DataSheet_1_WASp Deficiency Selectively Affects the TCR Diversity of Different Memory T Cell Subsets in WAS Chimeric Mice.zip by Wenyan Li (255305)

“…Previous studies showed that TCR diversity in Wiskott–Aldrich Syndrome (WAS) patients was severely impaired, especially in the memory T cell populations. …”

DataSheet_1_PvML1 suppresses bacterial infection by recognizing LPS and regulating AMP expression in shrimp.docx by Yue Wang (65477)

“…The knockdown of PvML1 remarkably suppressed the clearance of bacteria in hemolymph and decreased the survival rate of infected shrimp. Meanwhile, the silencing of PvML1 severely impaired the expression of a few antimicrobial peptides (AMPs). …”

Data_Sheet_1_Delayed Impact of 2-Oxoadipate Dehydrogenase Inhibition on the Rat Brain Metabolism Is Linked to Protein Glutarylation.docx by Alexandra I. Boyko (12704918)

“…We hypothesize that systemic significance of OADH relies on its generation of glutaryl residues for protein glutarylation. …”

Table_1_NADPH and Mito-Apocynin Treatment Protects Against KA-Induced Excitotoxic Injury Through Autophagy Pathway.pdf by Na Liu (102929)

“…Compared with NADPH, the combination showed more significant neuroprotective effects, presenting more neurons survive and better motor function recovery. …”

Image_2_Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson’s disease reveal upregulation of oxidative phosphorylation-related genes associated with... by Lautaro Francisco Belfiori (17901602)

“…In contrast, C57- En1^+/− mice had no significant increase in axonal swellings or cell loss in SNpc at 16 weeks. …”

Image_1_Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson’s disease reveal upregulation of oxidative phosphorylation-related genes associated with... by Lautaro Francisco Belfiori (17901602)

“…In contrast, C57- En1^+/− mice had no significant increase in axonal swellings or cell loss in SNpc at 16 weeks. …”

Data_Sheet_1_Case report: Anti-ARHGAP26 autoantibodies in atypical dementia with Lewy bodies.pdf by Niels Hansen (537291)

“…Neuropsychological testing revealed impaired cognitive flexibility, figural memory, and verbal memory. …”

Table_1_Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson’s disease reveal upregulation of oxidative phosphorylation-related genes associated with... by Lautaro Francisco Belfiori (17901602)

“…In contrast, C57- En1^+/− mice had no significant increase in axonal swellings or cell loss in SNpc at 16 weeks. …”

Downregulation of SPTAN1 is related to MLH1 deficiency and metastasis in colorectal cancer by Anne Ackermann (6443975)

“…Knockdown of SPTAN1 in CRC cell lines demonstrated decreased cell viability, impaired cellular mobility and reduced cell-cell contact formation, indicating that SPTAN1 plays an important role in cell growth and cell attachment. …”

Table_2_Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson’s disease reveal upregulation of oxidative phosphorylation-related genes associated with... by Lautaro Francisco Belfiori (17901602)

“…In contrast, C57- En1^+/− mice had no significant increase in axonal swellings or cell loss in SNpc at 16 weeks. …”

Data_Sheet_1_Spontaneous physical functional recovery after hospitalization for COVID-19: insights from a 1 month follow-up and a model to predict poor trajectory.PDF by Oleksii Honchar (16620777)

“…Background<p>Long COVID syndrome has emerged as a new global healthcare challenge, with impaired physical performance being a prominent debilitating factor. …”

Image_1_Alteration in the Functional Organization of the Default Mode Network Following Closed Non-severe Traumatic Brain Injury.TIF by Muhammad Riddha Abdul Rahman (12300314)

“…Within the DMN nodes, decreased activations were detected in the left inferior parietal lobule, precuneus, and right superior frontal gyrus. …”

DataSheet1_Quanduzhong capsules for the treatment of grade 1 hypertension patients with low-to-moderate risk: A multicenter, randomized, double-blind, placebo-controlled clinical t... by Xuan Xu (781842)

“…After 4 weeks of treatment, there were no significant differences between the groups in terms of safety indicators (p > .05). …”

Table_2_Causal Relationship Between Lung Function and Atrial Fibrillation: A Two Sample Univariable and Multivariable, Bidirectional Mendelian Randomization Study.XLSX by Qiaoyun Zhang (11677849)

“…<p>Background: Observational studies have identified impaired lung function accessed by forced expiratory volume in one second (FEV1), forced vital capacity (FVC) or the ratio of FEV1 over FVC (FEV1/FVC) as an independent risk factor for atrial fibrillation (AF). …”

Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer” by Chanping You (9067448)

“…For palbociclib, a CDK4/6 inhibitor, AR activation induced RB1 polyubiquitination and degradation, diminishing RB1 levels—a key downstream target of CDK4/6—and thus impairing palbociclib efficacy. Chromatin immunoprecipitation (ChIP) sequencing identified 1,209 AR-regulated genes, with gene ontology (GO) analysis highlighting significant enrichment of ubiquitin-related genes. qPCR validation pinpointed TRIM37, an AR-regulated E3 ligase, as a mediator of RB1 degradation. …”

Table_1_Causal Relationship Between Lung Function and Atrial Fibrillation: A Two Sample Univariable and Multivariable, Bidirectional Mendelian Randomization Study.DOCX by Qiaoyun Zhang (11677849)

“…<p>Background: Observational studies have identified impaired lung function accessed by forced expiratory volume in one second (FEV1), forced vital capacity (FVC) or the ratio of FEV1 over FVC (FEV1/FVC) as an independent risk factor for atrial fibrillation (AF). …”

Image2_Exome sequencing confirms the clinical diagnosis of both joubert syndrome and klinefelter syndrome with keratoconus in a han Chinese family.JPEG by Xinhe Fang (9281324)

“…Keratoconus (KC) is a kind of genetically predisposed eye disease that causes blindness characterized by a dilated thinning of the central or paracentral cornea conically projected forward, highly irregular astigmatism, and severe visual impairment. Klinefelter syndrome is caused by an extra X chromosome in the cells of male patients, and the main phenotype is tall stature and dysplasia with secondary sex characteristics. …”

Image1_Exome sequencing confirms the clinical diagnosis of both joubert syndrome and klinefelter syndrome with keratoconus in a han Chinese family.JPEG by Xinhe Fang (9281324)

“…Keratoconus (KC) is a kind of genetically predisposed eye disease that causes blindness characterized by a dilated thinning of the central or paracentral cornea conically projected forward, highly irregular astigmatism, and severe visual impairment. Klinefelter syndrome is caused by an extra X chromosome in the cells of male patients, and the main phenotype is tall stature and dysplasia with secondary sex characteristics. …”

Ciliary pattern of paramecia depleted for TZ proteins. by Delphine Gogendeau (8566902)

“…DNAH2^RNAi cells present a percentage of short cilia slightly higher than the controls. Impairing ciliary beating of TMEM216^RNAi cells by DNAH2 decreases this percentage. …”

The RBPJ AOS variants show dysregulated Notch target gene expression when compared to WT RBPJ. by Ellen K. Gagliani (11478756)

“…(n ≥ 4, [***] P < 0.0001, [NS] not significant, unpaired Student’s t-test).</p>…”