Data Sheet 9_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”

Data Sheet 6_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”

Data Sheet 8_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”

Supplementary file 1_Responses of fish population structure to barrage re-opening in an estuarine ecosystem.docx by Jeong-Soo Gim (18058588)

“…The Nakdong River Estuary (NRE), South Korea, provides a unique opportunity to assess the effects of temporary barrage re-opening on fish population structure.…”

Image 1_Mediation effects of metabolites and sex hormones on the relationship between body mass index and breast cancer: Mendelian randomization analysis and mediation analysis.jpg by Yanjiang Yang (13860452)

“…</p>Conclusion<p>This study discovered that BMI increases ER⁺BC risk through the pathway of sex hormones (biologically available testosterone), and decreases BC risk through multiple metabolite pathways causally. …”

Table 1_Mediation effects of metabolites and sex hormones on the relationship between body mass index and breast cancer: Mendelian randomization analysis and mediation analysis.xls by Yanjiang Yang (13860452)

“…</p>Conclusion<p>This study discovered that BMI increases ER⁺BC risk through the pathway of sex hormones (biologically available testosterone), and decreases BC risk through multiple metabolite pathways causally. …”

Table 2_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…Additionally, Muscone significantly inhibited the protein expression of CXCR3, IFN-γ, IL-17A, and RORγt in lung tissues of COPD mice.…”

Table 4_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…Additionally, Muscone significantly inhibited the protein expression of CXCR3, IFN-γ, IL-17A, and RORγt in lung tissues of COPD mice.…”

Table 5_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…Additionally, Muscone significantly inhibited the protein expression of CXCR3, IFN-γ, IL-17A, and RORγt in lung tissues of COPD mice.…”

Table 1_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…Additionally, Muscone significantly inhibited the protein expression of CXCR3, IFN-γ, IL-17A, and RORγt in lung tissues of COPD mice.…”

Table 3_The protective role of muscone in the development of COPD.xlsx by Tiantian Feng (2851097)

“…Additionally, Muscone significantly inhibited the protein expression of CXCR3, IFN-γ, IL-17A, and RORγt in lung tissues of COPD mice.…”

DataSheet1_Coptisine enhances the sensitivity of chemoresistant breast cancer cells by inhibiting the function and expression of ABC transporters.PDF by Safaa Yehia Eid (17768736)

“…In MCF-7/ADR and MDA-MB-231/ADR cells, COP (31 μM) enhanced DOX cytotoxicity with CI (0.77 and 0.75), RR (2.58 and 3.33), and IB suggesting synergism. COP significantly inhibits ABCT function in resistant BC cell lines, increases Rho123 accumulation, and decreases efflux more than VER; 2.1 and 1.2-fold, respectively. …”

Orsay virus infection does not modulate autophagic flux at 48hpi. by Gowri Kalugotla (10292196)

“…<p><b>(A)</b> Schematic showing how the autophagic flux reporter (AFR) is processed. …”

Data Sheet 1_Characteristics of cardiopulmonary exercise capacity in adults with different degrees of obesity.pdf by Shukun Deng (20583833)

“…</p>Conclusion<p>With the aggravation of obesity, the maximum exercise ability of adults decreases, VO_2peak/kg and VO₂/HR_max%Pred decreases, and the breathing reserve decreases.…”

Hesperetin attenuates ischemia/reperfusion-induced acute kidney injury by regulating ferroptosis in mice by Xiaoyu Xie (2568607)

“…Ferroptosis markers showed that hesperetin decreased levels of ACSL4 while increasing GPX4, FTH1, and SLC7A11, suggesting an anti-ferroptotic effect. …”

Data Sheet 1_Genome-wide development of SSR molecular markers for modern sugarcane cultivars.docx by Yi Xu (131145)

“…In this study, We searched for and identified SSR loci within the genomes of 14 Poaceae plants. Notably, a significant positive correlation (r = 0.958) was detected between genome size and the number of SSRs. …”

Aquaporin and red cell O2 permeability by S. Al-Samir (20965502)

“…In addition, the AQP1 inhibitor 5-(phenoxymethyl)furan-2-carbaldehyde) (5-PMFC) decreases human red cell PO2 by ~40%. All these effects are highly visible at 7/10°C, but minor or absent at 25°C and 37°C, suggesting that O2 passage through the channel(s) increases less with temperature than O2 permeation through membrane lipids. …”

Table 2_Isoenergetic reduction of dietary macronutrients affects body composition, physical activity, and post-prandial hormone responses in lean and obese cats fed to maintain bod... by Hannah Godfrey (12256593)

“…Post-prandial serum ghrelin decreased in all cats whereas serum peptide YY (PYY) increased at 1-, 2-, and 3-h post-prandial (P_Time = 0.0094 and P_Time = 0.0050). …”

Table 1_Isoenergetic reduction of dietary macronutrients affects body composition, physical activity, and post-prandial hormone responses in lean and obese cats fed to maintain bod... by Hannah Godfrey (12256593)

“…Post-prandial serum ghrelin decreased in all cats whereas serum peptide YY (PYY) increased at 1-, 2-, and 3-h post-prandial (P_Time = 0.0094 and P_Time = 0.0050). …”

HK2 regulates mRNA translation in melanoma cells. by Ana Luisa Dian (22258504)

“…HK2 depletion significantly decreased the abundance of <i>SOX10</i>, <i>CDH2</i>, and <i>WNT5A</i> mRNAs extracted from polysome fractions, but not in total RNAs. …”