Supplementary file 1_Global burden of childhood otitis media attributable to secondhand smoke from 1990 to 2021: a systematic analysis of the global burden of disease study 2021.pd... by Bei Li (90587)

“…Background<p>Childhood otitis media is significantly influenced by exposure to secondhand smoke (SHS), posing a considerable challenge to pediatric health. …”

Tanshinone I as a novel therapeutic agent targeting von Willebrand factor-binding protein to mitigate <i>Staphylococcus aureus</i> pathogenicity by Shiyu Zhou (457967)

“…This study underscores the potential of tanshinone I as a therapeutic agent against <i>S. aureus</i> infections, offering a novel strategy to combat bacterial infections while decreasing the critical issue of antibiotic resistance.…”

Table 1_S-equol status modulates skin response to soy isoflavones in postmenopausal women: results from a randomized placebo-controlled pilot trial.docx by Vineetha Vijayakumar (17064126)

“…</p>Results<p>Crow’s feet wrinkle roughness decreased by 5.6% in the Novasoy®400 group versus a 1.6% increase in the placebo group, this difference was not statistically significant. …”

Data Sheet 2_Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus.docx by Haoyi Yang (8215116)

“…Compared with those in the placebo group, the levels of several bile acids were significantly greater in the SY-009-treated groups. Moreover, the proportion of free bile acids decreased significantly, the proportion of glycine-conjugated bile acids increased significantly, the proportion of taurine-conjugated bile acids tended to be stable, and PBA/SBA significantly increased after SY-009 administration.…”

Data Sheet 1_Effect of SY009, a novel SGLT1 inhibitor, on the plasma metabolome and bile acids in patients with type 2 diabetes mellitus.docx by Haoyi Yang (8215116)

“…Compared with those in the placebo group, the levels of several bile acids were significantly greater in the SY-009-treated groups. Moreover, the proportion of free bile acids decreased significantly, the proportion of glycine-conjugated bile acids increased significantly, the proportion of taurine-conjugated bile acids tended to be stable, and PBA/SBA significantly increased after SY-009 administration.…”

Data Sheet 1_Correlation analysis of osteoporosis and vertebral endplate defects using CT and MRI imaging: a retrospective cross-sectional study.pdf by Song Hao (5700608)

“…</p>Conclusion<p>There was a correlation between OP and the size of the vertebral endplate defect, and the defect size increased with decreasing bone mass. …”

DataSheet1_Hypoglycemic activity of Garcinia mangostana L. extracts on diabetes rodent models: A systematic review and network meta-analysis.docx by Moragot Chatatikun (14682400)

“…Background<p>Diabetes mellitus is a significant global health issue, and alternative treatments from natural products like Garcinia mangostana L. …”

The efficacy and safety of Fluticasone Furoate/Umeclidinium/vilanterol (FF/UMEC/VI) on cough symptoms in adult patients with asthma, a randomized double-blind, placebo-controlled,... by Etsuko Tagaya (17601425)

“…The ACQ-5 scores showed a greater decrease in the FF/UMEC/VI group than in the placebo group. …”

Table 1_Impact of co-infections and immune responses on clinical severity of human adenovirus 3 and 7 infections in hospitalized children with lower respiratory tract infections: a... by Xiaolin Ma (701778)

“…</p>Conclusions<p>Hospitalized children with HAdV-7-associated LRTIs exhibit greater severity, multiple infections, and significant potential for greater cellular immune dysregulation compared to those with HAdV-3 infection, indicating a more severe clinical course and distinct pathogenic profiles.…”

Table 1_Sex-specific association between triglyceride-glucose index and all-cause mortality in patients with osteoporotic fractures: a retrospective cohort study.docx by Shao-han Guo (19690687)

“…Among female patients, each unit increase in the TyG-I was linked to a 37% greater risk of mortality. …”

