Effect of acute and chronic grapefruit, orange, and pineapple juice intake on blood lipid profile in normolipidemic rat. by Daher, Costantine F.

“…Background: High fruit intake is known to be associated with reduced riskof coronary heart disease. Our objective was to determine the effects of acute and chronic juice [grapefruit,orange, and pineapple] intake on plasma lipid profile and lipoprotein metabolism in normolipidemic rats.Material/Methods: The effects of acute juice intake were studied after three hours of a single juice-lipidload instilled intragastrically. …”
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COVID-19 and renal involvement: a prospective cohort study assessing the impact of mild SARS-CoV-2 infection on the kidney function of young healthy males by Khalid Al Rumaihi (14148804)

“…Changes in the renal function appear to be related to reduced creatinine clearance and possible albumin leakage in the acute phase of the disease. …”

Aortic stiffness, living donors, and renal transplantation by Bahous, Sola Aoun

“…In subjects with renal disease, reduced renal function and increased arterial stiffness are significantly associated in cross-sectional studies. …”
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Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line by Toutounji, Mohamad

“…The present study investigates endoplasmic reticulum (ER) stress in addition to alterations in protein and membrane trafficking in a dextran sulfate sodium (DSS)-induced IBD-like phenotype of intestinal Caco-2 cells in culture. DSS treatment significantly reduced the transepithelial electric resistance (TEER) and increased the epithelial permeability of Caco-2 cells, without affecting their viability. …”
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Effects of hydroxycut ingestion on the lipid profile & lipoproteine metabolism in the rat model. (c2004) by Khajag, Koulajian

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In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model by Maram Hasan (6672440)

“…Our findings demonstrated that the NO-RPs improved the survival rate in the heart failure zebrafish model and reversed heart failure by enhancing blood flow perfusion in Zebrafish embryos, significantly. In addition, RT-PCR results showed that the NO-RPs significantly reduced the expression of pro-inflammatory markers (lL-6&COX-2) in the heart failure zebrafish model. …”

Exploring the Fecal miRNA Profile in FMF Patients and the Role of miR-21-5p in Inflammatory Pathways Associated with FMF Pathogenesis by Chaaban, Ahlam

“…Correlation studies revealed that three anti-inflammatory miRNAs, mir-144-3p, mir-29b- 3p, and mir-374b-5p, were downregulated in M694V homozygous patients compared to those with other genotypes and six miRNAs were higher in patients with greater disease severity. The inhibition of mir-21-5p in LPS-stimulated THP-1 derived macrophages reduced the activation of NF-κB and inflammasome pathways. …”
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The effects of Salvia Officinalis leave on hyperlipidemia, glycemia, ulcer, inflammation, and bactericidal activity. (c2006) by Alayan, Iman

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Effect of Hydroxycut Intake on Fasted and Postprandial Lipemia in Rats by Daher, Costantine F.

“…Regardless of fat content in the diet, the doses of hydroxycut used significantly decreased fasting serum concentrations of cholesterol, triacylglycerol (TAG), low-density lipoprotein (LDL) cholesterol, total apolipoprotein B (apo B), and LDL/high-density lipoprotein (HDL) cholesterol ratio. …”
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Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels by Haya Al-Sulaiti (5449256)

“…Results indicate that AuNPs treatment significantly impacted several metabolic pathways. Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. …”

A GHRHR founder mutation causes isolated growth hormone deficiency type IV in a consanguineous Pakistani family by Safeer Ahmad (9079257)

“…</p><h3>Results</h3><p dir="ltr">All affected individuals presented with a short stature without gross skeletal anomalies and significantly reduced serum GH levels. Genetic mapping revealed a homozygous nonsense mutation [NM_000823:c.G214T:p.…”

Type II diabetes mellitus and hyperhomocysteinemia by Platt, Daniel E.

“…Results We found that Hc levels were significantly reduced among subjects with diabetes compared to those without diabetes when adjusted for all potential confounders (OR 0.640; 95% CI [0.44–0.92]; p = 0.0200). …”
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Challenges of morbid obesity in gynecological practice by Albert A. Opoku (17019078)

“…Obesity affects several aspects of health, with increased risks of cardiovascular disease, diabetes, metabolic syndrome, and several malignancies.…”

Impacts of COVID-19 pandemic on environment, society, and food security by Hafiz Mohkum Hammad (17541432)

“…Environmental pollution was significantly reduced due to lockdown during the COVID-19 period. …”

The Prevalence and Genetic Spectrum of Familial Hypercholesterolemia in Qatar Based on Whole Genome Sequencing of 14,000 Subjects by Ilhame Diboun (3522413)

“…<p dir="ltr">Familial hypercholesterolemia (FH) is an inherited disease characterized by reduced efficiency of low-density lipoprotein-cholesterol (LDL-C) removal from the blood and, consequently, an increased risk of life-threatening early cardiovascular complications. …”

Impact of COVID‑19 pandemic restrictions and subsequent relaxation on the prevalence of respiratory virus hospitalizations in children by Ahmed Abushahin (17337703)

“…</p><h3>Conclusion</h3><p dir="ltr">Our study showed reduced viral ALRTI hospitalizations in Qatar during the COVID-19 pandemic with reduced RSV detection. …”

Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases by Hirbli, K.

“…This incidence was significantly higher than the calculated probability of the two diseases occurring by chance in the same patient. …”
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Neonatal autoimmune lymphoproliferative syndrome with a novel pathogenic homozygous FAS variant effectively treated with sirolimus: Case report by Fawzia M. Elgharbawy (17045534)

“…(lle259*). Sirolimus significantly reduced DNTs and substantially relieved the patient’s clinical symptoms.…”

Development of a cancer metastasis-on-chip assay for high throughput drug screening by Lutfiye Yildiz Ozer (17732619)

“…Further experimental analysis showed that Imatinib enhanced endothelial barrier stability as measured by trans-endothelial electrical resistance and significantly reduced the trans-endothelial invasion activity of tumor cells. …”

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

“…Interestingly, knocking down MALAT1 significantly reduces the expression of CD36 in steatosis HepG2 cells in the presence of Ex-4. …”