Flexible Microfluidic Devices for Tunable Formation of Double Emulsion by Uditha Roshan (20841937)

“…This innovative approach significantly advances the field of droplet-based microfluidics, providing on-site, real-time tunability for the generation of double-emulsion droplets with high precision and reproducibility.…”

Image1_Characterization of GABAergic marker expression in prefrontal cortex in dexamethasone induced depression/anxiety model.jpeg by Ling Hu (374570)

“…Background<p>The pivotal responsibility of GABAergic interneurons is inhibitory neurotransmission; in this way, their significance lies in regulating the maintenance of excitation/inhibition (E/I) balance in cortical circuits. …”

Table 1_NLR (neutrophil to lymphocyte ratio), PLR (platelet to lymphocyte ratio), and SII (systemic immune-inflammation index) reflect disease activity and renal remission in patie... by Xiaohui Zhang (81778)

“…During the 12-month follow-up of induction therapy, NLR and PLR showed a decreasing trend. Both baseline NLR and SII were positively correlated with baseline UTP and serum creatinine (SCr) levels (r = 0.112-0.148, p< 0.05 for all). …”

Table 5_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.docx by Zhijian Zha (19451405)

“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”

Table 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx by Rong Su (2210740)

“…In vitro, the overexpression of miR-4739 in Huh-7 cells significantly induced SPP1⁺ macrophages, and the culture medium derived from SPP1⁺ macrophages further promoted the proliferation and migration of Huh-7 cells. …”

Figure 6 from Distant Metastases of Breast Cancer Resemble Primary Tumors in Cancer Cell Composition but Differ in Immune Cell Phenotypes by Laura Kuett (20493991)

“…<b>F</b> and <b>G,</b> Immune cell phenotypic cluster enrichment in each clinical breast cancer subtype (<b>F</b>) or metastasis-defined patient group (<b>G</b>) at metastatic sites compared with average metastasis composition by differential abundance testing. Circles display significantly enriched (red) or decreased (blue; FDR < 0.05; multiple testing correction with the Benjamin–Hochberg method) results, with size indicating the log-transformed fold change.  …”

Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip by Erli Wu (17785482)

“…</p>Results<p>scRNA-seq analysis revealed a decreased proportion of HGFs alongside enrichment of multiple PANoptosis-related pathways in PD samples. …”

DataSheet2_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf by Jianan Zhang (786459)

“…Up-regulation of DYNLT3 expression significantly inhibited tumor growth in a nude mouse model, while downregulation of DYNLT3 showed the opposite results. …”

DNA damage protecting effects of PEExCC. by Srabonti Saha (17452756)

“…The results demonstrated that higher doses (200 mg) of <i>C. chinense</i> methanol extract inhibited immune responses, whereas lower doses helped restore them. The extracts significantly decreased pro-inflammatory mediators and cytokines in LPS-activated macrophages. …”

Supplementary file 1_Oral bacterial community dynamics during induction of gingival inflammation.docx by Bart J. F. Keijser (16884185)

“…</p>Results<p>The study revealed pronounced microbial changes, particularly in supragingival plaque, where Leptotrichia and Prevotella increased while Streptococcus decreased. Alpha diversity significantly increased in supragingival plaque, tongue, and saliva during gingivitis induction, highlighting shifts in microbial complexity. …”

Table 3_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx by Jingjing Chen (293564)

“…</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …”

Table 1_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.docx by Jing Wang (6206297)

“…</p>Results<p>We found that, in addition to ACTR3C, 17 ARPs were significantly overexpressed in HCC compared with normal tissues. …”

<i>Salmonella </i>Typhimurium <i>StiP</i>-mediated upregulation of membrane protein Alx drives complement evasion via CFI-dependent C3b degradation by jin guan (21792620)

“…Invasive strains exhibited significantly enhanced serum resistance (>17-fold survival in 75% isolates) and HeLa cell invasive ability (minimum bacterial loads 3.93 × 10⁵ CFU/mL) compared to non-invasive strains (< 9.8-fold survival; maximum bacterial loads 1.47 × 10⁵ CFU/mL). …”

Image 5_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif by Meirong Feng (22089665)

“…</p>Conclusion<p>HBV-LC patients in Northwest China exhibit altered clinical indicators, gut microbial composition (reduced diversity, increased opportunistic pathogens, decreased beneficial species), and metabolic function. …”

Flexible Microfluidic Devices for Tunable Formation of Double Emulsion by Uditha Roshan (20841937)

“…This innovative approach significantly advances the field of droplet-based microfluidics, providing on-site, real-time tunability for the generation of double-emulsion droplets with high precision and reproducibility.…”

Image 5_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno... by Shao-jun Xu (11633956)

“…Accordingly, we developed the SNS staging and found that the OS and DFS were significantly different among patients at different stages (all P < 0.001). …”

Table 1_Moderating effects of a healthy lifestyle on the association of pre-metabolic syndrome with multiple chronic disease comorbidities.docx by Youqiong Xu (18161893)

“…PreMetS [OR = 1.38, 95%CI: 1.16–1.64] and MetS [OR = 1.61, 95%CI: 1.32–1.97] were associated with a significantly higher risk of multiple comorbidities compared with the normal population, and the risk of multiple comorbidities tended to increase as the number of metabolic disorder components increased (p < 0.001). …”

Glucagon-like peptide-1 receptor agonists, inflammation, and kidney diseases: evidence from Mendelian randomization by Yu-Xuan Yao (21338594)

“…</p> <p>After meta-analyses of both discovery and validation cohorts, genetically proxied GLP1R agonist was found to significantly associated with a decreased risk of diabetic nephropathy (OR = 0.72, 95%CI = 0.54–0.97, <i>p</i> = 0.031) and IgA nephropathy (OR = 0.58, 95%CI = 0.36–0.94, <i>p</i> = 0.027). …”

Table 4_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …”

Table 2_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 1, several lymphocyte subsets were significantly altered in the AKI group, including increased CD4⁺CD38⁺T%, CD8⁺CD38⁺T%, CD155⁺T%, CD4⁺TeM⁺T%, CD8⁺TIGIT⁺T%, and M-MDSC, and decreased CD4⁺LAG3⁺T%, CD4⁺TN⁺T%, and Th17 cells. …”