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121
FIP1L1- platelet-derived growth factor receptor A -positive chronic eosinophilic leukemia showing dramatic response to imatinib
Published 2021“…</p><h3>Conclusion</h3><p dir="ltr">This case indicates that in the era of Tyrosine Kinase inhibitors such as imatinib, the prognosis of Eosinophilia associated with <i>FIP1L1-PDGFRA</i> rearrangement has significantly improved And Prompt treatment with imatinib can lead to complete hematological response and resolution of any organ damage involved with this disease.…”
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122
Phosphorus supplement alters postprandial lipemia of healthy male subjects
Published 2014“…Phosphorus (P) is reported to improve insulin sensitivity, which is involved in lipid metabolism, and thus we were interested in determining the impact of phosphorus ingestion on postprandial lipemia, a recognized CVD risk factor. …”
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Safety and efficacy of ensifentrine in COPD: A systemic review and meta-analysis
Published 2024“…<h3>Background</h3><p dir="ltr"><u>Chronic obstructive pulmonary disease </u>(COPD) significantly impacts global health due to persistent airflow limitation and inflammation. …”
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Application of Data Mining to Predict and Diagnose Diabetic Retinopathy
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Effect of Hydroxycut Intake on Fasted and Postprandial Lipemia in Rats
Published 2015“…Regardless of fat content in the diet, the doses of hydroxycut used significantly decreased fasting serum concentrations of cholesterol, triacylglycerol (TAG), low-density lipoprotein (LDL) cholesterol, total apolipoprotein B (apo B), and LDL/high-density lipoprotein (HDL) cholesterol ratio. …”
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Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
Published 2024“…Results indicate that AuNPs treatment significantly impacted several metabolic pathways. Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. …”
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In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model
Published 2024“…Our findings demonstrated that the NO-RPs improved the survival rate in the heart failure zebrafish model and reversed heart failure by enhancing blood flow perfusion in Zebrafish embryos, significantly. …”
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129
Transfer learning for genotype–phenotype prediction using deep learning models
Published 2022“…If the large population data is extensive compared to small population data, expect transfer learning results to improve significantly. We show that Transfer learning is capable to create powerful models for genotype-phenotype predictions in large, well-studied populations and fine-tune these models to populations were data is sparse.…”
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130
Impacts of COVID-19 pandemic on environment, society, and food security
Published 2023“…<p dir="ltr">Coronavirus disease (COVID)-19 is a viral and transferable disease caused by severe respiratory syndrome-coronavirus-2. …”
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131
Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases
Published 1983“…This incidence was significantly higher than the calculated probability of the two diseases occurring by chance in the same patient. …”
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Neonatal autoimmune lymphoproliferative syndrome with a novel pathogenic homozygous FAS variant effectively treated with sirolimus: Case report
Published 2023“…(lle259*). Sirolimus significantly reduced DNTs and substantially relieved the patient’s clinical symptoms.…”
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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
Published 2023“…MALAT1 has recently attracted attention for its role in the evolution of diabetic complications, since it has been demonstrated that MALAT1 dysregulation contributes to the pathogenesis of diabetes and liver disease. </p> <p>Objective: The purpose of this study was to investigate MALAT1's effects on hepatic lipid accumulation and potential targets in presence of the GLP-1R agonist Exendin-4 (Ex-4), which has the potential to improve steatosis and even steatohepatitis.…”
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The Role of Government Hospital During the COVID-19 Pandemic
Published 2024“…Additionally, 20 Powered Air Purifying Respirators significantly enhanced healthcare workers' safety.</p><h3>Conclusion</h3><p dir="ltr">The comprehensive strategy, and strict infection prevention measures, significantly improved patient care and healthcare workers’ safety during the COVID-19 response. …”
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In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model
Published 2024“…Our findings demonstrated that the NO-RPs improved the survival rate in the heart failure zebrafish model and reversed heart failure by enhancing blood flow perfusion in Zebrafish embryos, significantly. …”
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Reduction of laboratory utilization in the intensive care unit
Published 2016“…Intensive care unit morbidity and mortality were not impacted. Conclusion: A simple technique of resident, nursing, and ancillary staff education, combined with alterations in order sets using electronic medical records, can lead to a sustained reduction in laboratory test utilization over time and to significant cost savings without affecting patient safety.…”
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Carotenoids in Cancer Apoptosis—The Road from Bench to Bedside and Back
Published 2020“…However, this deficiency can be improved by using nanotechnological approaches, solid dispersions, microemulsions or biofortification that significantly increase the anti-cancer and pro-apoptotic efficacy of carotenoids. …”
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Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery
Published 2010“…Initially, concentrations were highest in heart and liver, but within 24 h they decreased significantly. From 24 h to 7 days, concentrations remained highest in tumors, regardless of whether they received US or not. …”
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Benefit of consolidative radiation therapy in patients with diffuse large B-cell lymphoma treated with R-CHOP chemotherapy
Published 2010“…Conclusion This study showed significant improvements in OS and PFS among patients who received consolidation RT after R-CHOP chemotherapy for DLBCL.…”
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