Search alternatives:
significantly i » significantly _ (Expand Search), significantly high (Expand Search), significantly less (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
i decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
significantly i » significantly _ (Expand Search), significantly high (Expand Search), significantly less (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
i decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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Y-27632 collaborated with BA to attenuate the increase in the integrity and decrease in the permeability of epithelial barrier injury induced by LPS in Caco2 monolayers.
Published 2024“…<p>(<b>A)</b> Y-27632 collaborated with BA to attenuate the effect of LPS on TEER in Caco2 cells on days 1–22. …”
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Raw data of Figs 1–6 in this study.
Published 2025“…When gut epithelial PGAM5 receptor and apoptosis were inhibited by PGAM5-specific siRNA, inhibitor (LFHP-1c) and apoptosis inhibitor (Z-VAD-FMK), trans-epithelial electrical resistance (TEER) and TJs expression were obviously increased, and intestinal permeability was evidently decreased. …”
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Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx
Published 2025“…Overall, from the 23 tested compounds, 15 showed the expected outcome, i.e., the compound led to a decrease of the TEER for the positive control compounds, or the TEER value remained stable after treatment with non-GI-toxic compounds.…”
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S1 File -
Published 2024“…Compared with LPS treatment alone, BA significantly mitigated the reduction in the TEER, decreased FD-4 flux permeability, increased the mRNA expression of ZO-1 and Occludin, and normalized the distribution of ZO-1 and Occludin in Caco2 cells. …”
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Experimental treatments and groups.
Published 2024“…Compared with LPS treatment alone, BA significantly mitigated the reduction in the TEER, decreased FD-4 flux permeability, increased the mRNA expression of ZO-1 and Occludin, and normalized the distribution of ZO-1 and Occludin in Caco2 cells. …”
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Primers for RT-qPCR.
Published 2024“…Compared with LPS treatment alone, BA significantly mitigated the reduction in the TEER, decreased FD-4 flux permeability, increased the mRNA expression of ZO-1 and Occludin, and normalized the distribution of ZO-1 and Occludin in Caco2 cells. …”
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Data Sheet 1_Cynaroside ameliorates TNBS-induced colitis by inhibiting intestinal epithelial cell apoptosis via the PI3K/AKT signalling pathway.pdf
Published 2025“…Combining network pharmacology prediction analysis with our validation data from animal models and colonic organoids, we demonstrated that Cyn significantly inhibits IEC apoptosis, as indicated by a decrease in the proportion of TUNEL-positive cells and changes in apoptosis-related protein levels. …”