Table 1_The mitochondrial function of peripheral blood cells in cognitive frailty patients.docx by Li Qin (205731)

“…</p>Conclusion<p>Age, lower educational attainment, malnutrition, and depression are significant risk factors for CF. Moreover, mitochondrial dysfunction, characterized by decreased mtDNAcn, impaired respiratory function and increased ROS levels appears to be a critical phenotype of CF.…”

Table 1_The role of gut microbiota in modulating immune responses in chronic liver disease: a systematic review and meta-analysis.docx by Eyad Gadour (21375983)

“…In patients with chronic liver disease (CLD), alterations in gut microbiota have been linked to disease progression and impaired immune function. …”

Table 1_Case Report: Identification of a novel hemizygous CFAP47 variant in a primary ciliary dyskinesia patient with dual ciliary and flagellar defects.docx by Miao He (148269)

“…Experimental validation revealed significantly decreased CFAP47 mRNA levels in the patient’s sperm and the HEK293 cells transfected with mutant plasmid compared to controls, suggesting impaired transcript stability.…”

DataSheet1_Efferocytosis dysfunction in CXCL4-induced M4 macrophages: phenotypic insights in systemic sclerosis in vitro and in vivo.docx by Erwan Le Tallec (19834785)

“…In vivo, CXCL4 expression was increased in the lungs of both SSc-mouse models, along with elevated M4 markers, while efferocytosis of BLM-mice alveolar macrophages was decreased. In vitro, M4-MDMs exhibited reduced efferocytosis compared to M0-MDMs, notably attributable to lower CD36 receptor expression and impaired phagocytosis capacities, despite enhanced LAP. …”

Data Sheet 1_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.pdf by Yi Shen (152956)

“…Interestingly, in the population of over 29 years’ old, a significant interaction between obesity and impaired CRF for PAA was observed (p = 0.018; p = 0.026).…”

Table 2_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx by Yi Shen (152956)

“…Interestingly, in the population of over 29 years’ old, a significant interaction between obesity and impaired CRF for PAA was observed (p = 0.018; p = 0.026).…”

Table 1_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx by Yi Shen (152956)

“…Interestingly, in the population of over 29 years’ old, a significant interaction between obesity and impaired CRF for PAA was observed (p = 0.018; p = 0.026).…”

Data Sheet 2_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.pdf by Yi Shen (152956)

“…Interestingly, in the population of over 29 years’ old, a significant interaction between obesity and impaired CRF for PAA was observed (p = 0.018; p = 0.026).…”

Supplementary file 2_Histopathological examination and transcriptomic profiling reveal gossypol toxicity-responsive genes related to fertility in mice.docx by Teame Gereziher Mehari (11253141)

“…Introduction<p>Gossypol impairs reproduction in both sexes, inducing mitochondrial dysfunction, irregular cycles, and fewer ovarian follicles, leading to decreased fertility rates. …”

Supplementary file 1_Histopathological examination and transcriptomic profiling reveal gossypol toxicity-responsive genes related to fertility in mice.docx by Teame Gereziher Mehari (11253141)

“…Introduction<p>Gossypol impairs reproduction in both sexes, inducing mitochondrial dysfunction, irregular cycles, and fewer ovarian follicles, leading to decreased fertility rates. …”

Video 2_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4 by Adam Eckardt (20573576)

“…Impaired motor function was identified in the hindlimbs of Bet1L siRNA-injected rats. …”

Video 1_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4 by Adam Eckardt (20573576)

“…Impaired motor function was identified in the hindlimbs of Bet1L siRNA-injected rats. …”

Data Sheet 1_Wooden breast myopathy is characterized by satellite cell dysfunction and syndecan-4 shedding.pdf by Lucie Pejšková (20467025)

“…Moreover, we showed that SDC4 overexpression is linked to reduced proliferation in MuSCs and affected myogenesis. …”

LncRNA MCM3AP-AS1 protects against cerebral ischemia-reperfusion injury via targeting miR-27b-3p by Rouli Dai (17063211)

“…Furthermore, OGD/R treatment inhibited cell viability, increased apoptosis, and promoted inflammatory factors secretion, MCM3AP-AS1 reversed these effects, but miR-27b-3p significantly impaired this reversal. Mechanistically, MCM3AP-AS1 targeted miR-27b-3p.…”

Low temperature reduces byssus adhesion of highly invasive golden mussels: Influencing mechanisms and antifouling implications by Miaolian Zhang (21974951)

“…Our results showed that low-temperature exposures significantly reduced adhesion rates of golden mussels, primarily by limiting byssus production associated with impaired synthesis and secretion of byssal proteins and decreasing byssus breaking force. …”

Table 1_Impact of short-term (24 h) blood pressure variability on 30-days clinical outcomes of acute strokes at two tertiary hospitals in Dar-es-Salaam.docx by Ayubu Eliesikia Mashambo (22596824)

“…Hemorrhagic strokes (n = 27; 56.3%) demonstrated higher systolic and diastolic BP variability than ischemic strokes, though differences were not statistically significant. Impaired nocturnal dipping (day/night systolic BP ratio) was linked to poor outcomes in univariate analysis (p = 0.019) but lost significance in multivariate testing (p = 0.16). …”

Table 1_Integrated physiological and transcriptomic analyses elucidate the molecular mechanisms of exogenous melatonin-mediated salt tolerance in pomegranate (Punica granatum L.).x... by Yuanling Yang (22524785)

“…Concurrently, salt stress severely impaired photosynthetic performance: PSII maximum photochemical efficiency (F_V/F_M) decreased by 44.5%, actual photochemical efficiency (Y_II) and photochemical quenching (qP) were reduced, and non-photochemical quenching (NPQ) increased, indicating serious photoinhibition and energy wastage. …”

Alcohol perceptions and driving decisions among adolescents: Exploring the role of peer and parental influences in Virginia by Asmaa Namoos (21304297)

“…Additionally, parental alcohol-impaired driving was linked to decreased positive attitudes among adolescents toward driving under the influence (coefficient = −0.024, <i>P</i> = .000). …”

Supplementary Material for: Impact of the apolipoprotein E ε4 allele on cognition and omega-3 fatty acid levels in the plasma membrane of red blood cells in healthy elderly Japanes... by figshare admin karger (2628495)

“…The ratio of docosahexaenoic acid (DHA) to arachidonic acid was significantly decreased, and the erythrocyte eicosapentaenoic acid (EPA) and DHA levels tended to be reduced in APOE4 carriers. …”

Data Sheet 1_Andrographolide suppresses chondrosarcoma cell migration and invasion by inhibiting the PI3K/Akt/mTOR signaling pathway and activating autophagy.pdf by Chun-Fei Wu (22315444)

“…Wound healing and transwell assays demonstrated that Andro (5 and 20 μM) treatment significantly reduced the wound healing rate and impaired the migratory and invasive abilities of chondrosarcoma cells after 24 hours (p<0.05) compared to controls. …”