ pear (Pyrus communis L.).xlsx by Xiaofei Xu (109890)

“…The cell wall disassembly-related genes PcPME3, PcPG1, PcPG2, PcPL, PcARF2, and PcGAL1, as well as ABA biosynthesis-related genes PcNCED1 and PcNCED2, were also significantly induced by ABA. …”

Beta Diversity and Differential Abundance Analysis of Gut Microbiota after FVT. by Melany Cervantes-Echeverría (22794116)

“…The blue bars indicate taxa significantly increased, while the red bars indicate taxa significantly decreased in the FVT compared to the control. …”

Supplementary Material for: Effect of gonadotropin dose reduction during COH on progesterone levels and embryo outcomes in women undergoing IVF/ICSI-ET with GnRH-A protocol by figshare admin karger (2628495)

“…The proportion of patients with P ≥ 1.5 ng/ml was significantly lower in the gonadotropin dose reduction group compared to the control group (22.7% vs. 29.9%, P=0.003).Multivariable logistic regression indicated that dose reduction decreased the risk of progesterone elevation [OR=0.535, 95% CI: 0.404-0.709]. …”

N-doped TiO₂ with stable surface Ti³⁺ for visible light photocatalytic hydrogen production by Jieming Chen (386865)

“…<p>Pure TiO₂ exhibits limited responsiveness to visible light, while the doping of Ti³⁺ significantly enhances its absorption efficiency in the visible spectrum, improving the efficiency of photogenerated electron utilization. …”

Data_Sheet_4_Oral swabs as a proxy for direct ruminal microbiome sampling in Holstein dairy cows is correlated with sample color.PDF by Joseph H. Skarlupka (5830637)

“…Our analysis of the fungal microbiome found that swabs with increasing darkness scores were associated with decreased alpha diversity (p < 0.05) and were also significantly associated with the ruminal solids fungal community, but not with the ruminal liquid community. …”

Data_Sheet_7_Oral swabs as a proxy for direct ruminal microbiome sampling in Holstein dairy cows is correlated with sample color.PDF by Joseph H. Skarlupka (5830637)

“…Our analysis of the fungal microbiome found that swabs with increasing darkness scores were associated with decreased alpha diversity (p < 0.05) and were also significantly associated with the ruminal solids fungal community, but not with the ruminal liquid community. …”

Data_Sheet_3_Oral swabs as a proxy for direct ruminal microbiome sampling in Holstein dairy cows is correlated with sample color.PDF by Joseph H. Skarlupka (5830637)

“…Our analysis of the fungal microbiome found that swabs with increasing darkness scores were associated with decreased alpha diversity (p < 0.05) and were also significantly associated with the ruminal solids fungal community, but not with the ruminal liquid community. …”

Table_2_Oral swabs as a proxy for direct ruminal microbiome sampling in Holstein dairy cows is correlated with sample color.XLSX by Joseph H. Skarlupka (5830637)

“…Our analysis of the fungal microbiome found that swabs with increasing darkness scores were associated with decreased alpha diversity (p < 0.05) and were also significantly associated with the ruminal solids fungal community, but not with the ruminal liquid community. …”

Data_Sheet_7_Oral swabs as a proxy for direct ruminal microbiome sampling in Holstein dairy cows is correlated with sample color.PDF by Joseph H. Skarlupka (5830637)

“…Our analysis of the fungal microbiome found that swabs with increasing darkness scores were associated with decreased alpha diversity (p < 0.05) and were also significantly associated with the ruminal solids fungal community, but not with the ruminal liquid community. …”

Data_Sheet_5_Oral swabs as a proxy for direct ruminal microbiome sampling in Holstein dairy cows is correlated with sample color.PDF by Joseph H. Skarlupka (5830637)

“…Our analysis of the fungal microbiome found that swabs with increasing darkness scores were associated with decreased alpha diversity (p < 0.05) and were also significantly associated with the ruminal solids fungal community, but not with the ruminal liquid community. …”

Data_Sheet_3_Oral swabs as a proxy for direct ruminal microbiome sampling in Holstein dairy cows is correlated with sample color.PDF by Joseph H. Skarlupka (5830637)

“…Our analysis of the fungal microbiome found that swabs with increasing darkness scores were associated with decreased alpha diversity (p < 0.05) and were also significantly associated with the ruminal solids fungal community, but not with the ruminal liquid community. …”