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14641
Table 1_Therapeutic potential of Triptolide in inhibiting breast cancer-induced bone destruction – PTHrP as a therapeutic target.docx
Published 2025“…</p>Results<p>TP treatment significantly reduced osteoclastogenesis in both co‐culture and conditioned medium systems. …”
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14642
Muscles influence motoneuron at NMJ during the critical period, but motoneuron do not affect GluR composition in muscles.
Published 2025“…<p><b>(A)</b> Heat stress experienced during the embryonic critical period (32°C vs. 25°C control) leads to decreased postsynaptic GluRIIA. Simultaneous genetic manipulation of aCC motoneuron during embryonic stages does not affect GluRIIA in muscles. …”
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14643
DataSheet1_The impact of statin use on short-term and long-term mortality in patients with heart failure.docx
Published 2024“…Low-dose statins can significantly reduce short-term and long-term mortality, while high-dose statins are not significantly correlated with mortality. …”
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14644
Image 2_Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.tif
Published 2025“…After AFs treatment at 0.1 g/kg, serum IgE levels were normalized to those of control animals. All AFs significantly decreased dermal mast cell and eosinophil counts, as well as epidermal thickening, with greater efficacy observed at lower doses. …”
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14645
Data Sheet 1_Prepandemic levels of cytokines and immunoglobulins and risk of SARS-CoV-2 infection and COVID-19 in the general population of Barcelona.docx
Published 2025“…</p>Results<p>Higher concentrations in 2016–17 of IL-8 and TNF-α significantly decreased the risk of SARS-CoV-2 seropositivity in 2020–21, whereas higher concentrations of MIP-1α were a risk factor for seropositivity. …”
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14646
Data Sheet 1_Suppressed intestinal secondary bile acids in moxifloxacin-induced hyperglycemia: studies in normal and diabetic GK rats.docx
Published 2025“…Gut microbiota associated with SBAs metabolism were significantly reduced, leading to decreased intestinal deoxycholic acid (DCA) and lithocholic acid (LCA). …”
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14647
Table 1_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx
Published 2025“…The miRNA cargo exhibited a similar pattern, except miR-141-3p, miR-153-3p, both increased slightly, and miR-223-3p, which increased substantially; miR-148a-3p, which decreased; and miR-33a-3p, which was no longer detectable after digestion. …”
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14648
Table 2_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx
Published 2025“…The miRNA cargo exhibited a similar pattern, except miR-141-3p, miR-153-3p, both increased slightly, and miR-223-3p, which increased substantially; miR-148a-3p, which decreased; and miR-33a-3p, which was no longer detectable after digestion. …”
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14649
Data Sheet 1_Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes.zip
Published 2025“…The mRNA expression of CERS3, which synthesizes ceramides containing long chain FAs, was increased by Th1/Th17 cytokines. Both Th1/ Th17 and Th2 cytokine mixtures lowered the CERS6 mRNA levels in differentiated keratinocytes. …”
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14650
Betulinic acid protects SH-SY5Y cells exposed to lipopolysaccharide and ferrous sulfate through p38MAPK/NF-κB/GPX4/Nrf2/keap-1/HO-1 signaling axis
Published 2025“…Furthermore, LPS and FeSO<sub>4</sub> significantly increased the expression of IL-6, TNF-α, and phosphorylation of p38, pMAPK, and pNFkB in the cells. …”
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14651
Data Sheet 2_Prognostic value of lymph node ratio in patients with non-small cell lung cancer: a systematic review and meta-analysis.zip
Published 2025“…</p>Results<p>This meta-analysis included 11 studies. High LNR was significantly associated with decreased overall survival (OS) (multivariable HR=1.76, 95% CI=1.36-2.27; univariable HR=2.26, 95% CI=1.95-2.63) and increased risk of shorter disease-free survival (DFS) (multivariable HR=1.66, 95% CI=1.48-1.88). …”
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14652
Supplementary file 1_Role and mechanism of IGFBP5 in the real-ambient particulate matter exposure-induced chronic lung injury.docx
Published 2025“…</p>Results<p>IGFBP5 was significantly downregulated after PM exposure. Functional investigations demonstrated that IGFBP5 downregulation exacerbated PM-induced oxidative damage, as evidenced by elevated levels of reactive oxygen species (ROS) and malondialdehyde, as well as decreased levels of superoxide dismutase 2 (SOD2). …”
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14653
Table 1_Effects of photoperiod on phytochemical profiles of four Ocimum basilicum genotypes in a hydroponic climate chamber.docx
Published 2025“…As demand for year-round high-quality basil increases, alternative approaches that ensure consistent phytochemical profiles are needed. …”
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14654
Data Sheet 1_MgSO4 alleviates hippocampal neuroinflammation and BBB damage to resist CMS-induced depression.docx
Published 2025“…These animals induced by CMS exhibited hippocampal neuroinflammation characterized by an elevated number of Iba<sup>+</sup> microglia with enlarged cell bodies and increased branching structures. In CMS-induced mice, MgSO<sub>4</sub> alleviated CMS-induced depressive-like behaviors and hypomagnesemia, reduced the levels of inflammatory cytokines in both serum and hippocampus, decreased the number of Iba<sup>+</sup> microglia, modulated microglia polarization and repaired the BBB damage. …”
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14655
Table 2_Effects of photoperiod on phytochemical profiles of four Ocimum basilicum genotypes in a hydroponic climate chamber.docx
Published 2025“…As demand for year-round high-quality basil increases, alternative approaches that ensure consistent phytochemical profiles are needed. …”
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14656
Table 1_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc
Published 2025“…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. …”
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14657
Data Sheet 1_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.pdf
Published 2025“…Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. Adipocytes secreted large amounts of IGFBP5. …”
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14658
Table 4_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc
Published 2025“…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. …”
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14659
Supplementary file 1_tRF-1:28-Val-CAC-2 promotes the development of nasopharyngeal cancer by targeting EPHB2.doc
Published 2025“…</p>Results<p>NPC cells exhibited tRF-1:28-Val-CAC-2 upregulation that was associated with significantly increased proliferative, migratory, and invasive activity together with the suppression of apoptotic death. …”
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14660
Data Sheet 1_Changes in the prevalence of hepatitis B virus and its related factors in Inner Mongolia between 2006 and 2020.doc
Published 2025“…By 2020, these proportions increased to 97.43 and 96.97%, respectively.</p>Conclusion<p>The prevalence of HBsAg decreased significantly from 2006 to 2020 in Inner Mongolia, suggesting that the Hep B vaccine has made remarkable progress in safeguarding the population against hepatitis B infection.…”