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FIP1L1- platelet-derived growth factor receptor A -positive chronic eosinophilic leukemia showing dramatic response to imatinib
Published 2021“…</p><h3>Conclusion</h3><p dir="ltr">This case indicates that in the era of Tyrosine Kinase inhibitors such as imatinib, the prognosis of Eosinophilia associated with <i>FIP1L1-PDGFRA</i> rearrangement has significantly improved And Prompt treatment with imatinib can lead to complete hematological response and resolution of any organ damage involved with this disease.…”
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Successful bone marrow transplantation in a patient with Omenn syndrome, a rare variant of severe combined immunodeficiency syndrome: A case report
Published 2024“…Emphasis on newborn screening and multidisciplinary care improves outcomes for infants with inherited disorders. …”
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Phosphorus supplement alters postprandial lipemia of healthy male subjects
Published 2014“…Phosphorus (P) is reported to improve insulin sensitivity, which is involved in lipid metabolism, and thus we were interested in determining the impact of phosphorus ingestion on postprandial lipemia, a recognized CVD risk factor. …”
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125
Application of Data Mining to Predict and Diagnose Diabetic Retinopathy
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Effect of Hydroxycut Intake on Fasted and Postprandial Lipemia in Rats
Published 2015“…Regardless of fat content in the diet, the doses of hydroxycut used significantly decreased fasting serum concentrations of cholesterol, triacylglycerol (TAG), low-density lipoprotein (LDL) cholesterol, total apolipoprotein B (apo B), and LDL/high-density lipoprotein (HDL) cholesterol ratio. …”
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128
Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
Published 2024“…Results indicate that AuNPs treatment significantly impacted several metabolic pathways. Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. …”
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In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model
Published 2024“…Our findings demonstrated that the NO-RPs improved the survival rate in the heart failure zebrafish model and reversed heart failure by enhancing blood flow perfusion in Zebrafish embryos, significantly. …”
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130
Transfer learning for genotype–phenotype prediction using deep learning models
Published 2022“…If the large population data is extensive compared to small population data, expect transfer learning results to improve significantly. We show that Transfer learning is capable to create powerful models for genotype-phenotype predictions in large, well-studied populations and fine-tune these models to populations were data is sparse.…”
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131
Comprehensive analysis of LncRNAs expression profiles in an in vitro model of steatosis treated with Exendin-4
Published 2021“…Here, we sought to identify the long non-coding RNAs (LncRNAs) associated with the steatosis improvement induced by the GLP-1R agonist Exendin-4 (Ex-4) in vitro.…”
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Impacts of COVID-19 pandemic on environment, society, and food security
Published 2023“…<p dir="ltr">Coronavirus disease (COVID)-19 is a viral and transferable disease caused by severe respiratory syndrome-coronavirus-2. …”
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Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases
Published 1983“…This incidence was significantly higher than the calculated probability of the two diseases occurring by chance in the same patient. …”
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Neonatal autoimmune lymphoproliferative syndrome with a novel pathogenic homozygous FAS variant effectively treated with sirolimus: Case report
Published 2023“…Treatment with sirolimus effectively improved the patient clinical manifestations with obvious reduction in the percentage of DNTs.…”
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The Role of Government Hospital During the COVID-19 Pandemic
Published 2024“…Additionally, 20 Powered Air Purifying Respirators significantly enhanced healthcare workers' safety.</p><h3>Conclusion</h3><p dir="ltr">The comprehensive strategy, and strict infection prevention measures, significantly improved patient care and healthcare workers’ safety during the COVID-19 response. …”
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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
Published 2023“…MALAT1 has recently attracted attention for its role in the evolution of diabetic complications, since it has been demonstrated that MALAT1 dysregulation contributes to the pathogenesis of diabetes and liver disease. </p> <p>Objective: The purpose of this study was to investigate MALAT1's effects on hepatic lipid accumulation and potential targets in presence of the GLP-1R agonist Exendin-4 (Ex-4), which has the potential to improve steatosis and even steatohepatitis.…”
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In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model
Published 2024“…Our findings demonstrated that the NO-RPs improved the survival rate in the heart failure zebrafish model and reversed heart failure by enhancing blood flow perfusion in Zebrafish embryos, significantly. …”
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Carotenoids in Cancer Apoptosis—The Road from Bench to Bedside and Back
Published 2020“…However, this deficiency can be improved by using nanotechnological approaches, solid dispersions, microemulsions or biofortification that significantly increase the anti-cancer and pro-apoptotic efficacy of carotenoids. …”
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Benefit of consolidative radiation therapy in patients with diffuse large B-cell lymphoma treated with R-CHOP chemotherapy
Published 2010“…Conclusion This study showed significant improvements in OS and PFS among patients who received consolidation RT after R-CHOP chemotherapy for DLBCL.…”
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