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impacted » impact (Expand Search), impacts (Expand Search)
decrease » increase (Expand Search)
improves » improve (Expand Search), improved (Expand Search)
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Effect of Hydroxycut Intake on Fasted and Postprandial Lipemia in Rats
Published 2015“…Regardless of fat content in the diet, the doses of hydroxycut used significantly decreased fasting serum concentrations of cholesterol, triacylglycerol (TAG), low-density lipoprotein (LDL) cholesterol, total apolipoprotein B (apo B), and LDL/high-density lipoprotein (HDL) cholesterol ratio. …”
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Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
Published 2024“…Results indicate that AuNPs treatment significantly impacted several metabolic pathways. Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. …”
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Comprehensive analysis of LncRNAs expression profiles in an in vitro model of steatosis treated with Exendin-4
Published 2021“…<h3>Background and aims</h3><p dir="ltr">The hallmark of non-alcoholic fatty liver disease (NAFLD) is the excessive hepatic lipid accumulation. …”
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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
Published 2023“…MALAT1 has recently attracted attention for its role in the evolution of diabetic complications, since it has been demonstrated that MALAT1 dysregulation contributes to the pathogenesis of diabetes and liver disease. </p> <p>Objective: The purpose of this study was to investigate MALAT1's effects on hepatic lipid accumulation and potential targets in presence of the GLP-1R agonist Exendin-4 (Ex-4), which has the potential to improve steatosis and even steatohepatitis.…”
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Reduction of laboratory utilization in the intensive care unit
Published 2016“…Intensive care unit morbidity and mortality were not impacted. Conclusion: A simple technique of resident, nursing, and ancillary staff education, combined with alterations in order sets using electronic medical records, can lead to a sustained reduction in laboratory test utilization over time and to significant cost savings without affecting patient safety.…”
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Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery
Published 2010“…Initially, concentrations were highest in heart and liver, but within 24 h they decreased significantly. From 24 h to 7 days, concentrations remained highest in tumors, regardless of whether they received US or not. …”
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Quality of life, Knowledge and Access to Treatment in Times of Economic crisis in Lebanon
Published 2023“…Background Multiple sclerosis (MS) is a degenerative disease of the central nervous system that can lead to lifelong disabilities, and thus, significantly impacts patient's quality of life. …”
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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
Published 2015“…In the presence of arachidonic acid, additional eicosanoids generated by 12/15-LOX, including 12- and 11-HETEs, were significantly increased. Fluorescein angiography and retinal albumin leakage showed a significant decrease in retinal hyperpermeability in streptozotocin-induced diabetic mice lacking 12/15-LOX compared with diabetic WT mice. …”
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Radiation treatment outcomes for unresectable hepatocellular carcinoma
Published 2011“…One-year in-field progression-free survival rate (60% vs. 88%) and biochemical progression-free survival duration (median 6.5 vs. 1.6 months) were also significantly improved in patients treated to a biologically effective dose ≥75. …”
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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Successful bone marrow transplantation in a patient with Omenn syndrome, a rare variant of severe combined immunodeficiency syndrome: A case report
Published 2024“…Emphasis on newborn screening and multidisciplinary care improves outcomes for infants with inherited disorders. …”
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DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
Published 2019“…However, the functional impact of such interaction on their activities has not been investigated. …”
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Geopolitical instability and environmental sustainability
Published 2025“…Geopolitical instability significantly impacts environmental sustainability, yet its role remains underexplored. …”
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Wave-packet dynamics in monolayer graphene with periodic scattering potentials
Published 2025“…We found that, despite the pronounced Klein <u>tunneling</u> effect in graphene, the presence of a lattice of defects significantly impacts the propagation properties of the wave packets. …”
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Mutational landscape of aggressive cutaneous squamous cell carcinoma
Published 2017“…Conclusions: The mutational spectrum of cSCC is similar to that of head and neck squamous cell carcinoma and dominated by tumor suppressor genes. These results improve the foundation for understanding this disease and should aid in identifying and treating aggressive cSCC.…”
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An Investigation into the factors influencing Arabic speaking students’ proficiency in the Arabic language in Dubai British School
Published 2022“…This is likely due to the difference in linguistic environment experienced by the students in the British schools, relative to those in the Arabic schools, and which this study significantly correlated with decreased proficiency. …”
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Clinical and Prognostic Implications of Plasma Insulin-Like Growth Factor-1 and Vascular Endothelial Growth Factor in Patients With Hepatocellular Carcinoma
Published 2011“…The study objective was to improve prognostic stratification of patients with HCC. …”
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