Data Sheet 1_Biomarker-based risk assessment of dietary intervention in patients with coronary artery disease during cardiac rehabilitation—a quasi-experimental study.pdf by Mona Kotewitsch (12479136)

“…However, the low-fat and low-carb diet resulted in significantly greater reductions in BMI, body fat and visceral fat, with a tendency towards more stable effects over 6 months in the low-fat group. …”

Table_1_Effects of high-intensity interval training in a cold environment on arterial stiffness and cerebral hemodynamics in sedentary Chinese college female students post-COVID-19... by Xiangyuan Chen (9658136)

“…After training, the AS in the CE group significantly decreased (p < 0.05), with an average reduction of 11% in brachial-ankle pulse wave velocity, showing a significantly greater improvement compared to the RE group and the control group (p < 0.05), while no significant changes were observed in the RE group (p > 0.05). …”

Table_1_Effects of high-intensity interval training in a cold environment on arterial stiffness and cerebral hemodynamics in sedentary Chinese college female students post-COVID-19... by Xiangyuan Chen (9658136)

“…After training, the AS in the CE group significantly decreased (p < 0.05), with an average reduction of 11% in brachial-ankle pulse wave velocity, showing a significantly greater improvement compared to the RE group and the control group (p < 0.05), while no significant changes were observed in the RE group (p > 0.05). …”

Table 1_MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study.docx by Shengbo Yang (295144)

“…Inflammatory markers (CRP, LPS) decreased with higher adherence (all p < 0.001). Each 1-unit increase in MIND diet score was significantly associated with reductions in fasting insulin (β = −0.20 μU/mL; p < 0.001), HOMA-IR (β = −2.11; p < 0.001), CRP (β = −2.12; p < 0.001), LPS (β = −8.52; p < 0.001). …”

Table 2_MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study.docx by Shengbo Yang (295144)

“…Inflammatory markers (CRP, LPS) decreased with higher adherence (all p < 0.001). Each 1-unit increase in MIND diet score was significantly associated with reductions in fasting insulin (β = −0.20 μU/mL; p < 0.001), HOMA-IR (β = −2.11; p < 0.001), CRP (β = −2.12; p < 0.001), LPS (β = −8.52; p < 0.001). …”

Supplementary file 1_Sex-specific association between triglyceride-glucose index and all-cause mortality in patients with osteoporotic fractures: a retrospective cohort study.xlsx by Shao-han Guo (19690687)

“…Among female patients, each unit increase in the TyG-I was linked to a 37% greater risk of mortality. …”

Image 1_Double-lumen tubes verus single-lumen tube in patients undergoing minimally invasive cardiac surgery: a randomised, controlled clinical trial.pdf by Zhenzhong Wang (407028)

“…</p>Conclusions<p>Two-lung ventilation with single-lumen tube is easy to perform, significantly increases oxygenation, and decreases the incidence of postoperative complications and airway injuries. …”

Image 1_Snowmelt seepage fluxes of dissolved organic matter in forest and grassland – a molecular-level case study from the Hainich Critical Zone Exploratory, Germany.pdf by Chen Huang (202847)

“…This study, conducted at the Hainich Critical Zone Exploratory in Germany, seeks to address a significant gap in understanding the molecular impacts of snowmelt-induced DOM flows and their ability to alter soil ecosystems rapidly. …”

Data Sheet 1_Global, regional, and national trends in ischaemic stroke burden and risk factors among adults aged 20 + years (1990–2021): a systematic analysis of data from the Glob... by Sibo Liu (9975065)

“…Conversely, in subregions of southern sub-Saharan Africa, an increase was observed. Males consistently faced a greater burden of IS across all subgroups. …”

<b>The role of the </b><b>LncRNA </b><b>XIST/miR-15a-5p/ MN1</b><b>signaling </b><b>axis in gender disparities in bladder cancer prognosis</b> by Qingshui Wang (17151220)

“…Conversely, miR-15a-5p expression was downregulated in BC tissues, with a greater fold decrease observed in females.…”