Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer حسب Adviti Naik (673163)

"…Following <i>LDHC</i> knockdown, we observed an increase in the secretion of tumor-derived pro-inflammatory cytokines (IFN-γ, GM-CSF, MCP-1, CXCL1), a decrease in the soluble levels of tumor-derived immunosuppressive factors (IL-6, Gal-9) and reduced tumor cell surface PD-L1 expression. …"

Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice حسب Ayman, Alzu'bi

"…Our results revealed that the administration of AB-FUBINACA induced a significant impairment in recognition memory associated with histopathological changes in the hippocampus. …"
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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy حسب Jia-Zhen Wu (6844793)

"…<h3>Background</h3><p dir="ltr">Progressive accumulation of α-synuclein is a key step in the pathological development of Parkinson’s disease. Impaired protein degradation and increased levels of α-synuclein may trigger a pathological aggregation <i>in vitro</i> and <i>in vivo</i>. …"

Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice حسب Ayman Alzu'bi (18192898)

"…Our results revealed that the administration of AB-FUBINACA induced a significant impairment in recognition memory associated with histopathological changes in the hippocampus. …"

Performance analysis of a new PV array reconfiguration approach: Simulations and outdoor experiments under fixed and moving shadows حسب Abinisha Thiruchuthan (23073046)

"…<p dir="ltr">Partial shading can significantly impair photovoltaic (PV) array performance in large-scale systems, by reducing power output and increasing the complexity of wiring and maintenance. …"

Effect of Acute and Chronic Moderate Red or White Wine Consumption on Fasted and Postprandial Lipemia in the Rat حسب Daher, Costantine F.

"…Phospholipid and cholesterol contents of CM, but not very-low-density lipoprotein (VLDL), were increased, indicating enhanced liver bile secretion; however, a significant increase in plasma VLDL concentration was observed. …"
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Immunoprofile of childhood diabetes حسب Meritxell Espino-Guarch (15430868)

"…<p><strong>Poster by Meritxell Espino-Guarch (Sidra Medicine), Rana Nahas (Sidra Medicine), Taushif Khan (Sidra Medicine), Susi Huang (Sidra Medicine), Anna Halama (Weill Cornell Medicine-Qatar), Khalid Hussain (Sidra Medicine), and Nicholas van Panhuys (Sidra Medicine)</strong></p> <p>Background: The incidence of T2D has increased significantly in recent years and is characterized by impaired insulin secretion, glucose intolerance and hyperglycemia and is highly associated with a modern sedentary lifestyle and obesity. …"

Effect of acute and chronic moderate alcohol consumption on fasted and postprandial lipemia in the rat حسب Daher, Costantine F.

"…Similar conditions also results in increased total phospholipid and cholesterol content of CM but not of VLDL, indicating an enhanced liver bile secretion into the gut; however, a significant increase in plasma VLDL concentration is observed. …"
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Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death حسب Tohme, Sara

"…Scavenging ROS using NAC significantly decreases cell death but has minimal effect on autophagy activation, suggesting that the accumulation of ROS is downstream of autophagy activation but upstream of cell death. …"
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Longitudinal Study of Hypertensive Subjects With Type 2 Diabetes Mellitus حسب Bahous, Sola Aoun

"…Using cross-sectional regression models, a significant association was observed between higher education levels, lower levels of anxiety and depression, and reduced overall mortality in diabetic hypertensive subjects, while impaired renal function, a history of stroke and myocardial infarction, and increased alcohol and tobacco consumption were significantly associated with increased mortality. …"
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Relationship Between Hyperglycemia and Infection in Critically Ill Patients حسب Btaiche, Imad F.

"…Uncontrolled hyperglycemia may be associated with complications such as fluid and electrolyte disturbances and increased infection risk. Studies have demonstrated impairment of host defenses, including decreased polymorphonuclear leukocyte mobilization, chemotaxis, and phagocytic activity related to hyperglycemia. …"
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Assessment of treatment burden and its impact on quality of life in dialysis-dependent and pre-dialysis chronic kidney disease patients حسب Asmaa Al-mansouri (16931739)

"…<h3>Background</h3><p dir="ltr">The management of chronic kidney disease (CKD) and its complications places a significant burden on patients, resulting in impairment of their health-related quality of life (HR-QOL). …"

Loan guarantee, management earnings forecasts and cost of debt: evidence from Chinese manufacturing firms حسب Muhammad Bilal Khan (8960918)

"…However, a positive relationship between information asymmetry measures and loan guarantees is more pronounced, suggesting that loan guarantees reduce the significance of information asymmetry issues, which impair borrowing firms’ re-payment ability and increase the credit risk of guarantors and banks. …"

Numerical analysis of combustion characteristics and emissions of recycled flare gas in ethylene cracking furnaces حسب TurkiM. AL-Amoodi (22466536)

"…Introducing 10–20 % excess air enhances stability, but levels beyond 30 % impair <u>thermal efficiency</u>. Emission trends indicate methane-rich mixtures increase CO₂ and NO_x, while lighter mixtures reduce NOx but encounter stability challenges. …"

Exploring Ultra-Processed Foods: Impact on Satiety, Eating Patterns, Blood Glucose Levels and Food Addiction حسب Mamo, Tracy G.

"…Characterized by hyper-palatable ingredients and extensive processing, UPFs contribute to increased caloric intake, impaired satiety signals, and a higher prevalence of addictive-like eating behaviors. …"
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Health-related quality of life and its predictors among adults living with HIV/AIDS and receiving antiretroviral therapy in Pakistan حسب Ali Ahmed (2567584)

"…<h2>Background</h2> <p>Health-related quality of life (HRQoL) is considered to be the fourth 90 of UNAIDS 90-90-90 target to monitor the effects of combination antiretroviral therapy (ART). ART has significantly increased the life expectancy of people living with HIV/AIDS (PLWHA). …"

Growth hormone treatment modulates active ghrelin levels in rats حسب Haddad, Haytham

"…Genotropin treatment caused a dose dependent decrease in active ghrelin concentration in stomach, kidney and pancreas with a concomitant increase in plasma, and reaching significance at 20 and 100 µg/rat/day doses. …"
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Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans حسب Kirti S. Prabhu (4246144)

"…These alterations resulted in impaired cellular growth and caspase-dependent cell death. …"

Discovery of a novel cytokine signature for the diagnosis of autism spectrum disorder in young Arab children in Qatar حسب Wared Nour-Eldine (13904298)

"…Furthermore, we observed that elevated levels of IFN-γ (odds ratio (OR) = 1.823; 95% (confidence interval) CI = 1.206, 2.755; p = 0.004) and FGF-2 (OR = 2.528; 95% CI = 1.457, 4.385; p < 0.001) were significantly associated with increased odds of ASD, whereas reduced levels of eotaxin (OR = 0.350; 95% CI = 0.160, 0.765; p = 0.008) and HGF (OR = 0.220; 95% CI = 0.070, 0.696; p = 0.010) were significantly associated with lower odds of ASD relative to controls. …"

Speech and Language Disorders: A systematic review of corpora and future directions حسب Abeer Z. Al-Marridi (23059021)

"…<p>Speech and Language Disorders (SLDs) significantly impact social interaction, communication, and educational outcomes, making them a global health priority. …"