DataSheet2_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.docx by Jung Hoon Cha (19723588)

“…Although the population of F4/80⁺CD11b⁺ intrahepatic mononuclear phagocytes remained unchanged, their infiltration and activation (CHIT1⁺MerTK⁺) significantly decreased in OATD-01-treated mice, compared with that observed in vehicle-treated mice.…”

DataSheet1_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.zip by Jung Hoon Cha (19723588)

“…Although the population of F4/80⁺CD11b⁺ intrahepatic mononuclear phagocytes remained unchanged, their infiltration and activation (CHIT1⁺MerTK⁺) significantly decreased in OATD-01-treated mice, compared with that observed in vehicle-treated mice.…”

Supplementary file 1_L-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in Ch... by Yanqin Li (499034)

“…Below this threshold, each 10-unit increase in TyG-BMI was associated with a 6% decrease in self-rated mental health risk (adjusted hazard ratio [aHR] = 0.94, 95% confidence interval [CI]: 0.90–0.99). …”

Image 1_L-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China.tiff by Yanqin Li (499034)

“…Below this threshold, each 10-unit increase in TyG-BMI was associated with a 6% decrease in self-rated mental health risk (adjusted hazard ratio [aHR] = 0.94, 95% confidence interval [CI]: 0.90–0.99). …”

DataSheet1_Causal effects of serum calcium, phosphate, and 25-hydroxyvitamin D on kidney function: a genetic correlation, pleiotropic analysis, and Mendelian randomization study.zi... by Yanjun Liang (4394089)

“…Similarly, serum P was associated with a decrease in eGFRcrea (beta −0.01, P-value 2.0E−04; beta −0.005, P-value 2.0E−03) and an increase in BUN (beta 0.02, P-value 3.0E−03; beta 0.02, P-value 7.5E−07). …”

Image 2_L-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China.tiff by Yanqin Li (499034)

“…Below this threshold, each 10-unit increase in TyG-BMI was associated with a 6% decrease in self-rated mental health risk (adjusted hazard ratio [aHR] = 0.94, 95% confidence interval [CI]: 0.90–0.99). …”

Altered spatial distribution of EPDCs in <i>Wt1</i>^Cre; <i>Sox9</i>^fl/fl; <i>R26</i>^mG hearts. by Andrew B. Harvey (21587431)

“…Chi-square analysis indicates a significant shift in spatial distribution (p < 0.0001). …”

MLN IFN- by Jessica Belmares-Ortega (21212731)

“…<p><b>γ</b><b>production is decreased in the absence of MyD88 and</b><b>αβ</b><b>T cells.…”

Preeclamptic plasma disrupts endothelial function and promotes inflammation in endothelial cells: beneficial effects of glibenclamide and MCC950 in this scenario by Karoliny Nune Santos (21752603)

“…Both GB and MCC950 reduced NLRP3 inflammasome activation and its related effects in ECs exposed to PE plasma, including lowered IL-1β, caspase-1, modulated adhesion molecules expression, as well as decreased ROS and cytotoxicity. GB increased NO and restored VE-cadherin expression, while MCC950 enhanced antioxidant capacity. …”

Algorithms for designing continuous curricula A: Decision tree showing the continuous version of ADP which includes actions that “grow” and “shrink” the increments between continuo... by William L. Tong (22238845)

“…Continuous ADP first decreases increment size and smoothly increases the difficulty level while balancing reinforcement and extinction.…”

TITAN analyses. by Erik W. Ertsgaard (20521628)

“…<p>Taxa significantly associated with increasing or decreasing MAP in our TITAN. …”

Data Sheet 1_Disease spectrum of patients with hospital-acquired multidrug-resistant organism infections in the intensive care unit: a retrospective study.doc by Xiaowu Wang (167537)

“…</p>Conclusion<p>Our data show the mortality rate of hospital-acquired MDRO infections decreased during COVID-19 and increased after restrictions eased. …”

Data Sheet 1_Impact of self-reported SARS-CoV-2 antibody positivity on cardiac structure and function: findings from UK Biobank CMR cohort.docx by Chang Liu (35901)

“…Over an average follow-up period of 110 days, significant decreases in CO and CI were observed in the paired participants. …”

Table 1_Dietary quercetagetin attenuates H2O2-induced oxidative damage and preserves meat quality in broilers by modulating redox status and Nrf2/ferroptosis signaling pathway.docx by Wenyue Hu (799025)

“…Meanwhile, the addition of QG to the diet increased the mRNA expressions of Nrf2 and TFR1, showing no significant difference from those of the control group. …”

Supplementary file 1_Association between changes in corrected anion gap and mortality among critically ill patients during ICU stay: a multicenter observational study.doc by Yanli Hou (6561536)

“…When analyzed categorically, the ΔcAG still exhibited a significant risk gradient across quartiles.</p>Conclusion<p>Further elevated cAG after ICU admission demonstrates a robust association with an increased mortality risk in critically ill patients. …”

FLEXI interactions with RNA-binding proteins. by Jun Yao (9646)

“…RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …”

Table 1_Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy cohort.docx by Yanyan Mao (1998469)

“…The modification displayed a quasi-U-shaped distribution in relation to BPA and decreased as TSH levels increased.</p>…”

Supplementary file 1_Global, regional, and national total burden related to hepatitis B and attributable risk factors in adults aged 65 years and older from 1990 to 2021 and projec... by Linying Gao (4379200)

“…The ASIR increased only in the >95 years age group, while a significant increase in DALYs was observed across all age strata, with the magnitude of increase escalating with advancing age. …”

Presentation 1_Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy coho... by Yanyan Mao (1998469)

“…The modification displayed a quasi-U-shaped distribution in relation to BPA and decreased as TSH levels increased.</p>…”

Image 1_Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy cohort.pdf by Yanyan Mao (1998469)

“…The modification displayed a quasi-U-shaped distribution in relation to BPA and decreased as TSH levels increased.</p>…”